Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| endothelial cell of lymphatic vessel | 21 studies | 44% ± 17% | |
| GABAergic neuron | 6 studies | 31% ± 15% | |
| interneuron | 5 studies | 30% ± 18% | |
| endothelial cell | 4 studies | 59% ± 26% | |
| endothelial cell of sinusoid | 3 studies | 34% ± 15% | |
| glutamatergic neuron | 3 studies | 44% ± 27% | |
| GABAergic interneuron | 3 studies | 24% ± 3% | |
| granule cell | 3 studies | 84% ± 7% | |
| neuron | 3 studies | 41% ± 31% | |
| ON-bipolar cell | 3 studies | 28% ± 9% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| brain | 4 studies | 32% ± 8% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| liver | 98% | 1812.18 | 221 / 226 | 65% | 17.12 | 263 / 406 |
| brain | 93% | 7985.59 | 2460 / 2642 | 64% | 4.44 | 450 / 705 |
| prostate | 57% | 377.12 | 140 / 245 | 83% | 5.84 | 417 / 502 |
| thymus | 96% | 1303.02 | 628 / 653 | 10% | 0.22 | 62 / 605 |
| adrenal gland | 48% | 442.89 | 124 / 258 | 56% | 18.96 | 128 / 230 |
| breast | 74% | 790.54 | 341 / 459 | 21% | 0.96 | 237 / 1118 |
| esophagus | 68% | 592.65 | 983 / 1445 | 13% | 0.44 | 24 / 183 |
| lung | 60% | 330.02 | 346 / 578 | 20% | 1.07 | 228 / 1155 |
| intestine | 66% | 479.46 | 636 / 966 | 10% | 0.30 | 55 / 527 |
| skin | 54% | 440.96 | 981 / 1809 | 22% | 6.13 | 102 / 472 |
| bladder | 67% | 392.48 | 14 / 21 | 9% | 0.84 | 46 / 504 |
| adipose | 70% | 603.43 | 848 / 1204 | 0% | 0 | 0 / 0 |
| kidney | 20% | 84.08 | 18 / 89 | 39% | 6.58 | 352 / 901 |
| ovary | 28% | 165.28 | 51 / 180 | 26% | 1.61 | 110 / 430 |
| stomach | 35% | 239.14 | 124 / 359 | 17% | 1.34 | 49 / 286 |
| uterus | 38% | 193.34 | 64 / 170 | 14% | 0.83 | 63 / 459 |
| pancreas | 3% | 13.74 | 9 / 328 | 48% | 3.98 | 86 / 178 |
| heart | 50% | 458.60 | 427 / 861 | 0% | 0 | 0 / 0 |
| blood vessel | 29% | 283.76 | 392 / 1335 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 9% | 0.32 | 7 / 80 |
| spleen | 7% | 29.22 | 18 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 7% | 0.25 | 3 / 45 |
| muscle | 6% | 30.84 | 51 / 803 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 3% | 0.04 | 1 / 29 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| peripheral blood | 0% | 0 | 0 / 929 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0045664 | Biological process | regulation of neuron differentiation |
| GO_0097477 | Biological process | lateral motor column neuron migration |
| GO_0097119 | Biological process | postsynaptic density protein 95 clustering |
| GO_0010468 | Biological process | regulation of gene expression |
| GO_0021766 | Biological process | hippocampus development |
| GO_0021511 | Biological process | spinal cord patterning |
| GO_0050804 | Biological process | modulation of chemical synaptic transmission |
| GO_0010976 | Biological process | positive regulation of neuron projection development |
| GO_0061003 | Biological process | positive regulation of dendritic spine morphogenesis |
| GO_2001222 | Biological process | regulation of neuron migration |
| GO_0007616 | Biological process | long-term memory |
| GO_0021517 | Biological process | ventral spinal cord development |
| GO_0060025 | Biological process | regulation of synaptic activity |
| GO_0010001 | Biological process | glial cell differentiation |
| GO_0097120 | Biological process | receptor localization to synapse |
| GO_2000310 | Biological process | regulation of NMDA receptor activity |
| GO_0008306 | Biological process | associative learning |
| GO_0050795 | Biological process | regulation of behavior |
| GO_0021819 | Biological process | layer formation in cerebral cortex |
| GO_0001764 | Biological process | neuron migration |
| GO_1902078 | Biological process | positive regulation of lateral motor column neuron migration |
| GO_0007155 | Biological process | cell adhesion |
| GO_0001934 | Biological process | positive regulation of protein phosphorylation |
| GO_0060291 | Biological process | long-term synaptic potentiation |
| GO_0097114 | Biological process | NMDA glutamate receptor clustering |
| GO_2000463 | Biological process | positive regulation of excitatory postsynaptic potential |
| GO_0045860 | Biological process | positive regulation of protein kinase activity |
| GO_0018108 | Biological process | peptidyl-tyrosine phosphorylation |
| GO_0048265 | Biological process | response to pain |
| GO_0050731 | Biological process | positive regulation of peptidyl-tyrosine phosphorylation |
| GO_0038026 | Biological process | reelin-mediated signaling pathway |
| GO_0021800 | Biological process | cerebral cortex tangential migration |
| GO_1904936 | Biological process | interneuron migration |
| GO_0006508 | Biological process | proteolysis |
| GO_1900273 | Biological process | positive regulation of long-term synaptic potentiation |
| GO_0051057 | Biological process | positive regulation of small GTPase mediated signal transduction |
| GO_0007417 | Biological process | central nervous system development |
| GO_0007420 | Biological process | brain development |
| GO_0090129 | Biological process | positive regulation of synapse maturation |
| GO_0051897 | Biological process | positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction |
| GO_0051968 | Biological process | positive regulation of synaptic transmission, glutamatergic |
| GO_0000902 | Biological process | cell morphogenesis |
| GO_0035418 | Biological process | protein localization to synapse |
| GO_0016358 | Biological process | dendrite development |
| GO_0032008 | Biological process | positive regulation of TOR signaling |
| GO_0007626 | Biological process | locomotory behavior |
| GO_0007411 | Biological process | axon guidance |
| GO_0097107 | Biological process | postsynaptic density assembly |
| GO_0005615 | Cellular component | extracellular space |
| GO_0110157 | Cellular component | reelin complex |
| GO_0005576 | Cellular component | extracellular region |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0031012 | Cellular component | extracellular matrix |
| GO_0043005 | Cellular component | neuron projection |
| GO_0030425 | Cellular component | dendrite |
| GO_0005737 | Cellular component | cytoplasm |
| GO_0048018 | Molecular function | receptor ligand activity |
| GO_0008236 | Molecular function | serine-type peptidase activity |
| GO_0046872 | Molecular function | metal ion binding |
| GO_0070326 | Molecular function | very-low-density lipoprotein particle receptor binding |
| GO_0070325 | Molecular function | lipoprotein particle receptor binding |
| Gene name | RELN |
| Protein name | Uncharacterized protein RELN Reelin (EC 3.4.21.-) Reelin Alternative protein RELN |
| Synonyms | |
| Description | FUNCTION: Extracellular matrix serine protease that plays a role in layering of neurons in the cerebral cortex and cerebellum. Regulates microtubule function in neurons and neuronal migration. Affects migration of sympathetic preganglionic neurons in the spinal cord, where it seems to act as a barrier to neuronal migration. Enzymatic activity is important for the modulation of cell adhesion. Binding to the extracellular domains of lipoprotein receptors VLDLR and LRP8/APOER2 induces tyrosine phosphorylation of DAB1 and modulation of TAU phosphorylation (By similarity). . FUNCTION: Extracellular matrix serine protease that plays a role in layering of neurons in the cerebral cortex and cerebellum. Regulates microtubule function in neurons and neuronal migration. Affects migration of sympathetic preganglionic neurons in the spinal cord, where it seems to act as a barrier to neuronal migration. Enzymatic activity is important for the modulation of cell adhesion. Binding to the extracellular domains of lipoprotein receptors VLDLR and LRP8/APOER2 induces tyrosine phosphorylation of DAB1 and modulation of TAU phosphorylation. . FUNCTION: Extracellular matrix serine protease that plays a role in layering of neurons in the cerebral cortex and cerebellum. Regulates microtubule function in neurons and neuronal migration. Affects migration of sympathetic preganglionic neurons in the spinal cord, where it seems to act as a barrier to neuronal migration. Enzymatic activity is important for the modulation of cell adhesion. Binding to the extracellular domains of lipoprotein receptors VLDLR and LRP8/APOER2 induces tyrosine phosphorylation of DAB1 and modulation of TAU phosphorylation. . FUNCTION: Extracellular matrix serine protease that plays a role in layering of neurons in the cerebral cortex and cerebellum. Regulates microtubule function in neurons and neuronal migration. Affects migration of sympathetic preganglionic neurons in the spinal cord, where it seems to act as a barrier to neuronal migration. Enzymatic activity is important for the modulation of cell adhesion. Binding to the extracellular domains of lipoprotein receptors VLDLR and LRP8/APOER2 induces tyrosine phosphorylation of DAB1 and modulation of TAU phosphorylation. . |
| Accessions | H7C2B0 L8E7R1 Q75MM8 ENST00000424685.3 ENST00000428762.6 [P78509-1] A0A7P0TA83 ENST00000429186.2 ENST00000681034.1 ENST00000343529.9 [P78509-2] J3KQ66 P78509 |
