Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| fibroblast | 13 studies | 26% ± 6% | |
| basal cell | 7 studies | 26% ± 10% | |
| connective tissue cell | 6 studies | 26% ± 9% | |
| secretory cell | 3 studies | 23% ± 9% | |
| ciliated cell | 3 studies | 25% ± 7% |
Insufficient scRNA-seq data for expression of TPBG at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| breast | 100% | 2790.58 | 457 / 459 | 99% | 84.08 | 1103 / 1118 |
| esophagus | 100% | 8929.64 | 1445 / 1445 | 97% | 68.09 | 178 / 183 |
| uterus | 100% | 2431.82 | 170 / 170 | 96% | 62.81 | 439 / 459 |
| thymus | 100% | 2518.33 | 652 / 653 | 90% | 26.93 | 543 / 605 |
| lung | 95% | 1147.54 | 547 / 578 | 95% | 50.23 | 1093 / 1155 |
| bladder | 100% | 4978.43 | 21 / 21 | 88% | 39.47 | 446 / 504 |
| prostate | 100% | 2373.31 | 245 / 245 | 77% | 14.58 | 389 / 502 |
| intestine | 93% | 1075.33 | 900 / 966 | 77% | 20.87 | 405 / 527 |
| pancreas | 70% | 618.23 | 230 / 328 | 94% | 40.74 | 168 / 178 |
| kidney | 88% | 1315.18 | 78 / 89 | 73% | 16.97 | 662 / 901 |
| stomach | 88% | 1024.43 | 317 / 359 | 72% | 18.95 | 205 / 286 |
| ovary | 71% | 776.27 | 128 / 180 | 83% | 31.43 | 359 / 430 |
| skin | 100% | 6643.48 | 1807 / 1809 | 43% | 11.79 | 204 / 472 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 60.06 | 45 / 45 |
| ureter | 0% | 0 | 0 / 0 | 100% | 11.59 | 1 / 1 |
| adipose | 99% | 2351.38 | 1197 / 1204 | 0% | 0 | 0 / 0 |
| blood vessel | 98% | 1994.28 | 1313 / 1335 | 0% | 0 | 0 / 0 |
| spleen | 96% | 1463.45 | 232 / 241 | 0% | 0 | 0 / 0 |
| heart | 63% | 634.77 | 539 / 861 | 0% | 0 | 0 / 0 |
| brain | 45% | 858.12 | 1182 / 2642 | 16% | 4.16 | 112 / 705 |
| adrenal gland | 22% | 159.05 | 56 / 258 | 38% | 11.63 | 87 / 230 |
| eye | 0% | 0 | 0 / 0 | 23% | 2.54 | 18 / 80 |
| liver | 1% | 5.60 | 2 / 226 | 14% | 3.89 | 57 / 406 |
| lymph node | 0% | 0 | 0 / 0 | 10% | 1.26 | 3 / 29 |
| muscle | 9% | 58.45 | 71 / 803 | 0% | 0 | 0 / 0 |
| peripheral blood | 6% | 77.55 | 58 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0090497 | Biological process | mesenchymal cell migration |
| GO_0140059 | Biological process | dendrite arborization |
| GO_0051897 | Biological process | positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction |
| GO_0051932 | Biological process | synaptic transmission, GABAergic |
| GO_0008285 | Biological process | negative regulation of cell population proliferation |
| GO_0072659 | Biological process | protein localization to plasma membrane |
| GO_0007155 | Biological process | cell adhesion |
| GO_0051965 | Biological process | positive regulation of synapse assembly |
| GO_0070374 | Biological process | positive regulation of ERK1 and ERK2 cascade |
| GO_0008355 | Biological process | olfactory learning |
| GO_0060326 | Biological process | cell chemotaxis |
| GO_0090090 | Biological process | negative regulation of canonical Wnt signaling pathway |
| GO_0050921 | Biological process | positive regulation of chemotaxis |
| GO_0009986 | Cellular component | cell surface |
| GO_0043679 | Cellular component | axon terminus |
| GO_0005783 | Cellular component | endoplasmic reticulum |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0030425 | Cellular component | dendrite |
| Gene name | TPBG |
| Protein name | Trophoblast glycoprotein (5T4 oncofetal antigen) (5T4 oncofetal trophoblast glycoprotein) (5T4 oncotrophoblast glycoprotein) (M6P1) (Wnt-activated inhibitory factor 1) (WAIF1) |
| Synonyms | 5T4 |
| Description | FUNCTION: May function as an inhibitor of Wnt/beta-catenin signaling by indirectly interacting with LRP6 and blocking Wnt3a-dependent LRP6 internalization. . |
| Accessions | ENST00000634817.1 ENST00000543496.3 ENST00000369750.4 ENST00000535040.4 ENST00000634826.1 Q13641 ENST00000635036.3 |
