Name | Number of supported studies | Average coverage | |
---|---|---|---|
glutamatergic neuron | 5 studies | 41% ± 20% | |
neuron | 4 studies | 20% ± 4% | |
GABAergic neuron | 4 studies | 38% ± 13% | |
interneuron | 4 studies | 32% ± 18% | |
classical monocyte | 3 studies | 22% ± 1% | |
endothelial cell | 3 studies | 18% ± 4% | |
epithelial cell | 3 studies | 25% ± 2% | |
dendritic cell | 3 studies | 26% ± 7% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
esophagus | 100% | 834.67 | 1444 / 1445 | 100% | 23.90 | 183 / 183 |
brain | 100% | 2012.71 | 2636 / 2642 | 100% | 19.54 | 705 / 705 |
breast | 100% | 1181.61 | 459 / 459 | 100% | 34.07 | 1113 / 1118 |
ovary | 100% | 1158.65 | 180 / 180 | 100% | 18.82 | 428 / 430 |
uterus | 100% | 989.23 | 170 / 170 | 99% | 20.35 | 456 / 459 |
lung | 99% | 818.01 | 574 / 578 | 100% | 27.58 | 1154 / 1155 |
bladder | 100% | 829.19 | 21 / 21 | 99% | 18.54 | 498 / 504 |
thymus | 100% | 899.02 | 651 / 653 | 99% | 16.87 | 599 / 605 |
prostate | 100% | 979.65 | 245 / 245 | 99% | 15.31 | 495 / 502 |
intestine | 100% | 785.42 | 966 / 966 | 98% | 15.49 | 515 / 527 |
kidney | 100% | 825.90 | 89 / 89 | 97% | 14.54 | 874 / 901 |
stomach | 99% | 549.18 | 357 / 359 | 98% | 17.09 | 279 / 286 |
adrenal gland | 100% | 750.67 | 258 / 258 | 96% | 13.26 | 221 / 230 |
pancreas | 96% | 416.55 | 314 / 328 | 99% | 14.58 | 177 / 178 |
skin | 100% | 1233.99 | 1807 / 1809 | 93% | 19.32 | 440 / 472 |
liver | 100% | 1070.36 | 225 / 226 | 88% | 9.96 | 356 / 406 |
spleen | 100% | 756.95 | 241 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 23.23 | 45 / 45 |
ureter | 0% | 0 | 0 / 0 | 100% | 16.27 | 1 / 1 |
adipose | 100% | 1337.74 | 1203 / 1204 | 0% | 0 | 0 / 0 |
blood vessel | 100% | 927.70 | 1333 / 1335 | 0% | 0 | 0 / 0 |
muscle | 97% | 462.78 | 781 / 803 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 97% | 11.58 | 28 / 29 |
heart | 95% | 473.53 | 817 / 861 | 0% | 0 | 0 / 0 |
peripheral blood | 85% | 727.23 | 793 / 929 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 80% | 9.51 | 64 / 80 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0030838 | Biological process | positive regulation of actin filament polymerization |
GO_0072659 | Biological process | protein localization to plasma membrane |
GO_0051496 | Biological process | positive regulation of stress fiber assembly |
GO_0071364 | Biological process | cellular response to epidermal growth factor stimulus |
GO_0010763 | Biological process | positive regulation of fibroblast migration |
GO_0033138 | Biological process | positive regulation of peptidyl-serine phosphorylation |
GO_0097178 | Biological process | ruffle assembly |
GO_0045785 | Biological process | positive regulation of cell adhesion |
GO_0090367 | Biological process | negative regulation of mRNA modification |
GO_0006457 | Biological process | protein folding |
GO_0071356 | Biological process | cellular response to tumor necrosis factor |
GO_0043066 | Biological process | negative regulation of apoptotic process |
GO_0050821 | Biological process | protein stabilization |
GO_0051897 | Biological process | positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction |
GO_1903215 | Biological process | negative regulation of protein targeting to mitochondrion |
GO_0005886 | Cellular component | plasma membrane |
GO_0016020 | Cellular component | membrane |
GO_0005829 | Cellular component | cytosol |
GO_0005737 | Cellular component | cytoplasm |
GO_0005634 | Cellular component | nucleus |
GO_0000774 | Molecular function | adenyl-nucleotide exchange factor activity |
GO_0044877 | Molecular function | protein-containing complex binding |
GO_0031625 | Molecular function | ubiquitin protein ligase binding |
GO_0051087 | Molecular function | protein-folding chaperone binding |
GO_0003723 | Molecular function | RNA binding |
GO_0005515 | Molecular function | protein binding |
Gene name | BAG4 |
Protein name | BAG family molecular chaperone regulator 4 (BAG-4) (Bcl-2-associated athanogene 4) (Silencer of death domains) BAG cochaperone 4 |
Synonyms | SODD |
Description | FUNCTION: Inhibits the chaperone activity of HSP70/HSC70 by promoting substrate release (By similarity). Prevents constitutive TNFRSF1A signaling. Negative regulator of PRKN translocation to damaged mitochondria. . |
Accessions | ENST00000432471.6 [O95429-2] ENST00000521311.1 O95429 H0YBT1 ENST00000287322.5 [O95429-1] |