BAG4 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0030838Biological processpositive regulation of actin filament polymerization
GO_0072659Biological processprotein localization to plasma membrane
GO_0051496Biological processpositive regulation of stress fiber assembly
GO_0071364Biological processcellular response to epidermal growth factor stimulus
GO_0010763Biological processpositive regulation of fibroblast migration
GO_0033138Biological processpositive regulation of peptidyl-serine phosphorylation
GO_0097178Biological processruffle assembly
GO_0045785Biological processpositive regulation of cell adhesion
GO_0090367Biological processnegative regulation of mRNA modification
GO_0006457Biological processprotein folding
GO_0071356Biological processcellular response to tumor necrosis factor
GO_0043066Biological processnegative regulation of apoptotic process
GO_0050821Biological processprotein stabilization
GO_0051897Biological processpositive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
GO_1903215Biological processnegative regulation of protein targeting to mitochondrion
GO_0005886Cellular componentplasma membrane
GO_0016020Cellular componentmembrane
GO_0005829Cellular componentcytosol
GO_0005737Cellular componentcytoplasm
GO_0005634Cellular componentnucleus
GO_0000774Molecular functionadenyl-nucleotide exchange factor activity
GO_0044877Molecular functionprotein-containing complex binding
GO_0031625Molecular functionubiquitin protein ligase binding
GO_0051087Molecular functionprotein-folding chaperone binding
GO_0003723Molecular functionRNA binding
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameBAG4
Protein nameBAG family molecular chaperone regulator 4 (BAG-4) (Bcl-2-associated athanogene 4) (Silencer of death domains)
BAG cochaperone 4
SynonymsSODD
DescriptionFUNCTION: Inhibits the chaperone activity of HSP70/HSC70 by promoting substrate release (By similarity). Prevents constitutive TNFRSF1A signaling. Negative regulator of PRKN translocation to damaged mitochondria. .

AccessionsENST00000432471.6 [O95429-2]
ENST00000521311.1
O95429
H0YBT1
ENST00000287322.5 [O95429-1]