Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
lung | 100% | 871.57 | 576 / 578 | 90% | 4.38 | 1037 / 1155 |
intestine | 78% | 400.61 | 751 / 966 | 64% | 2.42 | 336 / 527 |
breast | 58% | 84.73 | 268 / 459 | 81% | 2.89 | 903 / 1118 |
kidney | 55% | 114.93 | 49 / 89 | 82% | 3.41 | 735 / 901 |
esophagus | 58% | 91.25 | 841 / 1445 | 73% | 2.25 | 133 / 183 |
stomach | 52% | 104.33 | 188 / 359 | 72% | 3.50 | 206 / 286 |
bladder | 62% | 147.52 | 13 / 21 | 55% | 2.95 | 277 / 504 |
thymus | 54% | 116.57 | 352 / 653 | 62% | 2.25 | 374 / 605 |
lymph node | 0% | 0 | 0 / 0 | 100% | 102.33 | 29 / 29 |
peripheral blood | 100% | 13989.60 | 929 / 929 | 0% | 0 | 0 / 0 |
spleen | 100% | 4511.85 | 241 / 241 | 0% | 0 | 0 / 0 |
prostate | 60% | 95.20 | 148 / 245 | 37% | 0.71 | 188 / 502 |
ovary | 18% | 22.23 | 33 / 180 | 79% | 2.99 | 341 / 430 |
uterus | 30% | 37.31 | 51 / 170 | 64% | 2.27 | 296 / 459 |
brain | 25% | 37.81 | 657 / 2642 | 69% | 2.70 | 484 / 705 |
liver | 58% | 87.65 | 130 / 226 | 34% | 1.12 | 139 / 406 |
tonsil | 0% | 0 | 0 / 0 | 91% | 5.86 | 41 / 45 |
pancreas | 11% | 15.33 | 37 / 328 | 79% | 3.69 | 140 / 178 |
adrenal gland | 60% | 87.64 | 156 / 258 | 24% | 0.44 | 55 / 230 |
adipose | 83% | 211.18 | 995 / 1204 | 0% | 0 | 0 / 0 |
skin | 5% | 4.90 | 92 / 1809 | 74% | 5.59 | 351 / 472 |
eye | 0% | 0 | 0 / 0 | 48% | 1.53 | 38 / 80 |
blood vessel | 47% | 103.44 | 631 / 1335 | 0% | 0 | 0 / 0 |
heart | 41% | 56.49 | 352 / 861 | 0% | 0 | 0 / 0 |
muscle | 2% | 2.61 | 19 / 803 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0071333 | Biological process | cellular response to glucose stimulus |
GO_0045730 | Biological process | respiratory burst |
GO_0034614 | Biological process | cellular response to reactive oxygen species |
GO_0045741 | Biological process | positive regulation of epidermal growth factor-activated receptor activity |
GO_0045087 | Biological process | innate immune response |
GO_0042554 | Biological process | superoxide anion generation |
GO_0046330 | Biological process | positive regulation of JNK cascade |
GO_0071276 | Biological process | cellular response to cadmium ion |
GO_0071394 | Biological process | cellular response to testosterone stimulus |
GO_0006968 | Biological process | cellular defense response |
GO_0006612 | Biological process | protein targeting to membrane |
GO_1900745 | Biological process | positive regulation of p38MAPK cascade |
GO_0060264 | Biological process | regulation of respiratory burst involved in inflammatory response |
GO_0045893 | Biological process | positive regulation of DNA-templated transcription |
GO_1903409 | Biological process | reactive oxygen species biosynthetic process |
GO_0051897 | Biological process | positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction |
GO_0006801 | Biological process | superoxide metabolic process |
GO_0005886 | Cellular component | plasma membrane |
GO_0016020 | Cellular component | membrane |
GO_0009898 | Cellular component | cytoplasmic side of plasma membrane |
GO_0043025 | Cellular component | neuronal cell body |
GO_0043020 | Cellular component | NADPH oxidase complex |
GO_0032010 | Cellular component | phagolysosome |
GO_0030425 | Cellular component | dendrite |
GO_0005829 | Cellular component | cytosol |
GO_0005737 | Cellular component | cytoplasm |
GO_0009055 | Molecular function | electron transfer activity |
GO_0035091 | Molecular function | phosphatidylinositol binding |
GO_0016176 | Molecular function | superoxide-generating NADPH oxidase activator activity |
GO_0016175 | Molecular function | superoxide-generating NAD(P)H oxidase activity |
GO_0005515 | Molecular function | protein binding |
GO_0043325 | Molecular function | phosphatidylinositol-3,4-bisphosphate binding |
GO_0017124 | Molecular function | SH3 domain binding |
Gene name | NCF1 |
Protein name | Neutrophil cytosolic factor 1 Neutrophil cytosol factor 1 (NCF-1) (47 kDa autosomal chronic granulomatous disease protein) (47 kDa neutrophil oxidase factor) (NCF-47K) (Neutrophil NADPH oxidase factor 1) (Nox organizer 2) (Nox-organizing protein 2) (SH3 and PX domain-containing protein 1A) (p47-phox) |
Synonyms | NOXO2 SH3PXD1A |
Description | FUNCTION: NCF2, NCF1, and a membrane bound cytochrome b558 are required for activation of the latent NADPH oxidase (necessary for superoxide production). . |
Accessions | ENST00000442021.6 ENST00000289473.11 [P14598-1] H7C1S1 ENST00000433458.5 P14598 C9J155 ENST00000464878.5 A0A087X1W0 |