Name | Number of supported studies | Average coverage | |
---|---|---|---|
fibroblast | 41 studies | 50% ± 26% | |
smooth muscle cell | 33 studies | 57% ± 19% | |
pericyte | 32 studies | 47% ± 22% | |
connective tissue cell | 19 studies | 54% ± 21% | |
ciliated cell | 18 studies | 44% ± 17% | |
endothelial cell | 18 studies | 37% ± 21% | |
myofibroblast cell | 13 studies | 59% ± 19% | |
endothelial cell of lymphatic vessel | 12 studies | 30% ± 8% | |
mesothelial cell | 9 studies | 64% ± 23% | |
basal cell | 8 studies | 26% ± 9% | |
renal alpha-intercalated cell | 7 studies | 55% ± 24% | |
abnormal cell | 7 studies | 26% ± 5% | |
ionocyte | 5 studies | 55% ± 20% | |
astrocyte | 5 studies | 27% ± 3% | |
renal beta-intercalated cell | 5 studies | 68% ± 25% | |
adipocyte | 5 studies | 43% ± 32% | |
Mueller cell | 5 studies | 59% ± 16% | |
glomerular endothelial cell | 4 studies | 100% ± 0% | |
progenitor cell | 4 studies | 37% ± 5% | |
neuroendocrine cell | 4 studies | 73% ± 30% | |
epithelial cell | 4 studies | 26% ± 8% | |
adventitial cell | 4 studies | 51% ± 10% | |
secretory cell | 3 studies | 31% ± 8% | |
oligodendrocyte precursor cell | 3 studies | 37% ± 18% | |
neural crest cell | 3 studies | 52% ± 12% | |
interneuron | 3 studies | 31% ± 5% | |
retinal pigment epithelial cell | 3 studies | 41% ± 15% | |
myoepithelial cell | 3 studies | 50% ± 25% | |
glial cell | 3 studies | 35% ± 21% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
breast | 99% | 107495.98 | 456 / 459 | 90% | 875.90 | 1002 / 1118 |
prostate | 99% | 76965.12 | 242 / 245 | 88% | 271.70 | 442 / 502 |
thymus | 100% | 106277.44 | 651 / 653 | 86% | 1117.97 | 522 / 605 |
kidney | 100% | 85111.37 | 89 / 89 | 72% | 498.35 | 645 / 901 |
ovary | 100% | 368564.23 | 180 / 180 | 65% | 206.18 | 278 / 430 |
stomach | 97% | 80997.79 | 348 / 359 | 65% | 207.10 | 186 / 286 |
intestine | 95% | 55780.92 | 921 / 966 | 58% | 170.92 | 306 / 527 |
adrenal gland | 100% | 62188.39 | 258 / 258 | 53% | 196.85 | 121 / 230 |
esophagus | 94% | 58551.54 | 1362 / 1445 | 58% | 153.33 | 106 / 183 |
bladder | 100% | 82625.14 | 21 / 21 | 48% | 139.38 | 243 / 504 |
lung | 70% | 21766.90 | 405 / 578 | 78% | 295.01 | 896 / 1155 |
uterus | 99% | 260996.27 | 169 / 170 | 44% | 324.56 | 200 / 459 |
skin | 58% | 24197.67 | 1049 / 1809 | 46% | 339.44 | 219 / 472 |
ureter | 0% | 0 | 0 / 0 | 100% | 125.57 | 1 / 1 |
adipose | 100% | 107641.31 | 1202 / 1204 | 0% | 0 | 0 / 0 |
blood vessel | 100% | 98441.37 | 1331 / 1335 | 0% | 0 | 0 / 0 |
pancreas | 5% | 1127.90 | 17 / 328 | 87% | 530.36 | 155 / 178 |
muscle | 91% | 45193.66 | 733 / 803 | 0% | 0 | 0 / 0 |
heart | 83% | 25668.83 | 713 / 861 | 0% | 0 | 0 / 0 |
brain | 5% | 827.31 | 126 / 2642 | 75% | 315.68 | 531 / 705 |
tonsil | 0% | 0 | 0 / 0 | 36% | 72.50 | 16 / 45 |
liver | 8% | 1386.40 | 17 / 226 | 14% | 31.07 | 57 / 406 |
spleen | 12% | 2499.57 | 28 / 241 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 6% | 10.72 | 5 / 80 |
lymph node | 0% | 0 | 0 / 0 | 3% | 4.30 | 1 / 29 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
peripheral blood | 0% | 0 | 0 / 929 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0014912 | Biological process | negative regulation of smooth muscle cell migration |
GO_0042593 | Biological process | glucose homeostasis |
GO_0001558 | Biological process | regulation of cell growth |
GO_0001649 | Biological process | osteoblast differentiation |
GO_0048009 | Biological process | insulin-like growth factor receptor signaling pathway |
GO_0007165 | Biological process | signal transduction |
GO_0031069 | Biological process | hair follicle morphogenesis |
GO_0051146 | Biological process | striated muscle cell differentiation |
GO_0007565 | Biological process | female pregnancy |
GO_0060056 | Biological process | mammary gland involution |
GO_0060416 | Biological process | response to growth hormone |
GO_0071320 | Biological process | cellular response to cAMP |
GO_0035556 | Biological process | intracellular signal transduction |
GO_0043568 | Biological process | positive regulation of insulin-like growth factor receptor signaling pathway |
GO_0048662 | Biological process | negative regulation of smooth muscle cell proliferation |
GO_0045668 | Biological process | negative regulation of osteoblast differentiation |
GO_0043569 | Biological process | negative regulation of insulin-like growth factor receptor signaling pathway |
GO_0051897 | Biological process | positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction |
GO_0030336 | Biological process | negative regulation of cell migration |
GO_0044342 | Biological process | type B pancreatic cell proliferation |
GO_0045926 | Biological process | negative regulation of growth |
GO_1904707 | Biological process | positive regulation of vascular associated smooth muscle cell proliferation |
GO_0071407 | Biological process | cellular response to organic cyclic compound |
GO_0043567 | Biological process | regulation of insulin-like growth factor receptor signaling pathway |
GO_0017148 | Biological process | negative regulation of translation |
GO_1904754 | Biological process | positive regulation of vascular associated smooth muscle cell migration |
GO_0048286 | Biological process | lung alveolus development |
GO_1901862 | Biological process | negative regulation of muscle tissue development |
GO_1904205 | Biological process | negative regulation of skeletal muscle hypertrophy |
GO_0005615 | Cellular component | extracellular space |
GO_0005576 | Cellular component | extracellular region |
GO_0042567 | Cellular component | insulin-like growth factor ternary complex |
GO_0005788 | Cellular component | endoplasmic reticulum lumen |
GO_0016942 | Cellular component | insulin-like growth factor binding protein complex |
GO_0001968 | Molecular function | fibronectin binding |
GO_0031994 | Molecular function | insulin-like growth factor I binding |
GO_0031995 | Molecular function | insulin-like growth factor II binding |
GO_0005515 | Molecular function | protein binding |
Gene name | IGFBP5 |
Protein name | Insulin like growth factor binding protein 5 IGFBP5 protein Insulin-like growth factor-binding protein 5 (IBP-5) (IGF-binding protein 5) (IGFBP-5) |
Synonyms | IBP5 |
Description | FUNCTION: IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. |
Accessions | C9JXX4 ENST00000449583.1 ENST00000233813.5 Q96HT5 Q8WV97 P24593 |