RASD2 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of RASD2 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of RASD2 at tissue level.

III. Associated gene sets

GO_0007165Biological processsignal transduction
GO_0001963Biological processsynaptic transmission, dopaminergic
GO_0051897Biological processpositive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
GO_0033235Biological processpositive regulation of protein sumoylation
GO_0043949Biological processregulation of cAMP-mediated signaling
GO_0007626Biological processlocomotory behavior
GO_0045202Cellular componentsynapse
GO_0005886Cellular componentplasma membrane
GO_0005525Molecular functionGTP binding
GO_0031681Molecular functionG-protein beta-subunit binding
GO_0003924Molecular functionGTPase activity

IV. Literature review

[source]
Gene nameRASD2
Protein nameGTP-binding protein Rhes (Ras homolog enriched in striatum) (Tumor endothelial marker 2)
SynonymsTEM2
DescriptionFUNCTION: GTPase signaling protein that binds to and hydrolyzes GTP. Regulates signaling pathways involving G-proteins-coupled receptor and heterotrimeric proteins such as GNB1, GNB2 and GNB3. May be involved in selected striatal competencies, mainly locomotor activity and motor coordination. .

AccessionsENST00000216127.5
Q96D21