MAZ report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0051897Biological processpositive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
GO_0010628Biological processpositive regulation of gene expression
GO_0008284Biological processpositive regulation of cell population proliferation
GO_0006367Biological processtranscription initiation at RNA polymerase II promoter
GO_0045893Biological processpositive regulation of DNA-templated transcription
GO_0030335Biological processpositive regulation of cell migration
GO_0000122Biological processnegative regulation of transcription by RNA polymerase II
GO_2001234Biological processnegative regulation of apoptotic signaling pathway
GO_0006369Biological processtermination of RNA polymerase II transcription
GO_0006357Biological processregulation of transcription by RNA polymerase II
GO_0005634Cellular componentnucleus
GO_0003723Molecular functionRNA binding
GO_0000978Molecular functionRNA polymerase II cis-regulatory region sequence-specific DNA binding
GO_0005515Molecular functionprotein binding
GO_0000981Molecular functionDNA-binding transcription factor activity, RNA polymerase II-specific
GO_0046872Molecular functionmetal ion binding

IV. Literature review

[source]
Gene nameMAZ
Protein nameMyc-associated zinc finger protein (MAZI) (Pur-1) (Purine-binding transcription factor) (Serum amyloid A-activating factor-1) (SAF-1) (Transcription factor Zif87) (ZF87) (Zinc finger protein 801)
MYC associated zinc finger protein (MYC-associated zinc finger protein (Purine-binding transcription factor), isoform CRA_a)
MYC associated zinc finger protein (MYC-associated zinc finger protein (Purine-binding transcription factor), isoform CRA_e)
MYC associated zinc finger protein
SynonymshCG_2039830
ZNF801
DescriptionFUNCTION: Transcriptional regulator, potentially with dual roles in transcription initiation and termination. .; FUNCTION: [Isoform 1]: Binds DNA and functions as a transcriptional activator . Binds to two G/A-rich sites, ME1a1 and ME1a2, within the MYC promoter having greater affinity for the former . Also binds to multiple G/C-rich sites within the promoter of the Sp1 family of transcription factors . .; FUNCTION: [Isoform 2]: Binds DNA and functions as a transcriptional activator . Inhibits MAZ isoform 1-mediated transcription . .; FUNCTION: [Isoform 3]: Binds DNA and functions as a transcriptional activator. .

AccessionsENST00000563402.1
ENST00000219782.11 [P56270-2]
H3BTS8
I3L4D3
ENST00000563012.1
ENST00000568544.5
I3L411
H3BQS2
I3L4Y2
ENST00000568282.1
ENST00000569978.1
P56270
ENST00000567444.5
ENST00000562337.5 [P56270-4]
H3BRC5
ENST00000561855.1
I3L2Z5
ENST00000322945.11 [P56270-1]
ENST00000568411.5
H3BPU3
ENST00000566906.6
ENST00000562557.5
ENST00000545521.5 [P56270-3]
H3BQI4
I3L0M3