Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| ciliated cell | 13 studies | 34% ± 12% | |
| astrocyte | 12 studies | 37% ± 14% | |
| oligodendrocyte | 10 studies | 26% ± 8% | |
| epithelial cell | 6 studies | 30% ± 10% | |
| basal cell | 5 studies | 32% ± 12% | |
| type I pneumocyte | 5 studies | 18% ± 2% | |
| hepatocyte | 4 studies | 38% ± 16% | |
| squamous epithelial cell | 3 studies | 27% ± 12% | |
| ependymal cell | 3 studies | 32% ± 17% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| brain | 4 studies | 23% ± 6% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| esophagus | 100% | 18215.23 | 1444 / 1445 | 99% | 52.85 | 182 / 183 |
| thymus | 100% | 27009.51 | 653 / 653 | 99% | 65.23 | 601 / 605 |
| prostate | 100% | 21406.06 | 245 / 245 | 99% | 45.24 | 498 / 502 |
| ovary | 100% | 13619.33 | 180 / 180 | 99% | 82.14 | 426 / 430 |
| brain | 99% | 10928.00 | 2626 / 2642 | 99% | 93.95 | 700 / 705 |
| intestine | 100% | 12756.39 | 964 / 966 | 98% | 44.67 | 516 / 527 |
| pancreas | 100% | 11128.54 | 327 / 328 | 98% | 46.52 | 174 / 178 |
| uterus | 100% | 12636.24 | 170 / 170 | 97% | 47.08 | 445 / 459 |
| liver | 100% | 14478.46 | 226 / 226 | 96% | 37.85 | 391 / 406 |
| bladder | 100% | 12228.43 | 21 / 21 | 96% | 52.12 | 484 / 504 |
| stomach | 100% | 9244.37 | 358 / 359 | 95% | 43.02 | 273 / 286 |
| breast | 98% | 11225.50 | 450 / 459 | 96% | 41.75 | 1073 / 1118 |
| kidney | 100% | 22097.85 | 89 / 89 | 90% | 47.46 | 815 / 901 |
| lung | 99% | 9091.46 | 573 / 578 | 90% | 33.74 | 1044 / 1155 |
| skin | 91% | 12403.63 | 1650 / 1809 | 77% | 27.46 | 364 / 472 |
| ureter | 0% | 0 | 0 / 0 | 100% | 42.84 | 1 / 1 |
| blood vessel | 100% | 20246.97 | 1333 / 1335 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 99% | 71.70 | 79 / 80 |
| adipose | 97% | 6773.49 | 1173 / 1204 | 0% | 0 | 0 / 0 |
| spleen | 97% | 6045.58 | 234 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 96% | 47.71 | 43 / 45 |
| heart | 86% | 4966.14 | 744 / 861 | 0% | 0 | 0 / 0 |
| adrenal gland | 26% | 940.16 | 66 / 258 | 58% | 34.80 | 133 / 230 |
| muscle | 2% | 72.66 | 17 / 803 | 0% | 0 | 0 / 0 |
| peripheral blood | 1% | 34.41 | 10 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0050772 | Biological process | positive regulation of axonogenesis |
| GO_0043547 | Biological process | positive regulation of GTPase activity |
| GO_0033689 | Biological process | negative regulation of osteoblast proliferation |
| GO_0051493 | Biological process | regulation of cytoskeleton organization |
| GO_0007162 | Biological process | negative regulation of cell adhesion |
| GO_0048812 | Biological process | neuron projection morphogenesis |
| GO_1904862 | Biological process | inhibitory synapse assembly |
| GO_0035556 | Biological process | intracellular signal transduction |
| GO_0043087 | Biological process | regulation of GTPase activity |
| GO_0030334 | Biological process | regulation of cell migration |
| GO_0051897 | Biological process | positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction |
| GO_0008360 | Biological process | regulation of cell shape |
| GO_0071526 | Biological process | semaphorin-plexin signaling pathway |
| GO_0035025 | Biological process | positive regulation of Rho protein signal transduction |
| GO_0043931 | Biological process | ossification involved in bone maturation |
| GO_0016477 | Biological process | cell migration |
| GO_0002116 | Cellular component | semaphorin receptor complex |
| GO_0005576 | Cellular component | extracellular region |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0017154 | Molecular function | semaphorin receptor activity |
| GO_0032794 | Molecular function | GTPase activating protein binding |
| GO_0004888 | Molecular function | transmembrane signaling receptor activity |
| GO_0030215 | Molecular function | semaphorin receptor binding |
| GO_0005096 | Molecular function | GTPase activator activity |
| GO_0005515 | Molecular function | protein binding |
| Gene name | PLXNB1 |
| Protein name | Plexin-B1 (Semaphorin receptor SEP) PLXNB1 protein Plexin B1 |
| Synonyms | PLXN5 SEP KIAA0407 |
| Description | FUNCTION: Receptor for SEMA4D . Plays a role in GABAergic synapse development (By similarity). Mediates SEMA4A- and SEMA4D-dependent inhibitory synapse development (By similarity). Plays a role in RHOA activation and subsequent changes of the actin cytoskeleton . Plays a role in axon guidance, invasive growth and cell migration . . |
| Accessions | A1A4U0 ENST00000358536.8 [O43157-1] ENST00000456774.5 [O43157-2] O43157 ENST00000296440.11 [O43157-1] A0A0B6XK48 ENST00000449094.5 [O43157-3] |