Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| astrocyte | 7 studies | 30% ± 10% | |
| GABAergic neuron | 6 studies | 39% ± 16% | |
| interneuron | 5 studies | 31% ± 16% | |
| oligodendrocyte precursor cell | 5 studies | 26% ± 10% | |
| fibroblast | 5 studies | 20% ± 3% | |
| endothelial cell | 4 studies | 37% ± 13% | |
| macrophage | 4 studies | 26% ± 6% | |
| neuron | 4 studies | 32% ± 14% | |
| epithelial cell | 4 studies | 27% ± 9% | |
| GABAergic interneuron | 3 studies | 22% ± 7% | |
| microglial cell | 3 studies | 22% ± 8% | |
| hepatocyte | 3 studies | 50% ± 20% | |
| B cell | 3 studies | 18% ± 2% | |
| glutamatergic neuron | 3 studies | 25% ± 9% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| brain | 5 studies | 25% ± 5% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| liver | 100% | 5521.85 | 226 / 226 | 100% | 42.16 | 405 / 406 |
| thymus | 100% | 3521.78 | 653 / 653 | 100% | 40.86 | 603 / 605 |
| kidney | 100% | 4411.31 | 89 / 89 | 99% | 34.75 | 896 / 901 |
| prostate | 100% | 2592.76 | 244 / 245 | 100% | 39.46 | 501 / 502 |
| breast | 100% | 1948.42 | 459 / 459 | 99% | 43.34 | 1111 / 1118 |
| pancreas | 100% | 4914.73 | 328 / 328 | 99% | 55.07 | 176 / 178 |
| stomach | 100% | 1532.50 | 359 / 359 | 99% | 44.38 | 282 / 286 |
| esophagus | 100% | 2087.25 | 1445 / 1445 | 98% | 47.28 | 180 / 183 |
| adrenal gland | 100% | 5800.24 | 258 / 258 | 97% | 61.23 | 223 / 230 |
| uterus | 100% | 2717.51 | 170 / 170 | 97% | 39.92 | 444 / 459 |
| lung | 100% | 4008.82 | 578 / 578 | 96% | 34.91 | 1113 / 1155 |
| intestine | 100% | 2943.42 | 966 / 966 | 96% | 44.44 | 504 / 527 |
| bladder | 100% | 2789.95 | 21 / 21 | 95% | 38.13 | 480 / 504 |
| ovary | 99% | 1244.36 | 179 / 180 | 90% | 22.39 | 388 / 430 |
| brain | 89% | 1233.99 | 2355 / 2642 | 99% | 35.84 | 699 / 705 |
| skin | 99% | 1700.98 | 1799 / 1809 | 80% | 17.88 | 378 / 472 |
| adipose | 100% | 1877.69 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| spleen | 100% | 3218.74 | 241 / 241 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 100% | 38.48 | 1 / 1 |
| blood vessel | 100% | 1850.34 | 1330 / 1335 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 99% | 38.86 | 79 / 80 |
| tonsil | 0% | 0 | 0 / 0 | 98% | 42.71 | 44 / 45 |
| lymph node | 0% | 0 | 0 / 0 | 97% | 44.30 | 28 / 29 |
| heart | 92% | 971.09 | 791 / 861 | 0% | 0 | 0 / 0 |
| peripheral blood | 55% | 1927.49 | 511 / 929 | 0% | 0 | 0 / 0 |
| muscle | 16% | 92.55 | 129 / 803 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0001525 | Biological process | angiogenesis |
| GO_0071466 | Biological process | cellular response to xenobiotic stimulus |
| GO_0030032 | Biological process | lamellipodium assembly |
| GO_0007165 | Biological process | signal transduction |
| GO_0051056 | Biological process | regulation of small GTPase mediated signal transduction |
| GO_0038095 | Biological process | Fc-epsilon receptor signaling pathway |
| GO_0030168 | Biological process | platelet activation |
| GO_0043087 | Biological process | regulation of GTPase activity |
| GO_0007264 | Biological process | small GTPase-mediated signal transduction |
| GO_0048010 | Biological process | vascular endothelial growth factor receptor signaling pathway |
| GO_0051897 | Biological process | positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction |
| GO_0008361 | Biological process | regulation of cell size |
| GO_0016477 | Biological process | cell migration |
| GO_0038096 | Biological process | Fc-gamma receptor signaling pathway involved in phagocytosis |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0005829 | Cellular component | cytosol |
| GO_0005737 | Cellular component | cytoplasm |
| GO_0005085 | Molecular function | guanyl-nucleotide exchange factor activity |
| GO_0005154 | Molecular function | epidermal growth factor receptor binding |
| GO_0046872 | Molecular function | metal ion binding |
| GO_0005515 | Molecular function | protein binding |
| GO_0001784 | Molecular function | phosphotyrosine residue binding |
| Gene name | VAV2 |
| Protein name | Guanine nucleotide exchange factor VAV2 (VAV-2) |
| Synonyms | |
| Description | FUNCTION: Guanine nucleotide exchange factor for the Rho family of Ras-related GTPases. Plays an important role in angiogenesis. Its recruitment by phosphorylated EPHA2 is critical for EFNA1-induced RAC1 GTPase activation and vascular endothelial cell migration and assembly (By similarity). . |
| Accessions | ENST00000371851.1 [P52735-2] ENST00000406606.7 [P52735-3] ENST00000371850.8 [P52735-1] P52735 |