Insufficient scRNA-seq data for expression of FSHR at single-cell level.
Insufficient scRNA-seq data for expression of FSHR at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
ovary | 98% | 81.73 | 177 / 180 | 0% | 0.03 | 2 / 430 |
heart | 64% | 10.10 | 551 / 861 | 0% | 0 | 0 / 0 |
bladder | 57% | 4.76 | 12 / 21 | 1% | 0.01 | 3 / 504 |
esophagus | 48% | 4.71 | 698 / 1445 | 0% | 0 | 0 / 183 |
intestine | 41% | 4.03 | 400 / 966 | 0% | 0 | 0 / 527 |
uterus | 38% | 2.61 | 65 / 170 | 0% | 0 | 0 / 459 |
blood vessel | 32% | 3.70 | 425 / 1335 | 0% | 0 | 0 / 0 |
kidney | 25% | 1.80 | 22 / 89 | 7% | 0.17 | 60 / 901 |
stomach | 27% | 2.59 | 96 / 359 | 1% | 0.01 | 2 / 286 |
lung | 25% | 1.70 | 146 / 578 | 0% | 0.00 | 3 / 1155 |
brain | 22% | 2.23 | 592 / 2642 | 0% | 0.00 | 1 / 705 |
adipose | 20% | 1.21 | 245 / 1204 | 0% | 0 | 0 / 0 |
prostate | 18% | 1.00 | 44 / 245 | 0% | 0.00 | 1 / 502 |
spleen | 16% | 0.82 | 38 / 241 | 0% | 0 | 0 / 0 |
adrenal gland | 10% | 0.53 | 26 / 258 | 1% | 0.04 | 2 / 230 |
breast | 8% | 0.39 | 38 / 459 | 0% | 0.01 | 2 / 1118 |
skin | 8% | 0.53 | 136 / 1809 | 0% | 0 | 0 / 472 |
thymus | 5% | 0.24 | 32 / 653 | 0% | 0.01 | 3 / 605 |
liver | 3% | 0.14 | 7 / 226 | 0% | 0 | 0 / 406 |
muscle | 3% | 0.14 | 22 / 803 | 0% | 0 | 0 / 0 |
peripheral blood | 3% | 0.12 | 25 / 929 | 0% | 0 | 0 / 0 |
pancreas | 1% | 0.04 | 4 / 328 | 0% | 0 | 0 / 178 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 45 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0008406 | Biological process | gonad development |
GO_0007283 | Biological process | spermatogenesis |
GO_0071372 | Biological process | cellular response to follicle-stimulating hormone stimulus |
GO_0042699 | Biological process | follicle-stimulating hormone signaling pathway |
GO_0010738 | Biological process | regulation of protein kinase A signaling |
GO_0007190 | Biological process | activation of adenylate cyclase activity |
GO_0007186 | Biological process | G protein-coupled receptor signaling pathway |
GO_0007189 | Biological process | adenylate cyclase-activating G protein-coupled receptor signaling pathway |
GO_0009755 | Biological process | hormone-mediated signaling pathway |
GO_0008584 | Biological process | male gonad development |
GO_0051897 | Biological process | positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction |
GO_0070374 | Biological process | positive regulation of ERK1 and ERK2 cascade |
GO_0008585 | Biological process | female gonad development |
GO_0007292 | Biological process | female gamete generation |
GO_0043235 | Cellular component | receptor complex |
GO_0005886 | Cellular component | plasma membrane |
GO_0016020 | Cellular component | membrane |
GO_0004963 | Molecular function | follicle-stimulating hormone receptor activity |
GO_0008528 | Molecular function | G protein-coupled peptide receptor activity |
GO_0005515 | Molecular function | protein binding |
Gene name | FSHR |
Protein name | FSHR Follicle-stimulating hormone receptor (FSH-R) (Follitropin receptor) Follicle-stimulating hormone receptor (Follitropin receptor) Follicle stimulating hormone receptor LRRNT domain-containing protein |
Synonyms | FSHR1 LGR1 |
Description | FUNCTION: G protein-coupled receptor for follitropin, the follicle-stimulating hormone. Through cAMP production activates the downstream PI3K-AKT and ERK1/ERK2 signaling pathways. . FUNCTION: G protein-coupled receptor for follitropin, the follicle-stimulating hormone . Through cAMP production activates the downstream PI3K-AKT and ERK1/ERK2 signaling pathways . . FUNCTION: G protein-coupled receptor for follitropin, the follicle-stimulating hormone. Through cAMP production activates the downstream PI3K-AKT and ERK1/ERK2 signaling pathways. . FUNCTION: G protein-coupled receptor for follitropin, the follicle-stimulating hormone. Through cAMP production activates the downstream PI3K-AKT and ERK1/ERK2 signaling pathways. . FUNCTION: G protein-coupled receptor for follitropin, the follicle-stimulating hormone. Through cAMP production activates the downstream PI3K-AKT and ERK1/ERK2 signaling pathways. . |
Accessions | F8WBM4 P23945 ENST00000304421.8 B6UV82 B6UV80 ENST00000406846.7 A0A1S0QI99 B4DXB5 B6UV79 C9JDA1 T2HV29 A0A1D5RMN4 A0A1S0QIA5 ENST00000454032.5 ENST00000419927.1 A0A0G3FIY1 |