Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| lung | 12 studies | 24% ± 6% | |
| peripheral blood | 10 studies | 24% ± 9% | |
| kidney | 7 studies | 24% ± 7% | |
| liver | 7 studies | 37% ± 23% | |
| bone marrow | 4 studies | 26% ± 8% | |
| intestine | 4 studies | 22% ± 8% | |
| adipose | 4 studies | 28% ± 11% | |
| brain | 3 studies | 20% ± 5% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| stomach | 100% | 5180.96 | 358 / 359 | 100% | 92.34 | 285 / 286 |
| liver | 100% | 21527.79 | 225 / 226 | 100% | 251.11 | 405 / 406 |
| thymus | 100% | 11047.58 | 653 / 653 | 99% | 224.42 | 599 / 605 |
| breast | 100% | 14165.56 | 459 / 459 | 99% | 87.55 | 1103 / 1118 |
| prostate | 99% | 4566.10 | 243 / 245 | 99% | 99.36 | 499 / 502 |
| lung | 100% | 8456.20 | 577 / 578 | 99% | 79.40 | 1138 / 1155 |
| kidney | 100% | 10062.30 | 89 / 89 | 98% | 149.87 | 886 / 901 |
| intestine | 100% | 5873.22 | 963 / 966 | 98% | 84.81 | 518 / 527 |
| ovary | 98% | 3745.18 | 177 / 180 | 99% | 73.95 | 427 / 430 |
| pancreas | 98% | 3978.99 | 321 / 328 | 99% | 71.01 | 177 / 178 |
| bladder | 100% | 5897.24 | 21 / 21 | 96% | 78.78 | 484 / 504 |
| esophagus | 94% | 3959.41 | 1356 / 1445 | 96% | 61.82 | 176 / 183 |
| skin | 99% | 6231.64 | 1795 / 1809 | 91% | 61.46 | 428 / 472 |
| uterus | 99% | 5039.14 | 169 / 170 | 87% | 51.04 | 399 / 459 |
| brain | 63% | 1509.44 | 1663 / 2642 | 100% | 65.50 | 702 / 705 |
| adrenal gland | 100% | 11438.05 | 258 / 258 | 56% | 29.73 | 129 / 230 |
| adipose | 100% | 15824.98 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 61.07 | 29 / 29 |
| spleen | 100% | 6075.09 | 241 / 241 | 0% | 0 | 0 / 0 |
| muscle | 99% | 6513.53 | 798 / 803 | 0% | 0 | 0 / 0 |
| peripheral blood | 99% | 9257.78 | 921 / 929 | 0% | 0 | 0 / 0 |
| blood vessel | 98% | 4528.88 | 1313 / 1335 | 0% | 0 | 0 / 0 |
| heart | 88% | 3808.70 | 759 / 861 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 87% | 35.25 | 39 / 45 |
| eye | 0% | 0 | 0 / 0 | 66% | 24.92 | 53 / 80 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0042542 | Biological process | response to hydrogen peroxide |
| GO_0032355 | Biological process | response to estradiol |
| GO_0051781 | Biological process | positive regulation of cell division |
| GO_0001657 | Biological process | ureteric bud development |
| GO_0061692 | Biological process | cellular detoxification of hydrogen peroxide |
| GO_0070542 | Biological process | response to fatty acid |
| GO_0009650 | Biological process | UV protection |
| GO_0001649 | Biological process | osteoblast differentiation |
| GO_0008203 | Biological process | cholesterol metabolic process |
| GO_0010193 | Biological process | response to ozone |
| GO_0042744 | Biological process | hydrogen peroxide catabolic process |
| GO_0010288 | Biological process | response to lead ion |
| GO_0032868 | Biological process | response to insulin |
| GO_0080184 | Biological process | response to phenylpropanoid |
| GO_0033189 | Biological process | response to vitamin A |
| GO_0014823 | Biological process | response to activity |
| GO_0045471 | Biological process | response to ethanol |
| GO_0071363 | Biological process | cellular response to growth factor stimulus |
| GO_0033197 | Biological process | response to vitamin E |
| GO_0014854 | Biological process | response to inactivity |
| GO_0046686 | Biological process | response to cadmium ion |
| GO_0055093 | Biological process | response to hyperoxia |
| GO_0020027 | Biological process | hemoglobin metabolic process |
| GO_0043066 | Biological process | negative regulation of apoptotic process |
| GO_0001666 | Biological process | response to hypoxia |
| GO_0006641 | Biological process | triglyceride metabolic process |
| GO_0009642 | Biological process | response to light intensity |
| GO_0033591 | Biological process | response to L-ascorbic acid |
| GO_0000302 | Biological process | response to reactive oxygen species |
| GO_0051897 | Biological process | positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction |
| GO_0009410 | Biological process | response to xenobiotic stimulus |
| GO_0009060 | Biological process | aerobic respiration |
| GO_0005778 | Cellular component | peroxisomal membrane |
| GO_0005576 | Cellular component | extracellular region |
| GO_0016020 | Cellular component | membrane |
| GO_0005739 | Cellular component | mitochondrion |
| GO_0070062 | Cellular component | extracellular exosome |
| GO_0032991 | Cellular component | protein-containing complex |
| GO_0062151 | Cellular component | catalase complex |
| GO_0005777 | Cellular component | peroxisome |
| GO_0034774 | Cellular component | secretory granule lumen |
| GO_0005925 | Cellular component | focal adhesion |
| GO_1904813 | Cellular component | ficolin-1-rich granule lumen |
| GO_0005829 | Cellular component | cytosol |
| GO_0005782 | Cellular component | peroxisomal matrix |
| GO_0005737 | Cellular component | cytoplasm |
| GO_0043231 | Cellular component | intracellular membrane-bounded organelle |
| GO_0019899 | Molecular function | enzyme binding |
| GO_0004096 | Molecular function | catalase activity |
| GO_0042803 | Molecular function | protein homodimerization activity |
| GO_0004046 | Molecular function | aminoacylase activity |
| GO_0042802 | Molecular function | identical protein binding |
| GO_0050661 | Molecular function | NADP binding |
| GO_0016209 | Molecular function | antioxidant activity |
| GO_0020037 | Molecular function | heme binding |
| GO_0046872 | Molecular function | metal ion binding |
| GO_0016684 | Molecular function | oxidoreductase activity, acting on peroxide as acceptor |
| Gene name | CAT |
| Protein name | Catalase Catalase (EC 1.11.1.6) |
| Synonyms | |
| Description | FUNCTION: Catalyzes the degradation of hydrogen peroxide (H(2)O(2)) generated by peroxisomal oxidases to water and oxygen, thereby protecting cells from the toxic effects of hydrogen peroxide . Promotes growth of cells including T-cells, B-cells, myeloid leukemia cells, melanoma cells, mastocytoma cells and normal and transformed fibroblast cells . . |
| Accessions | ENST00000241052.5 ENST00000650153.1 P04040 A0A3B3ITJ0 |