MYDGF | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
natural killer cell	33 studies	31% ± 8%	Explore
fibroblast	33 studies	42% ± 18%	Explore
endothelial cell	32 studies	38% ± 16%	Explore
macrophage	29 studies	38% ± 15%	Explore
plasma cell	27 studies	61% ± 25%	Explore
conventional dendritic cell	26 studies	34% ± 15%	Explore
T cell	22 studies	22% ± 5%	Explore
plasmacytoid dendritic cell	20 studies	48% ± 14%	Explore
CD4-positive, alpha-beta T cell	20 studies	25% ± 11%	Explore
CD8-positive, alpha-beta T cell	20 studies	28% ± 12%	Explore
pericyte	20 studies	31% ± 14%	Explore
classical monocyte	19 studies	32% ± 13%	Explore
non-classical monocyte	18 studies	34% ± 15%	Explore
connective tissue cell	18 studies	41% ± 16%	Explore
epithelial cell	18 studies	40% ± 23%	Explore
smooth muscle cell	18 studies	25% ± 8%	Explore
monocyte	17 studies	31% ± 11%	Explore
dendritic cell	15 studies	41% ± 22%	Explore
endothelial cell of lymphatic vessel	15 studies	41% ± 13%	Explore
basal cell	15 studies	38% ± 16%	Explore
regulatory T cell	15 studies	24% ± 10%	Explore
mature NK T cell	14 studies	27% ± 7%	Explore
CD16-positive, CD56-dim natural killer cell, human	13 studies	34% ± 8%	Explore
B cell	13 studies	24% ± 12%	Explore
plasmablast	12 studies	72% ± 21%	Explore
capillary endothelial cell	12 studies	31% ± 14%	Explore
myofibroblast cell	12 studies	35% ± 8%	Explore
gamma-delta T cell	12 studies	29% ± 10%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	11 studies	23% ± 6%	Explore
CD16-negative, CD56-bright natural killer cell, human	11 studies	35% ± 6%	Explore
endothelial cell of artery	11 studies	33% ± 15%	Explore
goblet cell	11 studies	33% ± 13%	Explore
vein endothelial cell	11 studies	31% ± 13%	Explore
endothelial cell of vascular tree	11 studies	28% ± 9%	Explore
mast cell	11 studies	20% ± 6%	Explore
CD8-positive, alpha-beta memory T cell	10 studies	25% ± 9%	Explore
secretory cell	10 studies	38% ± 12%	Explore
mucosal invariant T cell	10 studies	28% ± 6%	Explore
myeloid cell	10 studies	41% ± 14%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	9 studies	20% ± 3%	Explore
abnormal cell	9 studies	40% ± 17%	Explore
IgG plasma cell	9 studies	52% ± 15%	Explore
type I pneumocyte	8 studies	30% ± 12%	Explore
type II pneumocyte	8 studies	38% ± 18%	Explore
mesothelial cell	8 studies	42% ± 13%	Explore
IgA plasma cell	8 studies	52% ± 18%	Explore
CD4-positive, alpha-beta memory T cell	7 studies	30% ± 10%	Explore
club cell	7 studies	35% ± 15%	Explore
leukocyte	7 studies	28% ± 7%	Explore
effector memory CD8-positive, alpha-beta T cell	7 studies	28% ± 8%	Explore
progenitor cell	7 studies	39% ± 10%	Explore
ciliated cell	7 studies	40% ± 12%	Explore
memory B cell	7 studies	18% ± 4%	Explore
alveolar macrophage	6 studies	40% ± 10%	Explore
hematopoietic precursor cell	6 studies	38% ± 17%	Explore
naive B cell	6 studies	19% ± 4%	Explore
transit amplifying cell	6 studies	25% ± 7%	Explore
innate lymphoid cell	6 studies	30% ± 9%	Explore
T follicular helper cell	6 studies	19% ± 2%	Explore
respiratory goblet cell	5 studies	40% ± 24%	Explore
effector CD8-positive, alpha-beta T cell	5 studies	39% ± 13%	Explore
mononuclear phagocyte	5 studies	39% ± 18%	Explore
enterocyte	5 studies	26% ± 6%	Explore
effector memory CD4-positive, alpha-beta T cell	5 studies	32% ± 13%	Explore
neuron	5 studies	31% ± 16%	Explore
exhausted T cell	4 studies	34% ± 11%	Explore
enteroendocrine cell	4 studies	41% ± 15%	Explore
hematopoietic stem cell	4 studies	21% ± 4%	Explore
adventitial cell	4 studies	50% ± 10%	Explore
mucus secreting cell	4 studies	45% ± 18%	Explore
effector CD4-positive, alpha-beta T cell	4 studies	32% ± 9%	Explore
luminal hormone-sensing cell of mammary gland	4 studies	45% ± 7%	Explore
luminal cell of prostate epithelium	4 studies	35% ± 13%	Explore
oligodendrocyte precursor cell	4 studies	24% ± 5%	Explore
effector memory CD8-positive, alpha-beta T cell, terminally differentiated	4 studies	24% ± 6%	Explore
duct epithelial cell	3 studies	43% ± 1%	Explore
ionocyte	3 studies	23% ± 3%	Explore
pancreatic A cell	3 studies	66% ± 18%	Explore
type B pancreatic cell	3 studies	61% ± 21%	Explore
glomerular endothelial cell	3 studies	22% ± 5%	Explore
kidney distal convoluted tubule epithelial cell	3 studies	24% ± 6%	Explore
intestinal crypt stem cell	3 studies	28% ± 9%	Explore
neural crest cell	3 studies	28% ± 3%	Explore
kidney loop of Henle epithelial cell	3 studies	22% ± 5%	Explore
extravillous trophoblast	3 studies	90% ± 4%	Explore
placental villous trophoblast	3 studies	78% ± 6%	Explore
common myeloid progenitor	3 studies	41% ± 6%	Explore
lymphocyte	3 studies	40% ± 8%	Explore
precursor B cell	3 studies	22% ± 4%	Explore
microglial cell	3 studies	39% ± 11%	Explore
serous secreting cell	3 studies	44% ± 16%	Explore
erythroblast	3 studies	27% ± 14%	Explore
intermediate monocyte	3 studies	46% ± 11%	Explore
myoepithelial cell	3 studies	33% ± 15%	Explore
IgM plasma cell	3 studies	62% ± 6%	Explore
glutamatergic neuron	3 studies	27% ± 7%	Explore
granulocyte monocyte progenitor cell	3 studies	60% ± 15%	Explore
megakaryocyte-erythroid progenitor cell	3 studies	37% ± 24%	Explore
glial cell	3 studies	35% ± 18%	Explore
group 3 innate lymphoid cell	3 studies	31% ± 11%	Explore
T-helper 17 cell	3 studies	35% ± 17%	Explore
T-helper 1 cell	3 studies	35% ± 13%	Explore
double negative thymocyte	3 studies	36% ± 10%	Explore
progenitor cell of mammary luminal epithelium	3 studies	35% ± 8%	Explore
hepatocyte	3 studies	46% ± 30%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
lung	16 studies	35% ± 14%	Explore
peripheral blood	15 studies	28% ± 7%	Explore
intestine	11 studies	29% ± 12%	Explore
kidney	6 studies	29% ± 7%	Explore
liver	6 studies	27% ± 12%	Explore
brain	5 studies	28% ± 8%	Explore
placenta	4 studies	57% ± 25%	Explore
bone marrow	4 studies	26% ± 6%	Explore
uterus	4 studies	43% ± 18%	Explore
prostate	4 studies	28% ± 8%	Explore
lymph node	4 studies	30% ± 17%	Explore
breast	4 studies	34% ± 4%	Explore
pancreas	3 studies	60% ± 22%	Explore
eye	3 studies	24% ± 7%	Explore
adrenal gland	3 studies	25% ± 6%	Explore
skin	3 studies	21% ± 5%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
liver	100%	5794.85	226 / 226	100%	240.06	406 / 406
pancreas	100%	4688.10	328 / 328	100%	205.79	178 / 178
skin	100%	4249.89	1808 / 1809	100%	222.02	472 / 472
esophagus	100%	2184.39	1444 / 1445	100%	136.60	183 / 183
prostate	100%	3688.36	245 / 245	100%	324.39	501 / 502
uterus	100%	3087.78	170 / 170	100%	186.39	458 / 459
thymus	100%	3448.23	653 / 653	100%	169.97	603 / 605
stomach	100%	2995.63	359 / 359	100%	207.70	285 / 286
intestine	100%	2784.21	966 / 966	100%	241.77	525 / 527
ovary	100%	2873.77	180 / 180	100%	141.41	428 / 430
kidney	100%	2712.70	89 / 89	99%	149.91	896 / 901
lung	100%	4042.06	578 / 578	99%	197.12	1147 / 1155
breast	100%	3165.30	459 / 459	99%	186.76	1106 / 1118
bladder	100%	3197.05	21 / 21	99%	219.64	497 / 504
adrenal gland	100%	3732.00	258 / 258	98%	164.29	226 / 230
brain	97%	1324.68	2570 / 2642	100%	119.64	704 / 705
adipose	100%	3137.58	1204 / 1204	0%	0	0 / 0
eye	0%	0	0 / 0	100%	122.83	80 / 80
lymph node	0%	0	0 / 0	100%	203.28	29 / 29
spleen	100%	5029.66	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	156.81	45 / 45
ureter	0%	0	0 / 0	100%	185.97	1 / 1
blood vessel	100%	3216.58	1330 / 1335	0%	0	0 / 0
heart	97%	1773.88	839 / 861	0%	0	0 / 0
peripheral blood	95%	2071.69	886 / 929	0%	0	0 / 0
muscle	55%	440.05	438 / 803	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0006915	Biological process	apoptotic process
GO_0051897	Biological process	positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
GO_0001525	Biological process	angiogenesis
GO_0043066	Biological process	negative regulation of apoptotic process
GO_0001938	Biological process	positive regulation of endothelial cell proliferation
GO_0001934	Biological process	positive regulation of protein phosphorylation
GO_0043410	Biological process	positive regulation of MAPK cascade
GO_0045766	Biological process	positive regulation of angiogenesis
GO_0045944	Biological process	positive regulation of transcription by RNA polymerase II
GO_0005615	Cellular component	extracellular space
GO_0005788	Cellular component	endoplasmic reticulum lumen
GO_0005783	Cellular component	endoplasmic reticulum
GO_0005793	Cellular component	endoplasmic reticulum-Golgi intermediate compartment
GO_0005794	Cellular component	Golgi apparatus
GO_0005515	Molecular function	protein binding

IV. Literature review

[source]

Gene name	MYDGF
Protein name	Myeloid-derived growth factor (MYDGF) Myeloid derived growth factor
Synonyms	C19orf10
Description	FUNCTION: Bone marrow-derived monocyte and paracrine-acting protein that promotes cardiac myocyte survival and adaptive angiogenesis for cardiac protection and/or repair after myocardial infarction (MI). Stimulates endothelial cell proliferation through a MAPK1/3-, STAT3- and CCND1-mediated signaling pathway. Inhibits cardiac myocyte apoptosis in a PI3K/AKT-dependent signaling pathway (By similarity). Involved in endothelial cell proliferation and angiogenesis . .
Accessions	M0QXF7 ENST00000262947.8 M0QYN0 ENST00000599761.5 ENST00000599630.1 Q969H8

MYDGF report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review