Name | Number of supported studies | Average coverage | |
---|---|---|---|
type B pancreatic cell | 4 studies | 96% ± 3% |
Name | Number of supported studies | Average coverage | |
---|---|---|---|
pancreas | 3 studies | 64% ± 33% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
pancreas | 100% | 87756.00 | 327 / 328 | 67% | 1589.63 | 120 / 178 |
adrenal gland | 82% | 63.26 | 212 / 258 | 20% | 8.28 | 45 / 230 |
liver | 75% | 14.23 | 169 / 226 | 0% | 2.65 | 1 / 406 |
spleen | 71% | 25.49 | 171 / 241 | 0% | 0 | 0 / 0 |
ovary | 61% | 7.79 | 110 / 180 | 0% | 0 | 0 / 430 |
stomach | 59% | 8.95 | 211 / 359 | 0% | 0 | 0 / 286 |
uterus | 56% | 8.09 | 95 / 170 | 0% | 0.11 | 1 / 459 |
kidney | 55% | 7.46 | 49 / 89 | 0% | 0 | 0 / 901 |
prostate | 52% | 9.00 | 128 / 245 | 0% | 0 | 0 / 502 |
intestine | 47% | 7.92 | 456 / 966 | 2% | 61.87 | 12 / 527 |
bladder | 48% | 4.24 | 10 / 21 | 0% | 0.16 | 1 / 504 |
esophagus | 47% | 7.87 | 678 / 1445 | 0% | 0 | 0 / 183 |
thymus | 40% | 8.23 | 264 / 653 | 0% | 0 | 0 / 605 |
blood vessel | 39% | 15.97 | 514 / 1335 | 0% | 0 | 0 / 0 |
skin | 38% | 6.29 | 686 / 1809 | 0% | 0 | 0 / 472 |
lung | 38% | 5.27 | 217 / 578 | 0% | 0.17 | 1 / 1155 |
brain | 37% | 7.01 | 974 / 2642 | 0% | 0 | 0 / 705 |
breast | 37% | 12.80 | 168 / 459 | 0% | 0.20 | 1 / 1118 |
adipose | 36% | 27.38 | 438 / 1204 | 0% | 0 | 0 / 0 |
peripheral blood | 33% | 4.79 | 309 / 929 | 0% | 0 | 0 / 0 |
heart | 32% | 7.86 | 276 / 861 | 0% | 0 | 0 / 0 |
muscle | 31% | 3.93 | 251 / 803 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 45 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_1902952 | Biological process | positive regulation of dendritic spine maintenance |
GO_0051247 | Biological process | positive regulation of protein metabolic process |
GO_0010976 | Biological process | positive regulation of neuron projection development |
GO_0046889 | Biological process | positive regulation of lipid biosynthetic process |
GO_0046631 | Biological process | alpha-beta T cell activation |
GO_0007267 | Biological process | cell-cell signaling |
GO_0051092 | Biological process | positive regulation of NF-kappaB transcription factor activity |
GO_0045922 | Biological process | negative regulation of fatty acid metabolic process |
GO_0045861 | Biological process | negative regulation of proteolysis |
GO_1900273 | Biological process | positive regulation of long-term synaptic potentiation |
GO_0010750 | Biological process | positive regulation of nitric oxide mediated signal transduction |
GO_0051897 | Biological process | positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction |
GO_0050708 | Biological process | regulation of protein secretion |
GO_0006006 | Biological process | glucose metabolic process |
GO_0042177 | Biological process | negative regulation of protein catabolic process |
GO_0006953 | Biological process | acute-phase response |
GO_0010629 | Biological process | negative regulation of gene expression |
GO_0038060 | Biological process | nitric oxide-cGMP-mediated signaling |
GO_0010628 | Biological process | positive regulation of gene expression |
GO_0032880 | Biological process | regulation of protein localization |
GO_0090277 | Biological process | positive regulation of peptide hormone secretion |
GO_0050709 | Biological process | negative regulation of protein secretion |
GO_1903427 | Biological process | negative regulation of reactive oxygen species biosynthetic process |
GO_0042060 | Biological process | wound healing |
GO_0007186 | Biological process | G protein-coupled receptor signaling pathway |
GO_0045818 | Biological process | negative regulation of glycogen catabolic process |
GO_0006355 | Biological process | regulation of DNA-templated transcription |
GO_0001819 | Biological process | positive regulation of cytokine production |
GO_1903076 | Biological process | regulation of protein localization to plasma membrane |
GO_0060267 | Biological process | positive regulation of respiratory burst |
GO_0045821 | Biological process | positive regulation of glycolytic process |
GO_0033861 | Biological process | negative regulation of NAD(P)H oxidase activity |
GO_0032148 | Biological process | activation of protein kinase B activity |
GO_0055089 | Biological process | fatty acid homeostasis |
GO_0050714 | Biological process | positive regulation of protein secretion |
GO_0045597 | Biological process | positive regulation of cell differentiation |
GO_0008286 | Biological process | insulin receptor signaling pathway |
GO_0046628 | Biological process | positive regulation of insulin receptor signaling pathway |
GO_0008284 | Biological process | positive regulation of cell population proliferation |
GO_0042311 | Biological process | vasodilation |
GO_0060266 | Biological process | negative regulation of respiratory burst involved in inflammatory response |
GO_0046326 | Biological process | positive regulation of glucose import |
GO_0045721 | Biological process | negative regulation of gluconeogenesis |
GO_0030307 | Biological process | positive regulation of cell growth |
GO_1902176 | Biological process | negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway |
GO_1990535 | Biological process | neuron projection maintenance |
GO_0043410 | Biological process | positive regulation of MAPK cascade |
GO_0002674 | Biological process | negative regulation of acute inflammatory response |
GO_0045725 | Biological process | positive regulation of glycogen biosynthetic process |
GO_0048167 | Biological process | regulation of synaptic plasticity |
GO_0030335 | Biological process | positive regulation of cell migration |
GO_0090336 | Biological process | positive regulation of brown fat cell differentiation |
GO_0050995 | Biological process | negative regulation of lipid catabolic process |
GO_0031954 | Biological process | positive regulation of protein autophosphorylation |
GO_0050890 | Biological process | cognition |
GO_2000252 | Biological process | negative regulation of feeding behavior |
GO_0051000 | Biological process | positive regulation of nitric-oxide synthase activity |
GO_0006521 | Biological process | regulation of cellular amino acid metabolic process |
GO_0022898 | Biological process | regulation of transmembrane transporter activity |
GO_0045840 | Biological process | positive regulation of mitotic nuclear division |
GO_0042593 | Biological process | glucose homeostasis |
GO_1900182 | Biological process | positive regulation of protein localization to nucleus |
GO_0033116 | Cellular component | endoplasmic reticulum-Golgi intermediate compartment membrane |
GO_0005788 | Cellular component | endoplasmic reticulum lumen |
GO_0031904 | Cellular component | endosome lumen |
GO_0005576 | Cellular component | extracellular region |
GO_0005615 | Cellular component | extracellular space |
GO_0034774 | Cellular component | secretory granule lumen |
GO_0000139 | Cellular component | Golgi membrane |
GO_0005796 | Cellular component | Golgi lumen |
GO_0030133 | Cellular component | transport vesicle |
GO_0042802 | Molecular function | identical protein binding |
GO_0005179 | Molecular function | hormone activity |
GO_0002020 | Molecular function | protease binding |
GO_0005515 | Molecular function | protein binding |
GO_0005158 | Molecular function | insulin receptor binding |
GO_0005159 | Molecular function | insulin-like growth factor receptor binding |
Gene name | INS |
Protein name | Insulin [Cleaved into: Insulin B chain; Insulin A chain] INS Insulin |
Synonyms | |
Description | FUNCTION: Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. FUNCTION: Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. . FUNCTION: Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. . FUNCTION: Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. . |
Accessions | ENST00000381330.5 [P01308-1] ENST00000397262.5 [P01308-1] A0A9E9AQX1 F6MZK5 C9JNR5 P01308 ENST00000250971.7 [P01308-1] I3WAC9 A6XGL2 ENST00000512523.1 ENST00000421783.1 |