GCNT2 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0010718Biological processpositive regulation of epithelial to mesenchymal transition
GO_0034116Biological processpositive regulation of heterotypic cell-cell adhesion
GO_0051897Biological processpositive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
GO_0008284Biological processpositive regulation of cell population proliferation
GO_0007275Biological processmulticellular organism development
GO_0030335Biological processpositive regulation of cell migration
GO_0010608Biological processpost-transcriptional regulation of gene expression
GO_0036438Biological processmaintenance of lens transparency
GO_0007179Biological processtransforming growth factor beta receptor signaling pathway
GO_0006024Biological processglycosaminoglycan biosynthetic process
GO_0070374Biological processpositive regulation of ERK1 and ERK2 cascade
GO_0010812Biological processnegative regulation of cell-substrate adhesion
GO_0006486Biological processprotein glycosylation
GO_0000139Cellular componentGolgi membrane
GO_0005794Cellular componentGolgi apparatus
GO_0016020Cellular componentmembrane
GO_0008375Molecular functionacetylglucosaminyltransferase activity
GO_0008109Molecular functionN-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity

IV. Literature review

[source]
Gene nameGCNT2
Protein nameGlucosaminyl (N-acetyl) transferase 2 (I blood group)
N-acetyllactosaminide beta-1,6-N-acetylglucosaminyl-transferase (N-acetylglucosaminyltransferase) (EC 2.4.1.150) (I-branching enzyme) (IGNT)
SynonymsGCNT5
II
NACGT1
DescriptionFUNCTION: Branching enzyme that converts linear into branched poly-N-acetyllactosaminoglycans. Introduces the blood group I antigen during embryonic development. It is closely associated with the development and maturation of erythroid cells. .; FUNCTION: [Isoform C]: Determines the expression of the blood group I antigen in erythrocytes. .

AccessionsQ8N0V5
B7ZBL3
ENST00000379597.7 [Q8N0V5-1]
ENST00000644083.4 [Q8N0V5-1]
ENST00000642698.1 [Q8N0V5-1]
ENST00000643503.2 [Q8N0V5-2]
ENST00000410107.5
ENST00000495262.7 [Q8N0V5-1]
ENST00000265012.5 [Q8N0V5-3]
ENST00000316170.9 [Q8N0V5-2]