positive regulation of epithelial to mesenchymal transition

I. Involved cell-cell interactions

[source]
Interactors
Protein name
Directionality
Classification
1TGFB1-ACVR1+TGFBR2TGFB1_HUMAN - Ligand-ReceptorSignaling by Transforming growth factor
2TGFB1-TGFBR1+TGFBR2TGFB1_HUMAN - Ligand-ReceptorSignaling by Transforming growth factor
3TGFB2-ACVR1+TGFBR2TGFB2_HUMAN - Ligand-ReceptorSignaling by Transforming growth factor
4TGFB2-TGFBR1+TGFBR2TGFB2_HUMAN - Ligand-ReceptorSignaling by Transforming growth factor
5TGFB3-ACVR1+TGFBR2TGFB3_HUMAN - Ligand-ReceptorSignaling by Transforming growth factor
6TGFB3-TGFBR1+TGFBR2TGFB3_HUMAN - Ligand-ReceptorSignaling by Transforming growth factor

II. Literature review

[source]
Namepositive regulation of epithelial to mesenchymal transition
IDGO_0010718
collection_id

Biological process

Description

Any process that increases the rate, frequency, or extent of epithelial to mesenchymal transition. Epithelial to mesenchymal transition is where an epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell.

External URL
Genes
ADAM8PTK2OLFM1AXIN2AGTTCF7L2TGFBR2TIAM1TWIST1WWTR1IL1BURS00002C6949_9606SNAI1SMAD4TBX20TGFB3URS0000170CF4_9606FOXC1BMP7MTORBAMBIDAB2RGCCLEF1LOXL2MAD2L2ALX1PDPNTGFB1IL6FERMT2CTNNB1MDKTNXBHDAC2GCNT2BMP2TGFB2CRB2tenascin-x_humanTGFB1I1SMAD2BCL9LBMP4GLIPR2COL1A1ZNF703URS000039ED8D_9606URS0000298BA3_9606TGFBR1SERPINB3EZH2SDCBPLRG1KDM1ASMAD3