COL1A1 | OmnibusX

Name	Number of supported studies	Average coverage
fibroblast	46 studies	64% ± 26%	Explore
smooth muscle cell	26 studies	45% ± 23%	Explore
pericyte	23 studies	44% ± 26%	Explore
connective tissue cell	18 studies	66% ± 26%	Explore
myofibroblast cell	14 studies	70% ± 22%	Explore
mesothelial cell	10 studies	63% ± 22%	Explore
endothelial cell	6 studies	20% ± 5%	Explore
adventitial cell	5 studies	62% ± 15%	Explore
neural crest cell	3 studies	34% ± 8%	Explore
macrophage	3 studies	30% ± 17%	Explore
epithelial cell	3 studies	38% ± 12%	Explore
B cell	3 studies	23% ± 7%	Explore
glial cell	3 studies	26% ± 5%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
intestine	5 studies	47% ± 7%	Explore
lung	5 studies	33% ± 15%	Explore
uterus	4 studies	27% ± 2%	Explore
heart	3 studies	24% ± 5%	Explore
skin	3 studies	38% ± 14%	Explore
adipose	3 studies	37% ± 17%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
breast	92%	53103.14	421 / 459	92%	2848.90	1030 / 1118
ovary	100%	129590.28	180 / 180	76%	1617.31	327 / 430
bladder	100%	92960.24	21 / 21	66%	1156.18	335 / 504
lung	88%	48582.30	506 / 578	78%	1291.11	901 / 1155
intestine	94%	57177.96	904 / 966	72%	1133.12	379 / 527
stomach	82%	30344.27	296 / 359	81%	1343.82	232 / 286
uterus	100%	174553.06	170 / 170	57%	1191.85	263 / 459
esophagus	72%	20888.12	1034 / 1445	80%	1734.32	146 / 183
skin	88%	239243.78	1593 / 1809	59%	783.64	278 / 472
prostate	99%	50957.60	243 / 245	16%	92.99	81 / 502
pancreas	16%	6364.63	53 / 328	90%	2782.47	160 / 178
blood vessel	100%	75233.15	1331 / 1335	0%	0	0 / 0
adipose	92%	77126.34	1102 / 1204	0%	0	0 / 0
thymus	66%	15785.34	432 / 653	25%	275.98	153 / 605
adrenal gland	60%	11356.34	156 / 258	9%	111.23	21 / 230
spleen	63%	13701.67	151 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	62%	1019.97	28 / 45
kidney	37%	9028.40	33 / 89	24%	250.81	215 / 901
heart	57%	26602.69	488 / 861	0%	0	0 / 0
lymph node	0%	0	0 / 0	34%	321.30	10 / 29
liver	11%	2980.94	24 / 226	20%	146.88	80 / 406
muscle	6%	1654.51	49 / 803	0%	0	0 / 0
brain	0%	22.72	3 / 2642	4%	63.87	30 / 705
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
eye	0%	0	0 / 0	0%	0	0 / 80
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
peripheral blood	0%	0	0 / 929	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

III. Associated gene sets

GO_0071300	Biological process	cellular response to retinoic acid
GO_0042542	Biological process	response to hydrogen peroxide
GO_0060346	Biological process	bone trabecula formation
GO_0007601	Biological process	visual perception
GO_0007605	Biological process	sensory perception of sound
GO_0071333	Biological process	cellular response to glucose stimulus
GO_0032355	Biological process	response to estradiol
GO_0071560	Biological process	cellular response to transforming growth factor beta stimulus
GO_0071260	Biological process	cellular response to mechanical stimulus
GO_0090263	Biological process	positive regulation of canonical Wnt signaling pathway
GO_0071364	Biological process	cellular response to epidermal growth factor stimulus
GO_0001649	Biological process	osteoblast differentiation
GO_0001957	Biological process	intramembranous ossification
GO_0030198	Biological process	extracellular matrix organization
GO_0032868	Biological process	response to insulin
GO_0038063	Biological process	collagen-activated tyrosine kinase receptor signaling pathway
GO_0001958	Biological process	endochondral ossification
GO_0071356	Biological process	cellular response to tumor necrosis factor
GO_0051591	Biological process	response to cAMP
GO_0055093	Biological process	response to hyperoxia
GO_0045893	Biological process	positive regulation of DNA-templated transcription
GO_0030335	Biological process	positive regulation of cell migration
GO_0048706	Biological process	embryonic skeletal system development
GO_0034504	Biological process	protein localization to nucleus
GO_0071230	Biological process	cellular response to amino acid stimulus
GO_0001568	Biological process	blood vessel development
GO_0034505	Biological process	tooth mineralization
GO_0010718	Biological process	positive regulation of epithelial to mesenchymal transition
GO_0043589	Biological process	skin morphogenesis
GO_0048545	Biological process	response to steroid hormone
GO_0001501	Biological process	skeletal system development
GO_0015031	Biological process	protein transport
GO_0009612	Biological process	response to mechanical stimulus
GO_0030199	Biological process	collagen fibril organization
GO_0001503	Biological process	ossification
GO_1902618	Biological process	cellular response to fluoride
GO_0009410	Biological process	response to xenobiotic stimulus
GO_0071306	Biological process	cellular response to vitamin E
GO_0043588	Biological process	skin development
GO_0060325	Biological process	face morphogenesis
GO_0044344	Biological process	cellular response to fibroblast growth factor stimulus
GO_0060351	Biological process	cartilage development involved in endochondral bone morphogenesis
GO_0010812	Biological process	negative regulation of cell-substrate adhesion
GO_0032964	Biological process	collagen biosynthetic process
GO_0005615	Cellular component	extracellular space
GO_0005576	Cellular component	extracellular region
GO_0005584	Cellular component	collagen type I trimer
GO_0062023	Cellular component	collagen-containing extracellular matrix
GO_0005788	Cellular component	endoplasmic reticulum lumen
GO_0005737	Cellular component	cytoplasm
GO_0030141	Cellular component	secretory granule
GO_0030020	Molecular function	extracellular matrix structural constituent conferring tensile strength
GO_0042802	Molecular function	identical protein binding
GO_0002020	Molecular function	protease binding
GO_0048407	Molecular function	platelet-derived growth factor binding
GO_0046872	Molecular function	metal ion binding
GO_0005515	Molecular function	protein binding

Gene name	COL1A1
Protein name	Collagen alpha-1(I) chain preproprotein Collagen alpha-1(I) chain (Alpha-1 type I collagen) Collagen type I alpha 1 Type I collagen alpha 1 chain Alpha 1 collagen Alternative protein COL1A1 Type I collagen alpha 1(I) chain COL1A1 Type I procollagen alpha 1 chain Collagen alpha 1(I) chain Collagen type I alpha 1 chain
Synonyms
Description	FUNCTION: Type I collagen is a member of group I collagen (fibrillar forming collagen).
Accessions	Q16053 ENST00000507689.1 I3L3H7 H9C5C5 O00604 Q9UNF2 P02452 Q9UMA6 L0R6F3 Q9UE86 Q6LAN8 T1RTD8 ENST00000225964.10

COL1A1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review