Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| basal cell | 12 studies | 45% ± 23% | |
| epithelial cell | 6 studies | 44% ± 26% | |
| respiratory goblet cell | 6 studies | 68% ± 9% | |
| club cell | 5 studies | 80% ± 6% | |
| deuterosomal cell | 4 studies | 33% ± 11% | |
| secretory cell | 4 studies | 75% ± 21% | |
| duct epithelial cell | 3 studies | 52% ± 16% | |
| squamous epithelial cell | 3 studies | 43% ± 20% | |
| ciliated cell | 3 studies | 47% ± 8% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| esophagus | 41% | 7831.36 | 591 / 1445 | 51% | 125.78 | 93 / 183 |
| skin | 67% | 417.09 | 1213 / 1809 | 8% | 10.76 | 36 / 472 |
| tonsil | 0% | 0 | 0 / 0 | 62% | 135.51 | 28 / 45 |
| uterus | 4% | 547.58 | 6 / 170 | 58% | 318.93 | 268 / 459 |
| lung | 15% | 117.41 | 89 / 578 | 32% | 51.57 | 367 / 1155 |
| prostate | 40% | 257.09 | 97 / 245 | 3% | 0.55 | 13 / 502 |
| bladder | 5% | 3.90 | 1 / 21 | 27% | 45.15 | 136 / 504 |
| pancreas | 0% | 0 | 0 / 328 | 22% | 12.92 | 39 / 178 |
| intestine | 0% | 0.65 | 4 / 966 | 5% | 8.17 | 25 / 527 |
| breast | 2% | 2.42 | 9 / 459 | 1% | 1.66 | 14 / 1118 |
| stomach | 1% | 24.34 | 4 / 359 | 2% | 1.72 | 5 / 286 |
| ovary | 1% | 1.47 | 2 / 180 | 1% | 0.32 | 3 / 430 |
| liver | 0% | 0.62 | 1 / 226 | 1% | 0.83 | 5 / 406 |
| thymus | 1% | 2.62 | 6 / 653 | 0% | 0 | 0 / 605 |
| adipose | 1% | 2.47 | 11 / 1204 | 0% | 0 | 0 / 0 |
| adrenal gland | 0% | 0.40 | 1 / 258 | 0% | 0.17 | 1 / 230 |
| muscle | 1% | 1.50 | 6 / 803 | 0% | 0 | 0 / 0 |
| peripheral blood | 1% | 25.67 | 5 / 929 | 0% | 0 | 0 / 0 |
| blood vessel | 0% | 1.33 | 6 / 1335 | 0% | 0 | 0 / 0 |
| brain | 0% | 0.37 | 8 / 2642 | 0% | 0.05 | 1 / 705 |
| spleen | 0% | 1.09 | 1 / 241 | 0% | 0 | 0 / 0 |
| heart | 0% | 0.28 | 3 / 861 | 0% | 0 | 0 / 0 |
| kidney | 0% | 0 | 0 / 89 | 0% | 0.44 | 3 / 901 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0035425 | Biological process | autocrine signaling |
| GO_0010951 | Biological process | negative regulation of endopeptidase activity |
| GO_0038001 | Biological process | paracrine signaling |
| GO_0043086 | Biological process | negative regulation of catalytic activity |
| GO_0043508 | Biological process | negative regulation of JUN kinase activity |
| GO_0046718 | Biological process | symbiont entry into host cell |
| GO_0045861 | Biological process | negative regulation of proteolysis |
| GO_0030335 | Biological process | positive regulation of cell migration |
| GO_0010466 | Biological process | negative regulation of peptidase activity |
| GO_0010718 | Biological process | positive regulation of epithelial to mesenchymal transition |
| GO_0008284 | Biological process | positive regulation of cell population proliferation |
| GO_0010950 | Biological process | positive regulation of endopeptidase activity |
| GO_0035578 | Cellular component | azurophil granule lumen |
| GO_0005615 | Cellular component | extracellular space |
| GO_0005576 | Cellular component | extracellular region |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0031410 | Cellular component | cytoplasmic vesicle |
| GO_0070062 | Cellular component | extracellular exosome |
| GO_0005829 | Cellular component | cytosol |
| GO_0005737 | Cellular component | cytoplasm |
| GO_0031982 | Cellular component | vesicle |
| GO_0005634 | Cellular component | nucleus |
| GO_0004869 | Molecular function | cysteine-type endopeptidase inhibitor activity |
| GO_0004867 | Molecular function | serine-type endopeptidase inhibitor activity |
| GO_0001618 | Molecular function | virus receptor activity |
| GO_0002020 | Molecular function | protease binding |
| Gene name | SERPINB3 |
| Protein name | Serpin B3 (Protein T4-A) (Squamous cell carcinoma antigen 1) (SCCA-1) |
| Synonyms | SCCA SCCA1 |
| Description | FUNCTION: May act as a papain-like cysteine protease inhibitor to modulate the host immune response against tumor cells. Also functions as an inhibitor of UV-induced apoptosis via suppression of the activity of c-Jun NH(2)-terminal kinase (JNK1). . |
| Accessions | P29508 ENST00000283752.10 [P29508-1] ENST00000332821.8 [P29508-2] |
