Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| vein endothelial cell | 10 studies | 34% ± 10% | |
| endothelial cell | 9 studies | 24% ± 7% | |
| platelet | 6 studies | 31% ± 12% | |
| endothelial cell of vascular tree | 5 studies | 21% ± 2% | |
| endothelial cell of artery | 4 studies | 22% ± 7% | |
| megakaryocyte | 3 studies | 54% ± 7% |
Insufficient scRNA-seq data for expression of SELP at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| prostate | 99% | 1276.99 | 243 / 245 | 98% | 13.50 | 494 / 502 |
| thymus | 97% | 793.19 | 635 / 653 | 85% | 9.62 | 514 / 605 |
| lung | 100% | 1867.95 | 578 / 578 | 78% | 6.86 | 906 / 1155 |
| breast | 100% | 1952.04 | 457 / 459 | 73% | 8.88 | 821 / 1118 |
| kidney | 97% | 858.81 | 86 / 89 | 71% | 7.44 | 644 / 901 |
| esophagus | 95% | 723.37 | 1377 / 1445 | 62% | 6.39 | 113 / 183 |
| bladder | 95% | 784.33 | 20 / 21 | 57% | 4.48 | 288 / 504 |
| intestine | 93% | 662.36 | 902 / 966 | 55% | 4.21 | 289 / 527 |
| uterus | 99% | 1320.52 | 168 / 170 | 42% | 2.82 | 195 / 459 |
| stomach | 68% | 411.71 | 245 / 359 | 66% | 6.33 | 189 / 286 |
| adrenal gland | 76% | 274.39 | 195 / 258 | 53% | 3.56 | 123 / 230 |
| pancreas | 21% | 59.22 | 70 / 328 | 89% | 12.64 | 159 / 178 |
| ureter | 0% | 0 | 0 / 0 | 100% | 2.50 | 1 / 1 |
| adipose | 100% | 1842.18 | 1203 / 1204 | 0% | 0 | 0 / 0 |
| blood vessel | 91% | 1018.94 | 1220 / 1335 | 0% | 0 | 0 / 0 |
| skin | 45% | 177.97 | 807 / 1809 | 46% | 3.59 | 218 / 472 |
| lymph node | 0% | 0 | 0 / 0 | 90% | 7.87 | 26 / 29 |
| heart | 87% | 590.92 | 747 / 861 | 0% | 0 | 0 / 0 |
| ovary | 55% | 281.81 | 99 / 180 | 22% | 0.94 | 96 / 430 |
| tonsil | 0% | 0 | 0 / 0 | 73% | 7.19 | 33 / 45 |
| peripheral blood | 69% | 429.30 | 643 / 929 | 0% | 0 | 0 / 0 |
| spleen | 52% | 151.60 | 125 / 241 | 0% | 0 | 0 / 0 |
| liver | 19% | 47.19 | 43 / 226 | 24% | 1.43 | 96 / 406 |
| eye | 0% | 0 | 0 / 0 | 21% | 0.72 | 17 / 80 |
| muscle | 17% | 49.20 | 135 / 803 | 0% | 0 | 0 / 0 |
| brain | 1% | 2.94 | 17 / 2642 | 2% | 0.13 | 13 / 705 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0033623 | Biological process | regulation of integrin activation |
| GO_0006954 | Biological process | inflammatory response |
| GO_0034097 | Biological process | response to cytokine |
| GO_0050829 | Biological process | defense response to Gram-negative bacterium |
| GO_0007155 | Biological process | cell adhesion |
| GO_1903238 | Biological process | positive regulation of leukocyte tethering or rolling |
| GO_0016339 | Biological process | calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules |
| GO_0050901 | Biological process | leukocyte tethering or rolling |
| GO_0002687 | Biological process | positive regulation of leukocyte migration |
| GO_0051897 | Biological process | positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction |
| GO_0010572 | Biological process | positive regulation of platelet activation |
| GO_0098609 | Biological process | cell-cell adhesion |
| GO_0007157 | Biological process | heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules |
| GO_0032496 | Biological process | response to lipopolysaccharide |
| GO_0007159 | Biological process | leukocyte cell-cell adhesion |
| GO_0005615 | Cellular component | extracellular space |
| GO_0009897 | Cellular component | external side of plasma membrane |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0031088 | Cellular component | platelet dense granule membrane |
| GO_0031092 | Cellular component | platelet alpha granule membrane |
| GO_0008201 | Molecular function | heparin binding |
| GO_0033691 | Molecular function | sialic acid binding |
| GO_0005178 | Molecular function | integrin binding |
| GO_0042806 | Molecular function | fucose binding |
| GO_0070492 | Molecular function | oligosaccharide binding |
| GO_0043208 | Molecular function | glycosphingolipid binding |
| GO_0048306 | Molecular function | calcium-dependent protein binding |
| GO_0001530 | Molecular function | lipopolysaccharide binding |
| GO_0005509 | Molecular function | calcium ion binding |
| GO_0005515 | Molecular function | protein binding |
| Gene name | SELP |
| Protein name | P-selectin (CD62 antigen-like family member P) (Granule membrane protein 140) (GMP-140) (Leukocyte-endothelial cell adhesion molecule 3) (LECAM3) (Platelet activation dependent granule-external membrane protein) (PADGEM) (CD antigen CD62P) p-selectin (CD62 antigen-like family member P) (Granule membrane protein 140) (Leukocyte-endothelial cell adhesion molecule 3) (Platelet activation dependent granule-external membrane protein) Selectin P isoform 3 Selectin P |
| Synonyms | GMRP hCG_38007 GRMP |
| Description | FUNCTION: Ca(2+)-dependent receptor for myeloid cells that binds to carbohydrates on neutrophils and monocytes. Mediates the interaction of activated endothelial cells or platelets with leukocytes. The ligand recognized is sialyl-Lewis X. Mediates rapid rolling of leukocyte rolling over vascular surfaces during the initial steps in inflammation through interaction with SELPLG. . |
| Accessions | Q6NUL9 ENST00000426706.6 ENST00000367786.6 ENST00000367788.6 ENST00000263686.11 P16109 ENST00000458599.6 F6VVT6 ENST00000367795.2 A0A0S2Z4F5 Q5R345 Q5R349 Q5R341 A0A0S2Z509 Q8N1E9 Q5R342 |
