I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| glutamatergic neuron | 6 studies | 35% ± 22% | |
| neuron | 5 studies | 29% ± 11% | |
| GABAergic neuron | 4 studies | 22% ± 4% | |
| smooth muscle cell | 3 studies | 16% ± 1% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| glutamatergic neuron | 6 studies | 35% ± 22% | |
| neuron | 5 studies | 29% ± 11% | |
| GABAergic neuron | 4 studies | 22% ± 4% | |
| smooth muscle cell | 3 studies | 16% ± 1% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| brain | 5 studies | 29% ± 16% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| breast | 100% | 1343.25 | 457 / 459 | 91% | 18.50 | 1019 / 1118 |
| brain | 84% | 2766.04 | 2232 / 2642 | 99% | 37.77 | 701 / 705 |
| prostate | 100% | 1507.60 | 244 / 245 | 84% | 11.84 | 423 / 502 |
| bladder | 100% | 1360.62 | 21 / 21 | 53% | 4.45 | 269 / 504 |
| lung | 94% | 643.62 | 543 / 578 | 55% | 3.87 | 636 / 1155 |
| intestine | 97% | 1205.69 | 933 / 966 | 50% | 3.68 | 265 / 527 |
| uterus | 99% | 7635.59 | 169 / 170 | 44% | 7.89 | 202 / 459 |
| ovary | 100% | 1704.66 | 180 / 180 | 42% | 3.78 | 179 / 430 |
| skin | 78% | 1180.24 | 1411 / 1809 | 61% | 9.55 | 287 / 472 |
| esophagus | 87% | 1177.80 | 1263 / 1445 | 46% | 3.49 | 85 / 183 |
| stomach | 57% | 341.97 | 205 / 359 | 56% | 4.06 | 161 / 286 |
| thymus | 92% | 518.83 | 601 / 653 | 16% | 1.11 | 97 / 605 |
| pancreas | 17% | 67.97 | 55 / 328 | 88% | 11.65 | 157 / 178 |
| kidney | 45% | 263.02 | 40 / 89 | 58% | 5.47 | 521 / 901 |
| adipose | 99% | 919.55 | 1195 / 1204 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 99% | 24.96 | 79 / 80 |
| spleen | 90% | 506.64 | 218 / 241 | 0% | 0 | 0 / 0 |
| heart | 72% | 400.28 | 623 / 861 | 0% | 0 | 0 / 0 |
| adrenal gland | 33% | 127.70 | 84 / 258 | 37% | 6.32 | 84 / 230 |
| blood vessel | 50% | 304.57 | 663 / 1335 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 33% | 2.38 | 15 / 45 |
| lymph node | 0% | 0 | 0 / 0 | 24% | 0.91 | 7 / 29 |
| liver | 4% | 12.16 | 8 / 226 | 6% | 0.54 | 26 / 406 |
| muscle | 5% | 20.93 | 41 / 803 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| peripheral blood | 0% | 0 | 0 / 929 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0007420 | Biological process | brain development |
| GO_0051897 | Biological process | positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction |
| GO_0008284 | Biological process | positive regulation of cell population proliferation |
| GO_0009880 | Biological process | embryonic pattern specification |
| GO_0009887 | Biological process | animal organ morphogenesis |
| GO_0001654 | Biological process | eye development |
| GO_0045944 | Biological process | positive regulation of transcription by RNA polymerase II |
| GO_2001234 | Biological process | negative regulation of apoptotic signaling pathway |
| GO_0000785 | Cellular component | chromatin |
| GO_0005634 | Cellular component | nucleus |
| GO_1990837 | Molecular function | sequence-specific double-stranded DNA binding |
| GO_0000978 | Molecular function | RNA polymerase II cis-regulatory region sequence-specific DNA binding |
| GO_0001228 | Molecular function | DNA-binding transcription activator activity, RNA polymerase II-specific |
| GO_0000981 | Molecular function | DNA-binding transcription factor activity, RNA polymerase II-specific |
| GO_0043565 | Molecular function | sequence-specific DNA binding |
| GO_0003682 | Molecular function | chromatin binding |
| Gene name | MEIS3 |
| Protein name | MEIS1-related protein 2 MEIS3 protein Meis homeobox 3 Homeobox protein Meis3 (Meis1-related protein 2) |
| Synonyms | MRG2 |
| Description | FUNCTION: Transcriptional regulator which directly modulates PDPK1 expression, thus promoting survival of pancreatic beta-cells. Also regulates expression of NDFIP1, BNIP3, and CCNG1. . |
| Accessions | H0YMV2 Q49A38 U3KQV2 H0YNA8 ENST00000559338.1 ENST00000607695.1 ENST00000558555.6 [Q99687-1] ENST00000561096.5 ENST00000561293.5 [Q99687-2] Q99687 ENST00000557833.1 ENST00000441740.6 [Q99687-3] H3BLU4 H0YLL0 ENST00000331559.9 Q8TCW1 ENST00000559524.5 [Q99687-2] U3KQJ9 ENST00000560245.5 |
