OSBPL8 report

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I. Expression across cell types

Cell ontologyData table

Name	Number of supported studies	Average coverage
fibroblast	36 studies	32% ± 13%	Explore
macrophage	34 studies	30% ± 14%	Explore
natural killer cell	29 studies	27% ± 7%	Explore
CD4-positive, alpha-beta T cell	29 studies	27% ± 9%	Explore
B cell	28 studies	22% ± 6%	Explore
endothelial cell	27 studies	30% ± 13%	Explore
mast cell	26 studies	41% ± 14%	Explore
pericyte	25 studies	28% ± 10%	Explore
CD8-positive, alpha-beta T cell	25 studies	24% ± 7%	Explore
T cell	24 studies	26% ± 9%	Explore
conventional dendritic cell	24 studies	32% ± 13%	Explore
classical monocyte	23 studies	32% ± 11%	Explore
regulatory T cell	22 studies	28% ± 8%	Explore
monocyte	19 studies	31% ± 13%	Explore
non-classical monocyte	19 studies	34% ± 12%	Explore
smooth muscle cell	18 studies	23% ± 6%	Explore
naive B cell	18 studies	24% ± 6%	Explore
memory B cell	17 studies	21% ± 5%	Explore
dendritic cell	16 studies	36% ± 16%	Explore
CD16-positive, CD56-dim natural killer cell, human	15 studies	27% ± 5%	Explore
plasmacytoid dendritic cell	15 studies	30% ± 9%	Explore
gamma-delta T cell	15 studies	28% ± 9%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	14 studies	28% ± 10%	Explore
CD16-negative, CD56-bright natural killer cell, human	14 studies	27% ± 7%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	13 studies	25% ± 8%	Explore
microglial cell	13 studies	37% ± 12%	Explore
mucosal invariant T cell	13 studies	25% ± 4%	Explore
myeloid cell	13 studies	34% ± 16%	Explore
CD8-positive, alpha-beta memory T cell	12 studies	27% ± 7%	Explore
glutamatergic neuron	12 studies	56% ± 24%	Explore
oligodendrocyte precursor cell	12 studies	31% ± 12%	Explore
mature NK T cell	12 studies	25% ± 6%	Explore
endothelial cell of lymphatic vessel	11 studies	26% ± 9%	Explore
CD4-positive, alpha-beta memory T cell	11 studies	27% ± 7%	Explore
GABAergic neuron	11 studies	54% ± 25%	Explore
astrocyte	11 studies	30% ± 15%	Explore
effector memory CD8-positive, alpha-beta T cell	11 studies	29% ± 7%	Explore
leukocyte	10 studies	33% ± 13%	Explore
oligodendrocyte	10 studies	30% ± 13%	Explore
basal cell	9 studies	27% ± 11%	Explore
neuron	9 studies	38% ± 15%	Explore
epithelial cell	9 studies	34% ± 13%	Explore
myofibroblast cell	9 studies	24% ± 8%	Explore
connective tissue cell	9 studies	27% ± 10%	Explore
type I pneumocyte	8 studies	21% ± 7%	Explore
adipocyte	8 studies	32% ± 8%	Explore
neutrophil	7 studies	26% ± 8%	Explore
mononuclear phagocyte	7 studies	28% ± 8%	Explore
capillary endothelial cell	7 studies	19% ± 3%	Explore
epithelial cell of proximal tubule	7 studies	22% ± 5%	Explore
retinal ganglion cell	7 studies	44% ± 17%	Explore
innate lymphoid cell	7 studies	23% ± 6%	Explore
retinal cone cell	7 studies	37% ± 15%	Explore
hematopoietic precursor cell	6 studies	30% ± 13%	Explore
effector CD8-positive, alpha-beta T cell	6 studies	26% ± 5%	Explore
interneuron	6 studies	61% ± 21%	Explore
lymphocyte	6 studies	38% ± 15%	Explore
club cell	6 studies	21% ± 5%	Explore
Mueller cell	6 studies	24% ± 4%	Explore
T follicular helper cell	6 studies	24% ± 4%	Explore
effector memory CD4-positive, alpha-beta T cell	6 studies	31% ± 6%	Explore
effector CD4-positive, alpha-beta T cell	5 studies	26% ± 4%	Explore
abnormal cell	5 studies	29% ± 13%	Explore
endothelial cell of artery	5 studies	17% ± 1%	Explore
precursor B cell	5 studies	30% ± 6%	Explore
ciliated cell	5 studies	26% ± 6%	Explore
amacrine cell	5 studies	33% ± 9%	Explore
retina horizontal cell	5 studies	34% ± 14%	Explore
cardiac muscle cell	5 studies	37% ± 14%	Explore
type II pneumocyte	5 studies	20% ± 5%	Explore
effector memory CD8-positive, alpha-beta T cell, terminally differentiated	5 studies	24% ± 5%	Explore
exhausted T cell	4 studies	24% ± 9%	Explore
granule cell	4 studies	34% ± 5%	Explore
hematopoietic stem cell	4 studies	30% ± 14%	Explore
immature B cell	4 studies	22% ± 3%	Explore
retinal bipolar neuron	4 studies	21% ± 4%	Explore
retinal pigment epithelial cell	4 studies	36% ± 13%	Explore
OFF-bipolar cell	4 studies	41% ± 10%	Explore
ON-bipolar cell	4 studies	26% ± 7%	Explore
endothelial cell of vascular tree	4 studies	27% ± 11%	Explore
granulocyte	4 studies	38% ± 19%	Explore
muscle cell	4 studies	38% ± 21%	Explore
alveolar macrophage	4 studies	35% ± 14%	Explore
goblet cell	4 studies	30% ± 20%	Explore
hepatic stellate cell	3 studies	30% ± 13%	Explore
glomerular endothelial cell	3 studies	16% ± 0%	Explore
GABAergic interneuron	3 studies	58% ± 6%	Explore
glial cell	3 studies	27% ± 5%	Explore
progenitor cell	3 studies	34% ± 3%	Explore
megakaryocyte	3 studies	30% ± 13%	Explore
pro-B cell	3 studies	22% ± 1%	Explore
squamous epithelial cell	3 studies	33% ± 21%	Explore
mesothelial cell	3 studies	19% ± 3%	Explore
GABAergic amacrine cell	3 studies	48% ± 6%	Explore
glycinergic amacrine cell	3 studies	31% ± 4%	Explore
rod bipolar cell	3 studies	23% ± 7%	Explore
respiratory goblet cell	3 studies	18% ± 3%	Explore
secretory cell	3 studies	21% ± 4%	Explore
intermediate monocyte	3 studies	43% ± 23%	Explore
CD4-positive helper T cell	3 studies	30% ± 12%	Explore
luminal hormone-sensing cell of mammary gland	3 studies	20% ± 4%	Explore
hepatocyte	3 studies	41% ± 20%	Explore
ependymal cell	3 studies	30% ± 11%	Explore
adventitial cell	3 studies	30% ± 9%	Explore
group 3 innate lymphoid cell	3 studies	35% ± 16%	Explore
keratinocyte	3 studies	21% ± 5%	Explore
T-helper 1 cell	3 studies	22% ± 4%	Explore
central memory CD4-positive, alpha-beta T cell	3 studies	25% ± 1%	Explore
central memory CD8-positive, alpha-beta T cell	3 studies	22% ± 2%	Explore
double negative thymocyte	3 studies	32% ± 9%	Explore

II. Expression across tissues

sc-RNAseq dataData table

Name	Number of supported studies	Average coverage
brain	18 studies	40% ± 22%	Explore
peripheral blood	16 studies	29% ± 9%	Explore
lung	13 studies	25% ± 9%	Explore
eye	8 studies	28% ± 12%	Explore
kidney	7 studies	21% ± 3%	Explore
liver	6 studies	28% ± 12%	Explore
bone marrow	4 studies	31% ± 12%	Explore
heart	4 studies	30% ± 8%	Explore
uterus	4 studies	23% ± 7%	Explore
lymph node	4 studies	20% ± 3%	Explore
adipose	4 studies	30% ± 5%	Explore
intestine	3 studies	21% ± 7%	Explore
breast	3 studies	20% ± 7%	Explore

Bulk RNAseq dataData table

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
esophagus	100%	2967.66	1445 / 1445	100%	36.46	183 / 183
lung	100%	4928.15	577 / 578	100%	28.86	1152 / 1155
brain	99%	2972.89	2627 / 2642	100%	33.21	705 / 705
breast	100%	4057.72	459 / 459	98%	38.90	1099 / 1118
thymus	100%	2587.69	652 / 653	98%	18.83	590 / 605
kidney	100%	2400.89	89 / 89	97%	29.80	874 / 901
ovary	100%	2334.74	180 / 180	97%	13.33	417 / 430
prostate	100%	2313.56	244 / 245	96%	20.72	480 / 502
uterus	100%	3395.84	170 / 170	95%	20.74	437 / 459
stomach	99%	1765.93	357 / 359	95%	23.78	273 / 286
intestine	100%	2415.90	962 / 966	95%	19.77	502 / 527
bladder	100%	2687.76	21 / 21	95%	19.06	478 / 504
adrenal gland	100%	2257.28	258 / 258	93%	17.75	215 / 230
pancreas	94%	1265.76	308 / 328	98%	22.42	174 / 178
skin	100%	5366.16	1809 / 1809	92%	30.15	432 / 472
liver	96%	1188.17	217 / 226	69%	8.19	281 / 406
blood vessel	100%	3690.67	1335 / 1335	0%	0	0 / 0
spleen	100%	2983.18	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	25.14	45 / 45
adipose	100%	4441.06	1203 / 1204	0%	0	0 / 0
lymph node	0%	0	0 / 0	97%	19.69	28 / 29
muscle	97%	2110.64	775 / 803	0%	0	0 / 0
peripheral blood	94%	4333.76	877 / 929	0%	0	0 / 0
heart	93%	1495.99	801 / 861	0%	0	0 / 0
eye	0%	0	0 / 0	79%	17.91	63 / 80
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1