AMH | OmnibusX

sc-RNAseq data

Insufficient scRNA-seq data for expression of AMH at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
brain	97%	330.64	2569 / 2642	89%	17.93	625 / 705
intestine	89%	98.61	863 / 966	42%	4.39	222 / 527
uterus	72%	62.98	122 / 170	57%	7.35	261 / 459
pancreas	85%	112.85	280 / 328	40%	2.91	71 / 178
esophagus	72%	56.31	1044 / 1445	52%	5.12	95 / 183
prostate	85%	84.22	208 / 245	28%	2.17	141 / 502
ovary	76%	126.12	137 / 180	33%	4.09	142 / 430
lung	74%	55.38	429 / 578	25%	2.09	286 / 1155
thymus	78%	56.15	512 / 653	18%	0.90	107 / 605
breast	58%	41.77	266 / 459	37%	2.52	411 / 1118
bladder	52%	31.29	11 / 21	42%	3.92	210 / 504
kidney	78%	66.28	69 / 89	16%	1.12	148 / 901
muscle	93%	129.06	743 / 803	0%	0	0 / 0
adrenal gland	26%	16.60	66 / 258	58%	5.82	134 / 230
stomach	38%	24.13	137 / 359	43%	3.65	122 / 286
skin	60%	34.94	1086 / 1809	20%	1.55	95 / 472
spleen	70%	44.37	168 / 241	0%	0	0 / 0
lymph node	0%	0	0 / 0	62%	3.50	18 / 29
adipose	44%	21.72	524 / 1204	0%	0	0 / 0
liver	31%	14.39	71 / 226	12%	1.08	49 / 406
tonsil	0%	0	0 / 0	40%	3.48	18 / 45
blood vessel	39%	20.13	525 / 1335	0%	0	0 / 0
heart	19%	9.28	163 / 861	0%	0	0 / 0
peripheral blood	6%	2.54	58 / 929	0%	0	0 / 0
eye	0%	0	0 / 0	4%	0.15	3 / 80
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0007506	Biological process	gonadal mesoderm development
GO_1990262	Biological process	anti-Mullerian hormone receptor signaling pathway
GO_0001546	Biological process	preantral ovarian follicle growth
GO_0007548	Biological process	sex differentiation
GO_0001655	Biological process	urogenital system development
GO_0001541	Biological process	ovarian follicle development
GO_0010628	Biological process	positive regulation of gene expression
GO_0014070	Biological process	response to organic cyclic compound
GO_0060391	Biological process	positive regulation of SMAD protein signal transduction
GO_0007267	Biological process	cell-cell signaling
GO_0001880	Biological process	Mullerian duct regression
GO_2000355	Biological process	negative regulation of ovarian follicle development
GO_0033327	Biological process	Leydig cell differentiation
GO_0009410	Biological process	response to xenobiotic stimulus
GO_0007530	Biological process	sex determination
GO_0005615	Cellular component	extracellular space
GO_0005576	Cellular component	extracellular region
GO_0005179	Molecular function	hormone activity
GO_0005102	Molecular function	signaling receptor binding
GO_0008083	Molecular function	growth factor activity
GO_0005114	Molecular function	type II transforming growth factor beta receptor binding
GO_0005515	Molecular function	protein binding

Gene name	AMH
Protein name	Muellerian-inhibiting factor (Anti-Muellerian hormone) (AMH) (Muellerian-inhibiting substance) (MIS) Muellerian-inhibiting factor (Anti-Muellerian hormone) (Muellerian-inhibiting substance) Muellerian-inhibiting factor
Synonyms	MIF
Description	FUNCTION: Plays an important role in several reproductive functions. Induces Muellerian duct regression during male fetal sexual differentiation . Also plays a role in Leydig cell differentiation and function (By similarity). In female acts as a negative regulator of the primordial to primary follicle transition and decreases FSH sensitivity of growing follicles . AMH signals by binding to a specific type-II receptor, AMHR2, that heterodimerizes with type-I receptors (ACVR1 and BMPR1A), and recruiting SMAD proteins that are translocated to the nucleus to regulate target gene expression . .
Accessions	ENST00000221496.5 A0A348FVH7 P03971 A0A348FVH8

AMH report