Interactors | Protein name | Directionality | Classification | |
|---|---|---|---|---|
| 1 | AMH-ACVR1+AMHR2 | MIS_HUMAN - | Ligand-Receptor | Signaling by Muellerian-inhibiting factor |
| 2 | AMH-AMHR2+BMPR1A | MIS_HUMAN - | Ligand-Receptor | Signaling by Muellerian-inhibiting factor |
| 3 | AMH-AMHR2+BMPR1B | MIS_HUMAN - | Ligand-Receptor | Signaling by Muellerian-inhibiting factor |
| Name | anti-Mullerian hormone receptor signaling pathway |
| ID | GO_1990262 |
| collection_id | Biological process |
| Exact synonym | anti-Mullerian hormone signaling pathway |
| Description | The series of molecular signals initiated by the binding of anti-Mullerian hormone to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription. Upon ligand binding, the receptor forms a complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. |
| Comment | An example of this is Amhr2 in M. musculus (Q8K592) a receptor for anti-mullerian hormone, described in PMID:23624077. |
| External URL | |
| Genes |