AMHR2 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of AMHR2 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of AMHR2 at tissue level.

III. Associated gene sets

GO_1990262Biological processanti-Mullerian hormone receptor signaling pathway
GO_0007548Biological processsex differentiation
GO_0071363Biological processcellular response to growth factor stimulus
GO_0030509Biological processBMP signaling pathway
GO_0001880Biological processMullerian duct regression
GO_0001568Biological processblood vessel development
GO_0008584Biological processmale gonad development
GO_0006468Biological processprotein phosphorylation
GO_0008585Biological processfemale gonad development
GO_0007179Biological processtransforming growth factor beta receptor signaling pathway
GO_0043235Cellular componentreceptor complex
GO_0005886Cellular componentplasma membrane
GO_0042803Molecular functionprotein homodimerization activity
GO_1990272Molecular functionanti-Mullerian hormone receptor activity
GO_0042562Molecular functionhormone binding
GO_0005024Molecular functiontransforming growth factor beta receptor activity
GO_0046872Molecular functionmetal ion binding
GO_0005524Molecular functionATP binding
GO_0005026Molecular functiontransforming growth factor beta receptor activity, type II
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameAMHR2
Protein nameAnti-Muellerian hormone type-2 receptor (EC 2.7.11.30) (Anti-Muellerian hormone type II receptor) (AMH type II receptor) (MIS type II receptor) (MISRII) (MRII)
receptor protein serine/threonine kinase (EC 2.7.11.30)
SynonymsMISR2
AMHR
DescriptionFUNCTION: On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for anti-Muellerian hormone.

AccessionsENST00000379791.7 [Q16671-3]
ENST00000257863.9 [Q16671-1]
H3BPI9
ENST00000550839.1
ENST00000550311.5 [Q16671-2]
Q16671