Insufficient scRNA-seq data for expression of AMHR2 at single-cell level.
Insufficient scRNA-seq data for expression of AMHR2 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
adrenal gland | 100% | 3057.24 | 258 / 258 | 47% | 28.83 | 109 / 230 |
ovary | 99% | 1956.36 | 179 / 180 | 30% | 1.27 | 127 / 430 |
pancreas | 100% | 295.31 | 328 / 328 | 13% | 0.26 | 24 / 178 |
spleen | 100% | 485.77 | 241 / 241 | 0% | 0 | 0 / 0 |
muscle | 98% | 100.65 | 785 / 803 | 0% | 0 | 0 / 0 |
stomach | 60% | 26.85 | 215 / 359 | 4% | 0.50 | 11 / 286 |
liver | 47% | 16.87 | 107 / 226 | 1% | 0.06 | 5 / 406 |
lung | 42% | 12.25 | 240 / 578 | 4% | 0.13 | 41 / 1155 |
prostate | 36% | 10.02 | 87 / 245 | 6% | 0.07 | 29 / 502 |
adipose | 39% | 23.93 | 465 / 1204 | 0% | 0 | 0 / 0 |
bladder | 33% | 10.57 | 7 / 21 | 1% | 0.01 | 3 / 504 |
heart | 33% | 10.35 | 280 / 861 | 0% | 0 | 0 / 0 |
esophagus | 30% | 9.95 | 434 / 1445 | 2% | 0.10 | 4 / 183 |
skin | 20% | 5.48 | 363 / 1809 | 7% | 0.45 | 34 / 472 |
uterus | 23% | 8.15 | 39 / 170 | 3% | 0.36 | 15 / 459 |
intestine | 17% | 4.65 | 167 / 966 | 2% | 0.09 | 11 / 527 |
breast | 8% | 1.97 | 39 / 459 | 1% | 0.04 | 14 / 1118 |
kidney | 6% | 1.00 | 5 / 89 | 0% | 0.01 | 3 / 901 |
thymus | 3% | 0.74 | 19 / 653 | 1% | 0.03 | 6 / 605 |
blood vessel | 3% | 0.94 | 40 / 1335 | 0% | 0 | 0 / 0 |
brain | 3% | 1.36 | 71 / 2642 | 0% | 0 | 0 / 705 |
peripheral blood | 2% | 0.57 | 21 / 929 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 2% | 0.03 | 1 / 45 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_1990262 | Biological process | anti-Mullerian hormone receptor signaling pathway |
GO_0007548 | Biological process | sex differentiation |
GO_0071363 | Biological process | cellular response to growth factor stimulus |
GO_0030509 | Biological process | BMP signaling pathway |
GO_0001880 | Biological process | Mullerian duct regression |
GO_0001568 | Biological process | blood vessel development |
GO_0008584 | Biological process | male gonad development |
GO_0006468 | Biological process | protein phosphorylation |
GO_0008585 | Biological process | female gonad development |
GO_0007179 | Biological process | transforming growth factor beta receptor signaling pathway |
GO_0043235 | Cellular component | receptor complex |
GO_0005886 | Cellular component | plasma membrane |
GO_0042803 | Molecular function | protein homodimerization activity |
GO_1990272 | Molecular function | anti-Mullerian hormone receptor activity |
GO_0042562 | Molecular function | hormone binding |
GO_0005024 | Molecular function | transforming growth factor beta receptor activity |
GO_0046872 | Molecular function | metal ion binding |
GO_0005524 | Molecular function | ATP binding |
GO_0005026 | Molecular function | transforming growth factor beta receptor activity, type II |
GO_0005515 | Molecular function | protein binding |
Gene name | AMHR2 |
Protein name | Anti-Muellerian hormone type-2 receptor (EC 2.7.11.30) (Anti-Muellerian hormone type II receptor) (AMH type II receptor) (MIS type II receptor) (MISRII) (MRII) receptor protein serine/threonine kinase (EC 2.7.11.30) |
Synonyms | MISR2 AMHR |
Description | FUNCTION: On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for anti-Muellerian hormone. |
Accessions | ENST00000379791.7 [Q16671-3] ENST00000257863.9 [Q16671-1] H3BPI9 ENST00000550839.1 ENST00000550311.5 [Q16671-2] Q16671 |