transforming growth factor beta receptor activity

I. Literature review

[source]
Nametransforming growth factor beta receptor activity
IDGO_0005024
collection_id

Molecular function

Exact synonym

TGF-beta receptor activity, TGFbeta receptor activity, TGFbeta-activated receptor activity, TGFbetaR, transforming growth factor beta-activated receptor activity

Description

Combining with a transforming growth factor beta (TGFbeta) and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity by catalysis of the reaction: ATP protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate.

Comment

Note that this term represents an activity and not a gene product, and should only be used when the receptor binds the ligand TGFbeta. For binding to other growth factors, consider annotating to terms under 'transmembrane signaling receptor activity ; GO:0004888.

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Genes