Name | Number of supported studies | Average coverage | |
---|---|---|---|
fibroblast | 44 studies | 48% ± 20% | |
smooth muscle cell | 16 studies | 28% ± 12% | |
endothelial cell of lymphatic vessel | 14 studies | 23% ± 9% | |
connective tissue cell | 14 studies | 49% ± 18% | |
myofibroblast cell | 12 studies | 45% ± 19% | |
basal cell | 11 studies | 23% ± 8% | |
pericyte | 10 studies | 35% ± 13% | |
endothelial cell of artery | 9 studies | 36% ± 11% | |
mesothelial cell | 8 studies | 36% ± 19% | |
endothelial cell | 8 studies | 22% ± 6% | |
epithelial cell | 6 studies | 31% ± 15% | |
type I pneumocyte | 6 studies | 24% ± 7% | |
adventitial cell | 4 studies | 55% ± 20% | |
goblet cell | 4 studies | 25% ± 7% | |
progenitor cell | 3 studies | 26% ± 7% | |
glial cell | 3 studies | 31% ± 2% | |
glutamatergic neuron | 3 studies | 42% ± 6% | |
Schwann cell | 3 studies | 39% ± 20% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
prostate | 100% | 51237.81 | 245 / 245 | 99% | 104.90 | 498 / 502 |
esophagus | 98% | 36324.52 | 1414 / 1445 | 99% | 90.36 | 181 / 183 |
intestine | 99% | 27185.86 | 959 / 966 | 96% | 61.05 | 507 / 527 |
thymus | 99% | 35991.72 | 646 / 653 | 95% | 123.23 | 576 / 605 |
uterus | 100% | 64902.94 | 170 / 170 | 92% | 59.49 | 422 / 459 |
lung | 99% | 45662.99 | 575 / 578 | 92% | 53.92 | 1064 / 1155 |
ovary | 100% | 56526.52 | 180 / 180 | 90% | 79.02 | 389 / 430 |
stomach | 89% | 17934.07 | 318 / 359 | 95% | 68.97 | 272 / 286 |
bladder | 100% | 36572.90 | 21 / 21 | 82% | 34.66 | 414 / 504 |
breast | 93% | 20034.26 | 429 / 459 | 73% | 20.41 | 816 / 1118 |
skin | 71% | 10272.57 | 1280 / 1809 | 92% | 38.86 | 433 / 472 |
adrenal gland | 48% | 5008.74 | 124 / 258 | 84% | 42.55 | 194 / 230 |
kidney | 64% | 9055.13 | 57 / 89 | 62% | 22.01 | 558 / 901 |
pancreas | 8% | 689.70 | 25 / 328 | 96% | 63.99 | 171 / 178 |
tonsil | 0% | 0 | 0 / 0 | 100% | 50.18 | 45 / 45 |
ureter | 0% | 0 | 0 / 0 | 100% | 29.39 | 1 / 1 |
blood vessel | 100% | 66957.84 | 1334 / 1335 | 0% | 0 | 0 / 0 |
heart | 97% | 35035.11 | 838 / 861 | 0% | 0 | 0 / 0 |
adipose | 97% | 26281.20 | 1166 / 1204 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 94% | 40.42 | 75 / 80 |
spleen | 92% | 14499.75 | 222 / 241 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 86% | 19.86 | 25 / 29 |
brain | 1% | 112.27 | 29 / 2642 | 85% | 41.13 | 600 / 705 |
liver | 11% | 998.36 | 24 / 226 | 41% | 13.49 | 167 / 406 |
muscle | 29% | 3164.55 | 231 / 803 | 0% | 0 | 0 / 0 |
peripheral blood | 2% | 174.65 | 16 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0017015 | Biological process | regulation of transforming growth factor beta receptor signaling pathway |
GO_0006457 | Biological process | protein folding |
GO_0007179 | Biological process | transforming growth factor beta receptor signaling pathway |
GO_0046879 | Biological process | hormone secretion |
GO_0001558 | Biological process | regulation of cell growth |
GO_0005615 | Cellular component | extracellular space |
GO_0001527 | Cellular component | microfibril |
GO_0005576 | Cellular component | extracellular region |
GO_0062023 | Cellular component | collagen-containing extracellular matrix |
GO_0031012 | Cellular component | extracellular matrix |
GO_0005201 | Molecular function | extracellular matrix structural constituent |
GO_0050431 | Molecular function | transforming growth factor beta binding |
GO_0005509 | Molecular function | calcium ion binding |
GO_0005515 | Molecular function | protein binding |
GO_0005539 | Molecular function | glycosaminoglycan binding |
GO_0005024 | Molecular function | transforming growth factor beta receptor activity |
GO_0005178 | Molecular function | integrin binding |
Gene name | LTBP4 |
Protein name | Latent-transforming growth factor beta-binding protein 4 (LTBP-4) Latent transforming growth factor beta binding protein 4 |
Synonyms | |
Description | FUNCTION: Key regulator of transforming growth factor beta (TGFB1, TGFB2 and TGFB3) that controls TGF-beta activation by maintaining it in a latent state during storage in extracellular space. Associates specifically via disulfide bonds with the Latency-associated peptide (LAP), which is the regulatory chain of TGF-beta, and regulates integrin-dependent activation of TGF-beta. . |
Accessions | M0QXV3 ENST00000599724.5 M0QYE9 A0A087WVV5 ENST00000622457.1 M0QZX0 ENST00000597071.5 A0A087WXC2 A0A087WYX7 ENST00000593463.5 ENST00000601032.5 ENST00000396819.8 [Q8N2S1-2] Q8N2S1 A0A087WUU1 ENST00000594537.2 ENST00000598166.2 M0R351 ENST00000612121.4 ENST00000308370.11 [Q8N2S1-1] A0A087X0A7 ENST00000243562.13 ENST00000599016.5 ENST00000618486.4 ENST00000599225.1 F8WAA0 A0A087WWZ7 ENST00000204005.13 A0A087WVR1 A0A0C4DH07 ENST00000600026.5 A0A087WXJ2 |