sex differentiation

I. Involved cell types

Genes
Cell types
No. of supported studies
Group 1
DMRT2PBX1
ionocyte
5 studies
Group 2
CNTFR
astrocyteconnective tissue cellinterstitial cell of Cajalmacroglial cellneuron
13 studies
Group 3
HNF4A
hepatocyteenterocyteepithelial cell
8 studies
Group 4
CDKL2CNOT9
GABAergic neurondopaminergic neuronglutamatergic neuron
8 studies

II. Involved cell-cell interactions

[source]
Interactors
Protein name
Directionality
Classification
1AMH-ACVR1+AMHR2MIS_HUMAN - Ligand-ReceptorSignaling by Muellerian-inhibiting factor
2AMH-AMHR2+BMPR1AMIS_HUMAN - Ligand-ReceptorSignaling by Muellerian-inhibiting factor
3AMH-AMHR2+BMPR1BMIS_HUMAN - Ligand-ReceptorSignaling by Muellerian-inhibiting factor

III. Literature review

[source]
Namesex differentiation
IDGO_0007548
collection_id

Biological process

Description

The establishment of the sex of an organism by physical differentiation.

External URL
Genes
CYP17A1AMHDMRT2DMRT3CNOT9DMRT1DMRTA1DMRTA2CNTFRHNF4ACENPITSPY1AMHR2PBX1CDKL2DMRTC2WNT7ASRYDMRTB1