DMRT3 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of DMRT3 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of DMRT3 at tissue level.

III. Associated gene sets

GO_0046661Biological processmale sex differentiation
GO_0007628Biological processadult walking behavior
GO_0019226Biological processtransmission of nerve impulse
GO_0007548Biological processsex differentiation
GO_0042487Biological processregulation of odontogenesis of dentin-containing tooth
GO_0021521Biological processventral spinal cord interneuron specification
GO_0006357Biological processregulation of transcription by RNA polymerase II
GO_0000785Cellular componentchromatin
GO_0005634Cellular componentnucleus
GO_1990837Molecular functionsequence-specific double-stranded DNA binding
GO_0000978Molecular functionRNA polymerase II cis-regulatory region sequence-specific DNA binding
GO_0005515Molecular functionprotein binding
GO_0000981Molecular functionDNA-binding transcription factor activity, RNA polymerase II-specific
GO_0046872Molecular functionmetal ion binding

IV. Literature review

[source]
Gene nameDMRT3
Protein nameDoublesex- and mab-3-related transcription factor 3
Doublesex and mab-3 related transcription factor 3
SynonymsDMRTA3
DescriptionFUNCTION: Probable transcription factor that plays a role in configuring the spinal circuits controlling stride in vertebrates. Involved in neuronal specification within specific subdivision of spinal cord neurons and in the development of a coordinated locomotor network controlling limb movements. May regulate transcription during sexual development (By similarity). .

AccessionsENST00000417254.1
ENST00000190165.3
Q5W0Z5
Q9NQL9