DMRT2 | OmnibusX

Name	Number of supported studies	Average coverage
renal alpha-intercalated cell	7 studies	55% ± 9%	Explore
ionocyte	5 studies	43% ± 15%	Explore

sc-RNAseq data

Insufficient scRNA-seq data for expression of DMRT2 at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
lung	94%	238.52	545 / 578	42%	7.36	486 / 1155
breast	100%	463.42	458 / 459	24%	0.56	268 / 1118
brain	77%	93.45	2043 / 2642	42%	1.63	295 / 705
kidney	100%	3246.12	89 / 89	13%	20.96	117 / 901
muscle	97%	133.37	780 / 803	0%	0	0 / 0
skin	61%	34.79	1101 / 1809	33%	1.68	154 / 472
adipose	92%	288.17	1111 / 1204	0%	0	0 / 0
intestine	40%	56.04	382 / 966	44%	2.23	232 / 527
esophagus	33%	18.07	477 / 1445	37%	4.42	68 / 183
uterus	21%	11.42	35 / 170	44%	3.58	203 / 459
bladder	14%	4.76	3 / 21	33%	2.04	167 / 504
tonsil	0%	0	0 / 0	42%	3.21	19 / 45
eye	0%	0	0 / 0	36%	1.55	29 / 80
stomach	6%	2.22	21 / 359	26%	1.41	73 / 286
prostate	30%	23.02	73 / 245	1%	0.02	4 / 502
thymus	4%	13.79	25 / 653	15%	10.23	88 / 605
lymph node	0%	0	0 / 0	14%	0.57	4 / 29
adrenal gland	2%	0.92	6 / 258	10%	0.39	23 / 230
ovary	1%	0.33	2 / 180	9%	0.41	37 / 430
blood vessel	8%	5.45	113 / 1335	0%	0	0 / 0
heart	6%	2.63	52 / 861	0%	0	0 / 0
pancreas	1%	0.31	3 / 328	3%	0.09	6 / 178
liver	0%	0	0 / 226	3%	0.12	13 / 406
peripheral blood	1%	0.32	6 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
spleen	0%	0	0 / 241	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_2000287	Biological process	positive regulation of myotome development
GO_0048706	Biological process	embryonic skeletal system development
GO_0061055	Biological process	myotome development
GO_0007548	Biological process	sex differentiation
GO_0014807	Biological process	regulation of somitogenesis
GO_0008150	Biological process	biological_process
GO_0045944	Biological process	positive regulation of transcription by RNA polymerase II
GO_0006357	Biological process	regulation of transcription by RNA polymerase II
GO_0005575	Cellular component	cellular_component
GO_0000785	Cellular component	chromatin
GO_0005634	Cellular component	nucleus
GO_0000978	Molecular function	RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO_0000981	Molecular function	DNA-binding transcription factor activity, RNA polymerase II-specific
GO_0001228	Molecular function	DNA-binding transcription activator activity, RNA polymerase II-specific
GO_0005515	Molecular function	protein binding
GO_0042802	Molecular function	identical protein binding
GO_0046872	Molecular function	metal ion binding
GO_0003674	Molecular function	molecular_function

Gene name	DMRT2
Protein name	Doublesex- and mab-3-related transcription factor 2 (Doublesex-like 2 protein) (DSXL-2) Doublesex and mab-3 related transcription factor 2 DMRT2 protein (cDNA FLJ77088, highly similar to Homo sapiens doublesex and mab-3 related transcription factor 2 (DMRT2), transcript variant 1, mRNA)
Synonyms	DSXL2
Description	FUNCTION: Transcriptional activator that directly regulates early activation of the myogenic determination gene MYF5 by binding in a sequence-specific manner to the early epaxial enhancer element of it. Involved in somitogenesis during embryogenesis and somite development and differentiation into sclerotome and dermomyotome. Required for the initiation and/or maintenance of proper organization of the sclerotome, dermomyotome and myotome (By similarity). .
Accessions	ENST00000302441.7 ENST00000358146.7 [Q9Y5R5-1] Q9Y5R5 ENST00000412350.6 [Q9Y5R5-2] A0A0A0MR18 ENST00000635183.1 [Q9Y5R5-2] ENST00000382251.7 [Q9Y5R5-1] Q05C20 ENST00000259622.10 [Q9Y5R5-2] ENST00000382255.7 [Q9Y5R5-2]

DMRT2 report