SRPX2 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0090050Biological processpositive regulation of cell migration involved in sprouting angiogenesis
GO_0071625Biological processvocalization behavior
GO_0048870Biological processcell motility
GO_0001525Biological processangiogenesis
GO_0042325Biological processregulation of phosphorylation
GO_0098609Biological processcell-cell adhesion
GO_0051965Biological processpositive regulation of synapse assembly
GO_0005615Cellular componentextracellular space
GO_0009986Cellular componentcell surface
GO_0097060Cellular componentsynaptic membrane
GO_0060076Cellular componentexcitatory synapse
GO_0062023Cellular componentcollagen-containing extracellular matrix
GO_0005737Cellular componentcytoplasm
GO_0005201Molecular functionextracellular matrix structural constituent
GO_0036458Molecular functionhepatocyte growth factor binding
GO_0042802Molecular functionidentical protein binding
GO_0005102Molecular functionsignaling receptor binding
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameSRPX2
Protein nameSushi repeat containing protein X-linked 2
Sushi repeat-containing protein SRPX2
Sushi repeat-containing protein SRPX2 (Sushi-repeat protein upregulated in leukemia)
SynonymsSRPUL
DescriptionFUNCTION: Acts as a ligand for the urokinase plasminogen activator surface receptor. Plays a role in angiogenesis by inducing endothelial cell migration and the formation of vascular network (cords). Involved in cellular migration and adhesion. Increases the phosphorylation levels of FAK. Interacts with and increases the mitogenic activity of HGF. Promotes synapse formation. May have a role in the perisylvian region, critical for language and cognitive development. .

AccessionsA0A1W2PRB1
ENST00000640282.1
A0A1W2PR88
O60687
ENST00000638458.1
ENST00000640889.1
A0A1W2PNZ6
ENST00000373004.5