Name | Number of supported studies | Average coverage | |
---|---|---|---|
fibroblast | 6 studies | 22% ± 5% | |
connective tissue cell | 4 studies | 31% ± 19% | |
endothelial cell | 4 studies | 30% ± 8% | |
microglial cell | 4 studies | 19% ± 3% | |
glutamatergic neuron | 4 studies | 36% ± 15% | |
epithelial cell | 3 studies | 35% ± 16% | |
myeloid cell | 3 studies | 24% ± 4% | |
macrophage | 3 studies | 21% ± 0% | |
GABAergic neuron | 3 studies | 30% ± 10% | |
pericyte | 3 studies | 21% ± 1% | |
basal cell | 3 studies | 17% ± 1% | |
goblet cell | 3 studies | 17% ± 1% | |
neuron | 3 studies | 25% ± 9% |
Name | Number of supported studies | Average coverage | |
---|---|---|---|
brain | 5 studies | 25% ± 11% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
prostate | 100% | 4435.38 | 245 / 245 | 100% | 89.95 | 500 / 502 |
skin | 100% | 5035.64 | 1809 / 1809 | 100% | 129.25 | 470 / 472 |
breast | 100% | 4312.67 | 459 / 459 | 99% | 88.11 | 1109 / 1118 |
stomach | 100% | 2142.97 | 359 / 359 | 99% | 55.12 | 283 / 286 |
intestine | 100% | 2768.34 | 966 / 966 | 99% | 58.30 | 520 / 527 |
lung | 100% | 3159.94 | 576 / 578 | 99% | 71.52 | 1143 / 1155 |
ovary | 100% | 3384.48 | 180 / 180 | 99% | 61.96 | 424 / 430 |
uterus | 100% | 4074.62 | 170 / 170 | 98% | 73.32 | 450 / 459 |
bladder | 100% | 3809.33 | 21 / 21 | 98% | 65.53 | 494 / 504 |
pancreas | 99% | 1657.49 | 325 / 328 | 99% | 75.91 | 176 / 178 |
adrenal gland | 100% | 5458.47 | 258 / 258 | 97% | 59.09 | 224 / 230 |
kidney | 99% | 1798.29 | 88 / 89 | 97% | 45.80 | 873 / 901 |
esophagus | 98% | 2138.47 | 1412 / 1445 | 96% | 75.27 | 175 / 183 |
thymus | 100% | 2603.77 | 652 / 653 | 93% | 42.16 | 560 / 605 |
liver | 100% | 2430.46 | 226 / 226 | 90% | 35.85 | 367 / 406 |
brain | 81% | 884.29 | 2140 / 2642 | 96% | 50.97 | 676 / 705 |
adipose | 100% | 5048.78 | 1204 / 1204 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 100% | 53.34 | 80 / 80 |
tonsil | 0% | 0 | 0 / 0 | 100% | 59.04 | 45 / 45 |
ureter | 0% | 0 | 0 / 0 | 100% | 53.97 | 1 / 1 |
blood vessel | 100% | 4561.08 | 1334 / 1335 | 0% | 0 | 0 / 0 |
spleen | 97% | 1863.29 | 234 / 241 | 0% | 0 | 0 / 0 |
heart | 97% | 2764.94 | 832 / 861 | 0% | 0 | 0 / 0 |
muscle | 52% | 481.88 | 417 / 803 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 48% | 11.59 | 14 / 29 |
peripheral blood | 3% | 23.95 | 28 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0042102 | Biological process | positive regulation of T cell proliferation |
GO_0032729 | Biological process | positive regulation of type II interferon production |
GO_0050776 | Biological process | regulation of immune response |
GO_0050852 | Biological process | T cell receptor signaling pathway |
GO_0042110 | Biological process | T cell activation |
GO_0001817 | Biological process | regulation of cytokine production |
GO_0009897 | Cellular component | external side of plasma membrane |
GO_0016020 | Cellular component | membrane |
GO_0005102 | Molecular function | signaling receptor binding |
GO_0005515 | Molecular function | protein binding |
Gene name | CD276 |
Protein name | CD276 antigen (4Ig-B7-H3) (B7 homolog 3) (B7-H3) (Costimulatory molecule) (CD antigen CD276) CD276 molecule |
Synonyms | B7H3 PSEC0249 UNQ309/PRO352 |
Description | FUNCTION: May participate in the regulation of T-cell-mediated immune response. May play a protective role in tumor cells by inhibiting natural-killer mediated cell lysis as well as a role of marker for detection of neuroblastoma cells. May be involved in the development of acute and chronic transplant rejection and in the regulation of lymphocytic activity at mucosal surfaces. Could also play a key role in providing the placenta and fetus with a suitable immunological environment throughout pregnancy. Both isoform 1 and isoform 2 appear to be redundant in their ability to modulate CD4 T-cell responses. Isoform 2 is shown to enhance the induction of cytotoxic T-cells and selectively stimulates interferon gamma production in the presence of T-cell receptor signaling. . |
Accessions | ENST00000318424.9 [Q5ZPR3-2] ENST00000567189.5 H0YN85 ENST00000318443.10 [Q5ZPR3-1] H0YL10 ENST00000537340.6 ENST00000560995.5 H0YN29 H3BM68 ENST00000564751.5 [Q5ZPR3-2] ENST00000561213.5 [Q5ZPR3-4] ENST00000561260.5 H0YK59 Q5ZPR3 ENST00000563584.5 ENST00000561176.5 H0YLT3 ENST00000560928.5 H0YKQ9 ENST00000558689.5 A0A0C4DGH0 ENST00000561416.5 ENST00000559073.1 H0YK40 ENST00000567582.5 ENST00000560786.6 H0YLT8 |