Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| basal cell | 17 studies | 32% ± 17% | |
| fibroblast | 13 studies | 31% ± 11% | |
| epithelial cell | 8 studies | 29% ± 12% | |
| secretory cell | 8 studies | 47% ± 21% | |
| club cell | 6 studies | 42% ± 21% | |
| respiratory goblet cell | 6 studies | 40% ± 23% | |
| ciliated cell | 6 studies | 28% ± 13% | |
| macrophage | 4 studies | 34% ± 13% | |
| connective tissue cell | 4 studies | 31% ± 7% | |
| endothelial cell of vascular tree | 4 studies | 22% ± 3% | |
| neutrophil | 3 studies | 23% ± 1% | |
| classical monocyte | 3 studies | 27% ± 4% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| lung | 98% | 2118.88 | 566 / 578 | 73% | 121.87 | 843 / 1155 |
| intestine | 60% | 624.75 | 578 / 966 | 93% | 195.98 | 489 / 527 |
| pancreas | 74% | 624.32 | 242 / 328 | 67% | 48.91 | 120 / 178 |
| stomach | 46% | 343.83 | 165 / 359 | 89% | 210.21 | 255 / 286 |
| esophagus | 45% | 768.54 | 647 / 1445 | 85% | 207.48 | 155 / 183 |
| kidney | 91% | 869.13 | 81 / 89 | 34% | 29.20 | 308 / 901 |
| spleen | 100% | 9985.13 | 241 / 241 | 0% | 0 | 0 / 0 |
| prostate | 78% | 903.43 | 190 / 245 | 22% | 13.77 | 111 / 502 |
| uterus | 15% | 86.98 | 25 / 170 | 70% | 212.17 | 323 / 459 |
| bladder | 24% | 139.19 | 5 / 21 | 61% | 103.66 | 308 / 504 |
| tonsil | 0% | 0 | 0 / 0 | 76% | 141.58 | 34 / 45 |
| peripheral blood | 74% | 449.70 | 684 / 929 | 0% | 0 | 0 / 0 |
| liver | 41% | 152.27 | 92 / 226 | 27% | 33.31 | 108 / 406 |
| skin | 37% | 1459.47 | 672 / 1809 | 29% | 22.33 | 137 / 472 |
| heart | 61% | 694.29 | 529 / 861 | 0% | 0 | 0 / 0 |
| ovary | 14% | 82.90 | 26 / 180 | 40% | 31.67 | 174 / 430 |
| adipose | 46% | 796.65 | 553 / 1204 | 0% | 0 | 0 / 0 |
| breast | 39% | 171.98 | 178 / 459 | 7% | 4.08 | 73 / 1118 |
| brain | 28% | 122.15 | 752 / 2642 | 6% | 3.33 | 40 / 705 |
| adrenal gland | 25% | 213.03 | 64 / 258 | 3% | 4.22 | 6 / 230 |
| thymus | 21% | 72.02 | 137 / 653 | 6% | 4.61 | 36 / 605 |
| blood vessel | 22% | 122.18 | 293 / 1335 | 0% | 0 | 0 / 0 |
| muscle | 8% | 23.51 | 66 / 803 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 7% | 12.80 | 2 / 29 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0008285 | Biological process | negative regulation of cell population proliferation |
| GO_0006954 | Biological process | inflammatory response |
| GO_0007165 | Biological process | signal transduction |
| GO_0030593 | Biological process | neutrophil chemotaxis |
| GO_0006935 | Biological process | chemotaxis |
| GO_0030036 | Biological process | actin cytoskeleton organization |
| GO_0007186 | Biological process | G protein-coupled receptor signaling pathway |
| GO_0035556 | Biological process | intracellular signal transduction |
| GO_0070098 | Biological process | chemokine-mediated signaling pathway |
| GO_0071222 | Biological process | cellular response to lipopolysaccharide |
| GO_0061844 | Biological process | antimicrobial humoral immune response mediated by antimicrobial peptide |
| GO_0007399 | Biological process | nervous system development |
| GO_0005615 | Cellular component | extracellular space |
| GO_0005576 | Cellular component | extracellular region |
| GO_0035580 | Cellular component | specific granule lumen |
| GO_1904724 | Cellular component | tertiary granule lumen |
| GO_0008047 | Molecular function | enzyme activator activity |
| GO_0008009 | Molecular function | chemokine activity |
| GO_0005102 | Molecular function | signaling receptor binding |
| GO_0008083 | Molecular function | growth factor activity |
| GO_0045236 | Molecular function | CXCR chemokine receptor binding |
| GO_0005515 | Molecular function | protein binding |
| Gene name | CXCL1 |
| Protein name | Growth-regulated alpha protein (C-X-C motif chemokine 1) (GRO-alpha(1-73)) (Melanoma growth stimulatory activity) (MGSA) (Neutrophil-activating protein 3) (NAP-3) [Cleaved into: GRO-alpha(4-73); GRO-alpha(5-73); GRO-alpha(6-73)] |
| Synonyms | GRO GROA SCYB1 GRO1 MGSA |
| Description | FUNCTION: Has chemotactic activity for neutrophils. May play a role in inflammation and exerts its effects on endothelial cells in an autocrine fashion. In vitro, the processed forms GRO-alpha(4-73), GRO-alpha(5-73) and GRO-alpha(6-73) show a 30-fold higher chemotactic activity. . |
| Accessions | P09341 ENST00000395761.4 |