Insufficient scRNA-seq data for expression of SLC6A3 at single-cell level.
Insufficient scRNA-seq data for expression of SLC6A3 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
kidney | 74% | 40.18 | 66 / 89 | 55% | 82.47 | 496 / 901 |
lung | 95% | 81.42 | 549 / 578 | 27% | 4.07 | 307 / 1155 |
thymus | 99% | 201.61 | 649 / 653 | 16% | 1.30 | 95 / 605 |
ovary | 97% | 98.19 | 174 / 180 | 8% | 0.24 | 35 / 430 |
prostate | 81% | 39.69 | 199 / 245 | 16% | 0.43 | 78 / 502 |
uterus | 90% | 67.35 | 153 / 170 | 3% | 0.12 | 15 / 459 |
bladder | 76% | 66.67 | 16 / 21 | 4% | 0.22 | 19 / 504 |
adipose | 72% | 58.78 | 868 / 1204 | 0% | 0 | 0 / 0 |
breast | 67% | 29.70 | 308 / 459 | 3% | 0.11 | 32 / 1118 |
esophagus | 53% | 22.62 | 772 / 1445 | 5% | 0.36 | 10 / 183 |
blood vessel | 59% | 21.43 | 784 / 1335 | 0% | 0 | 0 / 0 |
stomach | 53% | 24.76 | 191 / 359 | 5% | 0.80 | 13 / 286 |
spleen | 58% | 16.14 | 139 / 241 | 0% | 0 | 0 / 0 |
intestine | 48% | 19.92 | 465 / 966 | 2% | 0.09 | 9 / 527 |
heart | 33% | 9.47 | 281 / 861 | 0% | 0 | 0 / 0 |
skin | 30% | 9.50 | 544 / 1809 | 1% | 0.03 | 3 / 472 |
brain | 18% | 817.73 | 485 / 2642 | 1% | 0.29 | 9 / 705 |
adrenal gland | 13% | 2.32 | 34 / 258 | 5% | 0.30 | 11 / 230 |
eye | 0% | 0 | 0 / 0 | 18% | 0.31 | 14 / 80 |
pancreas | 9% | 2.16 | 30 / 328 | 1% | 0.01 | 1 / 178 |
liver | 4% | 0.85 | 10 / 226 | 3% | 0.26 | 13 / 406 |
peripheral blood | 7% | 1.82 | 63 / 929 | 0% | 0 | 0 / 0 |
muscle | 5% | 1.16 | 44 / 803 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 45 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0010039 | Biological process | response to iron ion |
GO_0015844 | Biological process | monoamine transport |
GO_0021984 | Biological process | adenohypophysis development |
GO_0042053 | Biological process | regulation of dopamine metabolic process |
GO_0090494 | Biological process | dopamine uptake |
GO_0051583 | Biological process | dopamine uptake involved in synaptic transmission |
GO_0007608 | Biological process | sensory perception of smell |
GO_0045471 | Biological process | response to ethanol |
GO_0042416 | Biological process | dopamine biosynthetic process |
GO_0015872 | Biological process | dopamine transport |
GO_0051591 | Biological process | response to cAMP |
GO_0042220 | Biological process | response to cocaine |
GO_0051620 | Biological process | norepinephrine uptake |
GO_0035094 | Biological process | response to nicotine |
GO_0006836 | Biological process | neurotransmitter transport |
GO_0015874 | Biological process | norepinephrine transport |
GO_0050890 | Biological process | cognition |
GO_0006865 | Biological process | amino acid transport |
GO_0007595 | Biological process | lactation |
GO_0009410 | Biological process | response to xenobiotic stimulus |
GO_0060134 | Biological process | prepulse inhibition |
GO_0007626 | Biological process | locomotory behavior |
GO_0040018 | Biological process | positive regulation of multicellular organism growth |
GO_0035725 | Biological process | sodium ion transmembrane transport |
GO_1990384 | Biological process | hyaloid vascular plexus regression |
GO_0042420 | Biological process | dopamine catabolic process |
GO_0005886 | Cellular component | plasma membrane |
GO_0045121 | Cellular component | membrane raft |
GO_0016020 | Cellular component | membrane |
GO_0043679 | Cellular component | axon terminus |
GO_0043025 | Cellular component | neuronal cell body |
GO_0098691 | Cellular component | dopaminergic synapse |
GO_0043005 | Cellular component | neuron projection |
GO_0016600 | Cellular component | flotillin complex |
GO_0032809 | Cellular component | neuronal cell body membrane |
GO_0042734 | Cellular component | presynaptic membrane |
GO_0009986 | Cellular component | cell surface |
GO_0005737 | Cellular component | cytoplasm |
GO_0045211 | Cellular component | postsynaptic membrane |
GO_0030424 | Cellular component | axon |
GO_0051721 | Molecular function | protein phosphatase 2A binding |
GO_1901363 | Molecular function | heterocyclic compound binding |
GO_0044877 | Molecular function | protein-containing complex binding |
GO_0005326 | Molecular function | neurotransmitter transmembrane transporter activity |
GO_0005102 | Molecular function | signaling receptor binding |
GO_0005334 | Molecular function | norepinephrine:sodium symporter activity |
GO_0008504 | Molecular function | monoamine transmembrane transporter activity |
GO_0002020 | Molecular function | protease binding |
GO_0043176 | Molecular function | amine binding |
GO_0046872 | Molecular function | metal ion binding |
GO_0035240 | Molecular function | dopamine binding |
GO_0005330 | Molecular function | dopamine:sodium symporter activity |
GO_0005515 | Molecular function | protein binding |
Gene name | SLC6A3 |
Protein name | Sodium-dependent dopamine transporter (DA transporter) (DAT) (Solute carrier family 6 member 3) Dopamine transporter |
Synonyms | DAT1 |
Description | FUNCTION: Mediates sodium- and chloride-dependent transport of dopamine . Also mediates sodium- and chloride-dependent transport of norepinephrine (also known as noradrenaline) (By similarity). Regulator of light-dependent retinal hyaloid vessel regression, downstream of OPN5 signaling (By similarity). . |
Accessions | Q01959 ENST00000270349.12 ENST00000621716.2 Q9Y610 |