CD58 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0071356Biological processcellular response to tumor necrosis factor
GO_0034113Biological processheterotypic cell-cell adhesion
GO_0098609Biological processcell-cell adhesion
GO_0032757Biological processpositive regulation of interleukin-8 production
GO_0071346Biological processcellular response to type II interferon
GO_0009986Cellular componentcell surface
GO_0030667Cellular componentsecretory granule membrane
GO_0070062Cellular componentextracellular exosome
GO_0005886Cellular componentplasma membrane
GO_0016020Cellular componentmembrane
GO_0101003Cellular componentficolin-1-rich granule membrane
GO_0005102Molecular functionsignaling receptor binding
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameCD58
Protein nameCD58 antigen, (Lymphocyte function-associated antigen 3), isoform CRA_c (CD58 molecule)
CD58 molecule
CD58 protein
Lymphocyte function-associated antigen 3 (Ag3) (Surface glycoprotein LFA-3) (CD antigen CD58)
SynonymshCG_37075
LFA3
DescriptionFUNCTION: Ligand of the T-lymphocyte CD2 glycoprotein. This interaction is important in mediating thymocyte interactions with thymic epithelial cells, antigen-independent and -dependent interactions of T-lymphocytes with target cells and antigen-presenting cells and the T-lymphocyte rosetting with erythrocytes. In addition, the LFA-3/CD2 interaction may prime response by both the CD2+ and LFA-3+ cells.

AccessionsENST00000369489.10 [P19256-1]
B1AMW1
H0YDI1
ENST00000464088.5 [P19256-2]
P19256
ENST00000526981.1
Q9BRW0
ENST00000457047.6 [P19256-3]
ENST00000369487.3