REN | OmnibusX

sc-RNAseq data

Insufficient scRNA-seq data for expression of REN at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
kidney	100%	9499.66	89 / 89	67%	103.10	606 / 901
liver	98%	30.19	221 / 226	43%	3.19	175 / 406
ovary	100%	1095.64	180 / 180	38%	3.82	164 / 430
uterus	88%	865.61	149 / 170	44%	7.10	204 / 459
adrenal gland	93%	90.34	241 / 258	33%	11.91	75 / 230
bladder	81%	279.90	17 / 21	44%	5.83	222 / 504
ureter	0%	0	0 / 0	100%	2.73	1 / 1
thymus	23%	2.63	153 / 653	71%	3.71	429 / 605
prostate	84%	30.79	205 / 245	4%	0.20	21 / 502
lung	64%	22.46	370 / 578	22%	0.60	251 / 1155
intestine	33%	9.37	318 / 966	39%	3.99	204 / 527
breast	55%	9.86	254 / 459	13%	0.28	140 / 1118
skin	56%	10.94	1019 / 1809	9%	0.61	41 / 472
spleen	63%	9.90	152 / 241	0%	0	0 / 0
brain	44%	4.75	1154 / 2642	3%	0.09	23 / 705
pancreas	14%	1.29	46 / 328	30%	9.55	54 / 178
adipose	44%	30.99	533 / 1204	0%	0	0 / 0
stomach	13%	1.55	47 / 359	26%	1.73	74 / 286
heart	35%	43.51	299 / 861	0%	0	0 / 0
esophagus	29%	5.11	421 / 1445	5%	0.30	10 / 183
tonsil	0%	0	0 / 0	24%	0.72	11 / 45
blood vessel	22%	2.27	290 / 1335	0%	0	0 / 0
muscle	6%	0.67	52 / 803	0%	0	0 / 0
peripheral blood	3%	0.44	28 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
eye	0%	0	0 / 0	0%	0	0 / 80
gingiva	0%	0	0 / 0	0%	0	0 / 0
lymph node	0%	0	0 / 0	0%	0	0 / 29
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

GO_0042756	Biological process	drinking behavior
GO_0071466	Biological process	cellular response to xenobiotic stimulus
GO_0050435	Biological process	amyloid-beta metabolic process
GO_0008217	Biological process	regulation of blood pressure
GO_0035902	Biological process	response to immobilization stress
GO_0072051	Biological process	juxtaglomerular apparatus development
GO_0001822	Biological process	kidney development
GO_0001823	Biological process	mesonephros development
GO_0051591	Biological process	response to cAMP
GO_0002003	Biological process	angiotensin maturation
GO_0006508	Biological process	proteolysis
GO_0002018	Biological process	renin-angiotensin regulation of aldosterone production
GO_0009755	Biological process	hormone-mediated signaling pathway
GO_0008584	Biological process	male gonad development
GO_0043408	Biological process	regulation of MAPK cascade
GO_0048469	Biological process	cell maturation
GO_0070305	Biological process	response to cGMP
GO_0032496	Biological process	response to lipopolysaccharide
GO_0005615	Cellular component	extracellular space
GO_0005576	Cellular component	extracellular region
GO_0005886	Cellular component	plasma membrane
GO_0045177	Cellular component	apical part of cell
GO_0008233	Molecular function	peptidase activity
GO_0005159	Molecular function	insulin-like growth factor receptor binding
GO_0005102	Molecular function	signaling receptor binding
GO_0004190	Molecular function	aspartic-type endopeptidase activity
GO_0005515	Molecular function	protein binding

Gene name	REN
Protein name	Renin (EC 3.4.23.15) (Angiotensinogenase)
Synonyms
Description	FUNCTION: Renin is a highly specific endopeptidase, whose only known function is to generate angiotensin I from angiotensinogen in the plasma, initiating a cascade of reactions that produce an elevation of blood pressure and increased sodium retention by the kidney. . FUNCTION: Renin is a highly specific endopeptidase, whose only known function is to generate angiotensin I from angiotensinogen in the plasma, initiating a cascade of reactions that produce an elevation of blood pressure and increased sodium retention by the kidney. .
Accessions	P00797 A0A1B0GUZ2 ENST00000638118.1 ENST00000272190.9 [P00797-1]

REN report