HLA-H report

I. Expression across cell types

Insufficient scRNA-seq data for expression of HLA-H at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of HLA-H at tissue level.

III. Associated gene sets

GO_0002476Biological processantigen processing and presentation of endogenous peptide antigen via MHC class Ib
GO_0002486Biological processantigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent
GO_0001916Biological processpositive regulation of T cell mediated cytotoxicity
GO_0006955Biological processimmune response
GO_0005615Cellular componentextracellular space
GO_0009897Cellular componentexternal side of plasma membrane
GO_0005886Cellular componentplasma membrane
GO_0031901Cellular componentearly endosome membrane
GO_0035577Cellular componentazurophil granule membrane
GO_0055038Cellular componentrecycling endosome membrane
GO_0009986Cellular componentcell surface
GO_0000139Cellular componentGolgi membrane
GO_0098553Cellular componentlumenal side of endoplasmic reticulum membrane
GO_0030670Cellular componentphagocytic vesicle membrane
GO_0042612Cellular componentMHC class I protein complex
GO_0012507Cellular componentER to Golgi transport vesicle membrane
GO_0005102Molecular functionsignaling receptor binding
GO_0030881Molecular functionbeta-2-microglobulin binding
GO_0005515Molecular functionprotein binding
GO_0042605Molecular functionpeptide antigen binding

IV. Literature review

[source]
Gene nameHLA-H
Protein nameMHC class I antigen
Hereditary haemochromatosis protein
Putative HLA class I histocompatibility antigen, alpha chain H (HLA-12.4) (HLA-AR) (MHC class I antigen H)
SynonymsHLAH
DescriptionFUNCTION: Involved in the presentation of foreign antigens to the immune system.

AccessionsA0A890BWF2
Q9UM46
P01893