NPFF report

I. Expression across cell types

Insufficient scRNA-seq data for expression of NPFF at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of NPFF at tissue level.

III. Associated gene sets

GO_0007218Biological processneuropeptide signaling pathway
GO_0007268Biological processchemical synaptic transmission
GO_0060079Biological processexcitatory postsynaptic potential
GO_0043204Cellular componentperikaryon
GO_0005615Cellular componentextracellular space
GO_0043679Cellular componentaxon terminus
GO_0005576Cellular componentextracellular region
GO_0098794Cellular componentpostsynapse
GO_0030425Cellular componentdendrite
GO_0001664Molecular functionG protein-coupled receptor binding
GO_0005102Molecular functionsignaling receptor binding
GO_0005184Molecular functionneuropeptide hormone activity

IV. Literature review

[source]
Gene nameNPFF
Protein namePro-FMRFamide-related neuropeptide FF (FMRFamide-related peptides) [Cleaved into: Neuropeptide SF (NPSF); Neuropeptide FF (NPFF); Neuropeptide AF (NPAF)]
Synonyms
DescriptionFUNCTION: Morphine modulating peptides. Have wide-ranging physiologic effects, including the modulation of morphine-induced analgesia, elevation of arterial blood pressure, and increased somatostatin secretion from the pancreas. Neuropeptide FF potentiates and sensitizes ASIC1 and ASIC3 channels. .

AccessionsO15130
ENST00000267017.4 [O15130-1]