HJV | OmnibusX

sc-RNAseq data

Insufficient scRNA-seq data for expression of HJV at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
liver	100%	5775.77	226 / 226	91%	218.96	368 / 406
muscle	100%	18739.02	803 / 803	0%	0	0 / 0
heart	94%	2109.21	809 / 861	0%	0	0 / 0
prostate	6%	25.66	14 / 245	6%	0.42	29 / 502
tonsil	0%	0	0 / 0	9%	0.49	4 / 45
uterus	0%	0	0 / 170	6%	1.75	27 / 459
peripheral blood	4%	16.56	33 / 929	0%	0	0 / 0
kidney	0%	0	0 / 89	3%	0.35	28 / 901
breast	1%	8.37	6 / 459	1%	0.07	9 / 1118
esophagus	1%	4.52	11 / 1445	1%	0.02	2 / 183
lung	1%	4.68	3 / 578	1%	0.05	14 / 1155
blood vessel	1%	11.30	18 / 1335	0%	0	0 / 0
skin	0%	9.06	8 / 1809	1%	0.01	4 / 472
thymus	1%	4.52	5 / 653	0%	0.03	3 / 605
stomach	0%	0	0 / 359	1%	0.01	3 / 286
ovary	0%	0	0 / 180	1%	0.05	4 / 430
adipose	1%	2.59	10 / 1204	0%	0	0 / 0
pancreas	0%	0	0 / 328	1%	0.01	1 / 178
spleen	0%	9.06	1 / 241	0%	0	0 / 0
intestine	0%	0.43	2 / 966	0%	0.10	1 / 527
brain	0%	0.18	1 / 2642	0%	0	0 / 705
abdomen	0%	0	0 / 0	0%	0	0 / 0
adrenal gland	0%	0	0 / 258	0%	0	0 / 230
bladder	0%	0	0 / 21	0%	0	0 / 504
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
eye	0%	0	0 / 0	0%	0	0 / 80
gingiva	0%	0	0 / 0	0%	0	0 / 0
lymph node	0%	0	0 / 0	0%	0	0 / 29
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0006366	Biological process	transcription by RNA polymerase II
GO_0032924	Biological process	activin receptor signaling pathway
GO_0071773	Biological process	cellular response to BMP stimulus
GO_0016540	Biological process	protein autoprocessing
GO_0060586	Biological process	multicellular organismal-level iron ion homeostasis
GO_0030514	Biological process	negative regulation of BMP signaling pathway
GO_0000122	Biological process	negative regulation of transcription by RNA polymerase II
GO_0030509	Biological process	BMP signaling pathway
GO_0006879	Biological process	intracellular iron ion homeostasis
GO_0045944	Biological process	positive regulation of transcription by RNA polymerase II
GO_0005615	Cellular component	extracellular space
GO_0005886	Cellular component	plasma membrane
GO_0009986	Cellular component	cell surface
GO_0098797	Cellular component	plasma membrane protein complex
GO_0070724	Cellular component	BMP receptor complex
GO_1990712	Cellular component	HFE-transferrin receptor complex
GO_0098552	Cellular component	side of membrane
GO_0015026	Molecular function	coreceptor activity
GO_1990459	Molecular function	transferrin receptor binding
GO_0098821	Molecular function	BMP receptor activity
GO_0005102	Molecular function	signaling receptor binding
GO_0036122	Molecular function	BMP binding
GO_0005515	Molecular function	protein binding

Gene name	HJV
Protein name	Hemochromatosis type 2 (Juvenile) (cDNA, FLJ79501, highly similar to Hemojuvelin) Hemojuvelin BMP co-receptor Hemojuvelin (Hemochromatosis type 2 protein) (Hemojuvelin BMP coreceptor) (RGM domain family member C)
Synonyms	RGMC RP4-679C16.1-002 HFE2
Description	FUNCTION: Acts as a bone morphogenetic protein (BMP) coreceptor . Through enhancement of BMP signaling regulates hepcidin (HAMP) expression and regulates iron homeostasis . .
Accessions	ENST00000636675.1 [Q6ZVN8-3] A8K466 Q6ZVN8 A0A0U1RR55 ENST00000357836.5 [Q6ZVN8-2] ENST00000497365.5 [Q6ZVN8-3] ENST00000421822.2 ENST00000336751.11 [Q6ZVN8-1] ENST00000475797.1 [Q6ZVN8-3] ENST00000634927.1 F8W6J7

HJV report