Interactors | Protein name | Directionality | Classification | |
---|---|---|---|---|
1 | BMPR1B+BMPR2-BMPR1A | - BMR1A_HUMAN | Receptor-Receptor | Signaling by BMP |
2 | HFE-TFRC | HFE_HUMAN - TFR1_HUMAN | Ligand-Receptor | |
3 | TF-TFR2 | TRFE_HUMAN - TFR2_HUMAN | Ligand-Receptor | Signaling by Transferrin |
4 | TF-TFRC | TRFE_HUMAN - TFR1_HUMAN | Ligand-Receptor | Signaling by Transferrin |
Name | HFE-transferrin receptor complex |
ID | GO_1990712 |
collection_id | Cellular component |
Description | A protein complex containing at least HFE and a transferrin receptor (either TFR1/TFRC or TFR2), proposed to play a role in the sensing of transferrin-bound Fe (Fe2-Tf) on the plasma membrane to regulate hepcidin transcription. |
External URL | |
Genes |