Name | Number of supported studies | Average coverage | |
---|---|---|---|
oligodendrocyte | 16 studies | 76% ± 14% | |
astrocyte | 15 studies | 47% ± 28% | |
hepatocyte | 6 studies | 84% ± 18% | |
endothelial cell | 6 studies | 38% ± 23% | |
microglial cell | 6 studies | 42% ± 20% | |
Mueller cell | 6 studies | 89% ± 14% | |
GABAergic neuron | 5 studies | 27% ± 12% | |
duct epithelial cell | 4 studies | 21% ± 3% | |
glutamatergic neuron | 4 studies | 33% ± 22% | |
retinal rod cell | 4 studies | 23% ± 5% | |
adipocyte | 4 studies | 35% ± 27% | |
oligodendrocyte precursor cell | 4 studies | 32% ± 10% | |
cholangiocyte | 3 studies | 52% ± 26% | |
hepatic stellate cell | 3 studies | 60% ± 25% | |
macrophage | 3 studies | 35% ± 17% | |
amacrine cell | 3 studies | 28% ± 2% | |
retina horizontal cell | 3 studies | 27% ± 6% | |
ciliated cell | 3 studies | 23% ± 3% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
brain | 100% | 27366.59 | 2636 / 2642 | 97% | 41.82 | 682 / 705 |
liver | 100% | 196961.48 | 226 / 226 | 93% | 618.66 | 378 / 406 |
breast | 57% | 1786.27 | 262 / 459 | 19% | 2.42 | 214 / 1118 |
adipose | 52% | 1884.30 | 621 / 1204 | 0% | 0 | 0 / 0 |
prostate | 31% | 674.22 | 76 / 245 | 13% | 0.52 | 66 / 502 |
skin | 7% | 145.04 | 128 / 1809 | 35% | 8.85 | 166 / 472 |
esophagus | 23% | 529.69 | 339 / 1445 | 9% | 1.14 | 16 / 183 |
eye | 0% | 0 | 0 / 0 | 26% | 14.03 | 21 / 80 |
tonsil | 0% | 0 | 0 / 0 | 16% | 0.92 | 7 / 45 |
lung | 0% | 0 | 0 / 578 | 11% | 2.76 | 125 / 1155 |
uterus | 0% | 0 | 0 / 170 | 8% | 0.87 | 39 / 459 |
kidney | 0% | 0 | 0 / 89 | 8% | 2.14 | 71 / 901 |
stomach | 2% | 47.21 | 7 / 359 | 6% | 1.12 | 16 / 286 |
pancreas | 1% | 16.78 | 3 / 328 | 6% | 5.44 | 11 / 178 |
intestine | 2% | 32.25 | 24 / 966 | 3% | 0.82 | 17 / 527 |
blood vessel | 5% | 239.70 | 72 / 1335 | 0% | 0 | 0 / 0 |
bladder | 0% | 0 | 0 / 21 | 5% | 0.65 | 24 / 504 |
heart | 3% | 78.13 | 28 / 861 | 0% | 0 | 0 / 0 |
thymus | 2% | 36.41 | 11 / 653 | 1% | 0.08 | 9 / 605 |
ovary | 1% | 9.31 | 1 / 180 | 1% | 0.03 | 3 / 430 |
spleen | 0% | 297.74 | 1 / 241 | 0% | 0 | 0 / 0 |
adrenal gland | 0% | 5.47 | 1 / 258 | 0% | 0 | 0 / 230 |
peripheral blood | 0% | 13.66 | 3 / 929 | 0% | 0 | 0 / 0 |
muscle | 0% | 4.61 | 2 / 803 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0042327 | Biological process | positive regulation of phosphorylation |
GO_0030316 | Biological process | osteoclast differentiation |
GO_0034756 | Biological process | regulation of iron ion transport |
GO_0019731 | Biological process | antibacterial humoral response |
GO_2000147 | Biological process | positive regulation of cell motility |
GO_0006826 | Biological process | iron ion transport |
GO_0048260 | Biological process | positive regulation of receptor-mediated endocytosis |
GO_0070371 | Biological process | ERK1 and ERK2 cascade |
GO_0045893 | Biological process | positive regulation of DNA-templated transcription |
GO_0006879 | Biological process | intracellular iron ion homeostasis |
GO_0007015 | Biological process | actin filament organization |
GO_0071281 | Biological process | cellular response to iron ion |
GO_0045780 | Biological process | positive regulation of bone resorption |
GO_0031647 | Biological process | regulation of protein stability |
GO_0045178 | Cellular component | basal part of cell |
GO_0016324 | Cellular component | apical plasma membrane |
GO_0005615 | Cellular component | extracellular space |
GO_0005576 | Cellular component | extracellular region |
GO_0005886 | Cellular component | plasma membrane |
GO_0031410 | Cellular component | cytoplasmic vesicle |
GO_0030139 | Cellular component | endocytic vesicle |
GO_0048471 | Cellular component | perinuclear region of cytoplasm |
GO_0055037 | Cellular component | recycling endosome |
GO_0005769 | Cellular component | early endosome |
GO_0070062 | Cellular component | extracellular exosome |
GO_0030669 | Cellular component | clathrin-coated endocytic vesicle membrane |
GO_0009925 | Cellular component | basal plasma membrane |
GO_0034774 | Cellular component | secretory granule lumen |
GO_0072562 | Cellular component | blood microparticle |
GO_0009986 | Cellular component | cell surface |
GO_0005788 | Cellular component | endoplasmic reticulum lumen |
GO_0005770 | Cellular component | late endosome |
GO_1990712 | Cellular component | HFE-transferrin receptor complex |
GO_0010008 | Cellular component | endosome membrane |
GO_0005905 | Cellular component | clathrin-coated pit |
GO_0031982 | Cellular component | vesicle |
GO_1990459 | Molecular function | transferrin receptor binding |
GO_0034986 | Molecular function | iron chaperone activity |
GO_0008198 | Molecular function | ferrous iron binding |
GO_0008199 | Molecular function | ferric iron binding |
GO_0005515 | Molecular function | protein binding |
Gene name | TF |
Protein name | Transferrin Serotransferrin (Beta-1 metal-binding globulin) (Siderophilin) TF protein Serotransferrin (Transferrin) (Beta-1 metal-binding globulin) (Siderophilin) Transferrin, isoform CRA_c (cDNA FLJ54029, highly similar to Serotransferrin) |
Synonyms | PRO1400 hCG_2023558 |
Description | FUNCTION: Transferrins are iron binding transport proteins which can bind two Fe(3+) ions in association with the binding of an anion, usually bicarbonate. It is responsible for the transport of iron from sites of absorption and heme degradation to those of storage and utilization. Serum transferrin may also have a further role in stimulating cell proliferation.; FUNCTION: (Microbial infection) Serves as an iron source for Neisseria species, which capture the protein and extract its iron for their own use. .; FUNCTION: (Microbial infection) Serves as an iron source for parasite T.brucei (strain 427), which capture TF via its own transferrin receptor ESAG6:ESAG7 and extract its iron for its own use. . FUNCTION: Transferrins are iron binding transport proteins which can bind two Fe(3+) ions in association with the binding of an anion, usually bicarbonate. It is responsible for the transport of iron from sites of absorption and heme degradation to those of storage and utilization. Serum transferrin may also have a further role in stimulating cell proliferation. . |
Accessions | ENST00000482271.5 F8WEK9 H7C5E8 ENST00000414694.5 A0PJA6 C9JB55 C9JVG0 F8WC57 ENST00000494430.5 ENST00000461695.1 Q06AH7 B4DHZ6 ENST00000485977.1 F8WCI6 ENST00000466911.5 P02787 ENST00000402696.9 |