Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| astrocyte | 19 studies | 63% ± 19% | |
| ciliated cell | 7 studies | 29% ± 12% | |
| club cell | 6 studies | 33% ± 17% | |
| Mueller cell | 4 studies | 45% ± 18% | |
| respiratory goblet cell | 4 studies | 52% ± 19% | |
| type I pneumocyte | 4 studies | 21% ± 5% | |
| basal cell | 4 studies | 26% ± 14% | |
| mesothelial cell | 3 studies | 27% ± 1% | |
| glutamatergic neuron | 3 studies | 27% ± 11% | |
| ependymal cell | 3 studies | 58% ± 19% | |
| renal principal cell | 3 studies | 62% ± 23% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| prostate | 95% | 2692.35 | 232 / 245 | 99% | 83.66 | 499 / 502 |
| brain | 97% | 1403.26 | 2570 / 2642 | 93% | 23.84 | 657 / 705 |
| ovary | 98% | 1286.89 | 176 / 180 | 75% | 9.88 | 323 / 430 |
| adrenal gland | 53% | 227.44 | 137 / 258 | 67% | 20.16 | 153 / 230 |
| kidney | 94% | 637.94 | 84 / 89 | 14% | 6.93 | 123 / 901 |
| blood vessel | 95% | 863.53 | 1267 / 1335 | 0% | 0 | 0 / 0 |
| stomach | 89% | 501.47 | 319 / 359 | 3% | 0.28 | 10 / 286 |
| uterus | 51% | 259.57 | 87 / 170 | 29% | 4.82 | 134 / 459 |
| esophagus | 63% | 856.07 | 904 / 1445 | 15% | 1.25 | 27 / 183 |
| breast | 17% | 62.68 | 76 / 459 | 58% | 119.40 | 654 / 1118 |
| lung | 43% | 159.59 | 247 / 578 | 19% | 2.22 | 214 / 1155 |
| skin | 17% | 49.24 | 315 / 1809 | 29% | 4.12 | 138 / 472 |
| intestine | 41% | 158.88 | 399 / 966 | 5% | 0.48 | 24 / 527 |
| pancreas | 17% | 48.46 | 57 / 328 | 16% | 1.20 | 28 / 178 |
| thymus | 24% | 64.46 | 155 / 653 | 7% | 0.96 | 45 / 605 |
| adipose | 30% | 111.55 | 360 / 1204 | 0% | 0 | 0 / 0 |
| spleen | 25% | 76.53 | 61 / 241 | 0% | 0 | 0 / 0 |
| muscle | 20% | 66.83 | 157 / 803 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 14% | 1.21 | 11 / 80 |
| bladder | 0% | 0 | 0 / 21 | 7% | 0.77 | 36 / 504 |
| heart | 7% | 22.45 | 59 / 861 | 0% | 0 | 0 / 0 |
| liver | 4% | 8.92 | 8 / 226 | 2% | 0.28 | 9 / 406 |
| tonsil | 0% | 0 | 0 / 0 | 2% | 0.19 | 1 / 45 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| peripheral blood | 0% | 0 | 0 / 929 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0030166 | Biological process | proteoglycan biosynthetic process |
| GO_0006954 | Biological process | inflammatory response |
| GO_0071773 | Biological process | cellular response to BMP stimulus |
| GO_0001649 | Biological process | osteoblast differentiation |
| GO_0010628 | Biological process | positive regulation of gene expression |
| GO_0021953 | Biological process | central nervous system neuron differentiation |
| GO_0032332 | Biological process | positive regulation of chondrocyte differentiation |
| GO_1902043 | Biological process | positive regulation of extrinsic apoptotic signaling pathway via death domain receptors |
| GO_0060041 | Biological process | retina development in camera-type eye |
| GO_0042698 | Biological process | ovulation cycle |
| GO_0071363 | Biological process | cellular response to growth factor stimulus |
| GO_0045669 | Biological process | positive regulation of osteoblast differentiation |
| GO_0001654 | Biological process | eye development |
| GO_0002063 | Biological process | chondrocyte development |
| GO_0009953 | Biological process | dorsal/ventral pattern formation |
| GO_0060350 | Biological process | endochondral bone morphogenesis |
| GO_0030509 | Biological process | BMP signaling pathway |
| GO_0001550 | Biological process | ovarian cumulus expansion |
| GO_1902731 | Biological process | negative regulation of chondrocyte proliferation |
| GO_0006468 | Biological process | protein phosphorylation |
| GO_0001502 | Biological process | cartilage condensation |
| GO_0031290 | Biological process | retinal ganglion cell axon guidance |
| GO_0030501 | Biological process | positive regulation of bone mineralization |
| GO_0061036 | Biological process | positive regulation of cartilage development |
| GO_0045944 | Biological process | positive regulation of transcription by RNA polymerase II |
| GO_0043235 | Cellular component | receptor complex |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0043025 | Cellular component | neuronal cell body |
| GO_0030425 | Cellular component | dendrite |
| GO_1990712 | Cellular component | HFE-transferrin receptor complex |
| GO_0004888 | Molecular function | transmembrane signaling receptor activity |
| GO_0098821 | Molecular function | BMP receptor activity |
| GO_0046332 | Molecular function | SMAD binding |
| GO_0004674 | Molecular function | protein serine/threonine kinase activity |
| GO_0004675 | Molecular function | transmembrane receptor protein serine/threonine kinase activity |
| GO_0036122 | Molecular function | BMP binding |
| GO_0046872 | Molecular function | metal ion binding |
| GO_0005524 | Molecular function | ATP binding |
| GO_0005025 | Molecular function | transforming growth factor beta receptor activity, type I |
| GO_0005515 | Molecular function | protein binding |
| Gene name | BMPR1B |
| Protein name | Bone morphogenetic protein receptor type-1B (BMP type-1B receptor) (BMPR-1B) (EC 2.7.11.30) (CD antigen CDw293) Bone morphogenetic protein receptor type 1B |
| Synonyms | |
| Description | FUNCTION: On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for BMP7/OP-1 and GDF5. Positively regulates chondrocyte differentiation through GDF5 interaction. . |
| Accessions | ENST00000672698.1 [O00238-1] ENST00000509540.6 [O00238-1] ENST00000515059.6 [O00238-1] D6RGW8 ENST00000440890.7 [O00238-2] ENST00000512312.5 [O00238-1] ENST00000506363.5 ENST00000394931.1 [O00238-1] O00238 ENST00000264568.8 [O00238-1] |
