IGFBP2 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0007584Biological processresponse to nutrient
GO_0032355Biological processresponse to estradiol
GO_0042104Biological processpositive regulation of activated T cell proliferation
GO_0043627Biological processresponse to estrogen
GO_0032870Biological processcellular response to hormone stimulus
GO_0007565Biological processfemale pregnancy
GO_0090090Biological processnegative regulation of canonical Wnt signaling pathway
GO_0051384Biological processresponse to glucocorticoid
GO_0032526Biological processresponse to retinoic acid
GO_0009612Biological processresponse to mechanical stimulus
GO_0009410Biological processresponse to xenobiotic stimulus
GO_0043567Biological processregulation of insulin-like growth factor receptor signaling pathway
GO_0016324Cellular componentapical plasma membrane
GO_0005615Cellular componentextracellular space
GO_0005576Cellular componentextracellular region
GO_0070062Cellular componentextracellular exosome
GO_0005102Molecular functionsignaling receptor binding
GO_0031994Molecular functioninsulin-like growth factor I binding
GO_0031995Molecular functioninsulin-like growth factor II binding
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameIGFBP2
Protein nameInsulin like growth factor binding protein 2
Insulin-like growth factor-binding protein 2
Insulin-like growth factor-binding protein 2 (IBP-2) (IGF-binding protein 2) (IGFBP-2)
SynonymsIBP2
BP2
DescriptionFUNCTION: Inhibits IGF-mediated growth and developmental rates. IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. .

AccessionsENST00000434997.1
P18065
ENST00000436812.1
C9JMY1
ENST00000456764.1
C9JW52
ENST00000233809.9
H7C1H0