NPVF report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of NPVF at tissue level.

III. Associated gene sets

GO_0007218Biological processneuropeptide signaling pathway
GO_0032277Biological processnegative regulation of gonadotropin secretion
GO_0005576Cellular componentextracellular region
GO_0005102Molecular functionsignaling receptor binding
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameNPVF
Protein namePro-FMRFamide-related neuropeptide VF [Cleaved into: Neuropeptide NPSF; Neuropeptide RFRP-1; Neuropeptide RFRP-2; Neuropeptide NPVF (Neuropeptide RFRP-3)]
SynonymsC7orf9
RFRP
DescriptionFUNCTION: Neuropeptide RFRP-1 acts as a potent negative regulator of gonadotropin synthesis and secretion. Neuropeptides NPSF and NPVF efficiently inhibit forskolin-induced production of cAMP, but RFRP-2 shows no inhibitory activity. Neuropeptide RFRP-1 induces secretion of prolactin in rats. Neuropeptide NPVF blocks morphine-induced analgesia. .

AccessionsQ9HCQ7
ENST00000222674.2 [Q9HCQ7-1]