Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| mucosal invariant T cell | 11 studies | 23% ± 6% | |
| enterocyte | 6 studies | 28% ± 4% | |
| epithelial cell of proximal tubule | 5 studies | 27% ± 12% | |
| mesothelial cell | 5 studies | 30% ± 13% | |
| CD4-positive, alpha-beta T cell | 5 studies | 18% ± 2% | |
| type II pneumocyte | 5 studies | 17% ± 1% | |
| placental villous trophoblast | 3 studies | 50% ± 17% | |
| enteroendocrine cell | 3 studies | 20% ± 2% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| placenta | 3 studies | 32% ± 10% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| prostate | 94% | 4589.64 | 230 / 245 | 96% | 66.42 | 483 / 502 |
| kidney | 100% | 4601.15 | 89 / 89 | 85% | 48.84 | 765 / 901 |
| liver | 96% | 1155.80 | 218 / 226 | 73% | 16.84 | 296 / 406 |
| intestine | 97% | 1938.55 | 938 / 966 | 50% | 9.11 | 263 / 527 |
| lung | 98% | 1449.42 | 566 / 578 | 46% | 16.79 | 531 / 1155 |
| thymus | 38% | 156.64 | 248 / 653 | 78% | 32.97 | 471 / 605 |
| breast | 98% | 1394.85 | 448 / 459 | 10% | 1.02 | 107 / 1118 |
| spleen | 100% | 1291.61 | 241 / 241 | 0% | 0 | 0 / 0 |
| skin | 94% | 2520.33 | 1695 / 1809 | 5% | 0.69 | 24 / 472 |
| adipose | 99% | 2422.85 | 1187 / 1204 | 0% | 0 | 0 / 0 |
| stomach | 38% | 134.16 | 137 / 359 | 45% | 7.56 | 128 / 286 |
| adrenal gland | 71% | 614.66 | 183 / 258 | 10% | 1.91 | 23 / 230 |
| ovary | 72% | 630.53 | 130 / 180 | 6% | 0.87 | 26 / 430 |
| esophagus | 40% | 171.85 | 579 / 1445 | 37% | 7.19 | 67 / 183 |
| uterus | 60% | 286.16 | 102 / 170 | 13% | 2.35 | 58 / 459 |
| pancreas | 44% | 157.97 | 144 / 328 | 28% | 4.38 | 50 / 178 |
| peripheral blood | 65% | 438.17 | 606 / 929 | 0% | 0 | 0 / 0 |
| heart | 45% | 212.17 | 389 / 861 | 0% | 0 | 0 / 0 |
| bladder | 19% | 67.10 | 4 / 21 | 19% | 3.84 | 94 / 504 |
| muscle | 26% | 127.48 | 211 / 803 | 0% | 0 | 0 / 0 |
| blood vessel | 16% | 81.01 | 220 / 1335 | 0% | 0 | 0 / 0 |
| brain | 5% | 17.18 | 145 / 2642 | 5% | 0.55 | 34 / 705 |
| lymph node | 0% | 0 | 0 / 0 | 7% | 0.60 | 2 / 29 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 45 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0031295 | Biological process | T cell costimulation |
| GO_0016486 | Biological process | peptide hormone processing |
| GO_0061025 | Biological process | membrane fusion |
| GO_0007155 | Biological process | cell adhesion |
| GO_0036343 | Biological process | psychomotor behavior |
| GO_0050919 | Biological process | negative chemotaxis |
| GO_0033632 | Biological process | regulation of cell-cell adhesion mediated by integrin |
| GO_0046813 | Biological process | receptor-mediated virion attachment to host cell |
| GO_0046718 | Biological process | symbiont entry into host cell |
| GO_0043542 | Biological process | endothelial cell migration |
| GO_0001666 | Biological process | response to hypoxia |
| GO_0006508 | Biological process | proteolysis |
| GO_0019065 | Biological process | receptor-mediated endocytosis of virus by host cell |
| GO_0001662 | Biological process | behavioral fear response |
| GO_0008284 | Biological process | positive regulation of cell population proliferation |
| GO_0120116 | Biological process | glucagon processing |
| GO_0035641 | Biological process | locomotory exploration behavior |
| GO_0010716 | Biological process | negative regulation of extracellular matrix disassembly |
| GO_0042110 | Biological process | T cell activation |
| GO_0090024 | Biological process | negative regulation of neutrophil chemotaxis |
| GO_0016324 | Cellular component | apical plasma membrane |
| GO_0005576 | Cellular component | extracellular region |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0045121 | Cellular component | membrane raft |
| GO_0030139 | Cellular component | endocytic vesicle |
| GO_0016020 | Cellular component | membrane |
| GO_0070062 | Cellular component | extracellular exosome |
| GO_0005925 | Cellular component | focal adhesion |
| GO_0009986 | Cellular component | cell surface |
| GO_0031258 | Cellular component | lamellipodium membrane |
| GO_0046581 | Cellular component | intercellular canaliculus |
| GO_0030027 | Cellular component | lamellipodium |
| GO_0005765 | Cellular component | lysosomal membrane |
| GO_0042803 | Molecular function | protein homodimerization activity |
| GO_0008239 | Molecular function | dipeptidyl-peptidase activity |
| GO_0042802 | Molecular function | identical protein binding |
| GO_0005102 | Molecular function | signaling receptor binding |
| GO_0001618 | Molecular function | virus receptor activity |
| GO_0002020 | Molecular function | protease binding |
| GO_0008236 | Molecular function | serine-type peptidase activity |
| GO_0004177 | Molecular function | aminopeptidase activity |
| GO_0045499 | Molecular function | chemorepellent activity |
| GO_0005515 | Molecular function | protein binding |
| GO_0004252 | Molecular function | serine-type endopeptidase activity |
| Gene name | DPP4 |
| Protein name | Dipeptidyl peptidase 4 (EC 3.4.14.5) (ADABP) (Adenosine deaminase complexing protein 2) (ADCP-2) (Dipeptidyl peptidase IV) (DPP IV) (T-cell activation antigen CD26) (TP103) (CD antigen CD26) [Cleaved into: Dipeptidyl peptidase 4 membrane form (Dipeptidyl peptidase IV membrane form); Dipeptidyl peptidase 4 soluble form (Dipeptidyl peptidase IV soluble form)] Dipeptidyl peptidase 4 Dipeptidyl peptidase 4 (EC 3.4.14.5) (Dipeptidyl peptidase IV) (T-cell activation antigen CD26) dipeptidyl-peptidase IV (EC 3.4.14.5) |
| Synonyms | CD26 ADCP2 hCG_39008 |
| Description | FUNCTION: Cell surface glycoprotein receptor involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation . Acts as a positive regulator of T-cell coactivation, by binding at least ADA, CAV1, IGF2R, and PTPRC . Its binding to CAV1 and CARD11 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner . Its interaction with ADA also regulates lymphocyte-epithelial cell adhesion . In association with FAP is involved in the pericellular proteolysis of the extracellular matrix (ECM), the migration and invasion of endothelial cells into the ECM . May be involved in the promotion of lymphatic endothelial cells adhesion, migration and tube formation . When overexpressed, enhanced cell proliferation, a process inhibited by GPC3 . Acts also as a serine exopeptidase with a dipeptidyl peptidase activity that regulates various physiological processes by cleaving peptides in the circulation, including many chemokines, mitogenic growth factors, neuropeptides and peptide hormones such as brain natriuretic peptide 32 . Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline . .; FUNCTION: (Microbial infection) Acts as a receptor for human coronavirus MERS-CoV-2. . |
| Accessions | A0A7I2V501 F8WE17 ENST00000676479.1 ENST00000676810.1 A0A7I2V2X8 ENST00000678566.1 A0A7I2V2I2 ENST00000416189.6 ENST00000679104.1 F8WBB6 ENST00000360534.8 ENST00000494507.2 ENST00000434918.6 ENST00000413651.3 A0A7I2V5R8 ENST00000676768.1 P27487 A0A7I2V3F5 ENST00000678668.1 ENST00000676624.1 A0A7I2V2R5 |
