INHA report

I. Expression across cell types

Insufficient scRNA-seq data for expression of INHA at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of INHA at tissue level.

III. Associated gene sets

GO_0045786Biological processnegative regulation of cell cycle
GO_0042541Biological processhemoglobin biosynthetic process
GO_0001541Biological processovarian follicle development
GO_0007165Biological processsignal transduction
GO_0007267Biological processcell-cell signaling
GO_0042326Biological processnegative regulation of phosphorylation
GO_0046882Biological processnegative regulation of follicle-stimulating hormone secretion
GO_0030218Biological processerythrocyte differentiation
GO_0045650Biological processnegative regulation of macrophage differentiation
GO_0030154Biological processcell differentiation
GO_0008584Biological processmale gonad development
GO_0032689Biological processnegative regulation of type II interferon production
GO_0001501Biological processskeletal system development
GO_0046881Biological processpositive regulation of follicle-stimulating hormone secretion
GO_0045578Biological processnegative regulation of B cell differentiation
GO_0042127Biological processregulation of cell population proliferation
GO_0051726Biological processregulation of cell cycle
GO_0007166Biological processcell surface receptor signaling pathway
GO_0005615Cellular componentextracellular space
GO_0005576Cellular componentextracellular region
GO_0001750Cellular componentphotoreceptor outer segment
GO_0034673Cellular componentinhibin-betaglycan-ActRII complex
GO_0001917Cellular componentphotoreceptor inner segment
GO_0043025Cellular componentneuronal cell body
GO_0043513Cellular componentinhibin B complex
GO_0043512Cellular componentinhibin A complex
GO_0044877Molecular functionprotein-containing complex binding
GO_0005179Molecular functionhormone activity
GO_0005102Molecular functionsignaling receptor binding
GO_0008083Molecular functiongrowth factor activity
GO_0034711Molecular functioninhibin binding
GO_0005515Molecular functionprotein binding
GO_0005125Molecular functioncytokine activity

IV. Literature review

[source]
Gene nameINHA
Protein nameInhibin alpha chain
Synonyms
DescriptionFUNCTION: Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins.

AccessionsB6E5W7
P05111
ENST00000243786.3