I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| hepatocyte | 6 studies | 53% ± 24% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| hepatocyte | 6 studies | 53% ± 24% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| liver | 3 studies | 34% ± 11% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| liver | 100% | 30818.71 | 226 / 226 | 99% | 1027.47 | 401 / 406 |
| brain | 72% | 15.64 | 1894 / 2642 | 63% | 4.33 | 446 / 705 |
| kidney | 91% | 92.74 | 81 / 89 | 37% | 39.75 | 330 / 901 |
| ovary | 95% | 3067.67 | 171 / 180 | 10% | 0.60 | 44 / 430 |
| pancreas | 31% | 6.01 | 101 / 328 | 52% | 10.25 | 93 / 178 |
| uterus | 60% | 117.02 | 102 / 170 | 7% | 0.60 | 34 / 459 |
| breast | 51% | 35.46 | 235 / 459 | 4% | 1.25 | 43 / 1118 |
| adipose | 53% | 90.81 | 634 / 1204 | 0% | 0 | 0 / 0 |
| lung | 37% | 9.77 | 215 / 578 | 11% | 4.15 | 132 / 1155 |
| intestine | 20% | 2.51 | 198 / 966 | 19% | 3.00 | 98 / 527 |
| spleen | 39% | 57.01 | 94 / 241 | 0% | 0 | 0 / 0 |
| stomach | 18% | 1.77 | 66 / 359 | 20% | 2.72 | 56 / 286 |
| adrenal gland | 32% | 5.82 | 83 / 258 | 4% | 0.44 | 10 / 230 |
| heart | 33% | 18.01 | 287 / 861 | 0% | 0 | 0 / 0 |
| esophagus | 15% | 3.85 | 215 / 1445 | 18% | 2.21 | 33 / 183 |
| blood vessel | 28% | 7.18 | 375 / 1335 | 0% | 0 | 0 / 0 |
| thymus | 18% | 2.60 | 117 / 653 | 2% | 0.16 | 15 / 605 |
| bladder | 10% | 0.62 | 2 / 21 | 10% | 0.81 | 50 / 504 |
| skin | 14% | 2.33 | 251 / 1809 | 5% | 0.38 | 22 / 472 |
| muscle | 15% | 3.13 | 124 / 803 | 0% | 0 | 0 / 0 |
| peripheral blood | 14% | 5.69 | 131 / 929 | 0% | 0 | 0 / 0 |
| prostate | 11% | 1.22 | 28 / 245 | 1% | 0.03 | 4 / 502 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 45 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0007165 | Biological process | signal transduction |
| GO_0014070 | Biological process | response to organic cyclic compound |
| GO_0008286 | Biological process | insulin receptor signaling pathway |
| GO_0030307 | Biological process | positive regulation of cell growth |
| GO_0042246 | Biological process | tissue regeneration |
| GO_0090090 | Biological process | negative regulation of canonical Wnt signaling pathway |
| GO_0043567 | Biological process | regulation of insulin-like growth factor receptor signaling pathway |
| GO_0005615 | Cellular component | extracellular space |
| GO_0005788 | Cellular component | endoplasmic reticulum lumen |
| GO_0005576 | Cellular component | extracellular region |
| GO_0005794 | Cellular component | Golgi apparatus |
| GO_0005520 | Molecular function | insulin-like growth factor binding |
| GO_0031995 | Molecular function | insulin-like growth factor II binding |
| GO_0005102 | Molecular function | signaling receptor binding |
| GO_0005515 | Molecular function | protein binding |
| GO_0031994 | Molecular function | insulin-like growth factor I binding |
| Gene name | IGFBP1 |
| Protein name | Insulin-like growth factor-binding protein 1 Insulin-like growth factor-binding protein 1 (IBP-1) (IGF-binding protein 1) (IGFBP-1) (Placental protein 12) (PP12) |
| Synonyms | IBP1 |
| Description | FUNCTION: IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. Promotes cell migration. . FUNCTION: IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. Promotes cell migration. . FUNCTION: IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. Promotes cell migration. . FUNCTION: IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. Promotes cell migration. . FUNCTION: IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. Promotes cell migration. . |
| Accessions | C1K3N3 P08833 C9J6H2 Q6PEY6 C9JXF9 ENST00000468955.1 ENST00000457280.5 ENST00000275525.8 |
