AGRP | OmnibusX

Name	Number of supported studies	Average coverage
alveolar macrophage	4 studies	18% ± 2%	Explore

sc-RNAseq data

Insufficient scRNA-seq data for expression of AGRP at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
adrenal gland	100%	357.88	258 / 258	89%	164.64	205 / 230
lung	99%	84.85	573 / 578	44%	1.61	507 / 1155
brain	93%	67.41	2465 / 2642	24%	0.41	167 / 705
kidney	94%	17.66	84 / 89	18%	0.40	164 / 901
ovary	79%	6.88	143 / 180	26%	0.45	113 / 430
spleen	98%	19.39	237 / 241	0%	0	0 / 0
prostate	73%	4.64	180 / 245	3%	0.06	17 / 502
pancreas	23%	1.14	75 / 328	53%	2.39	94 / 178
peripheral blood	60%	4.21	554 / 929	0%	0	0 / 0
thymus	38%	2.00	250 / 653	16%	0.39	94 / 605
breast	40%	2.54	183 / 459	11%	0.21	126 / 1118
liver	34%	1.85	77 / 226	12%	0.45	50 / 406
intestine	34%	1.70	332 / 966	12%	0.25	62 / 527
skin	33%	1.70	599 / 1809	10%	0.51	49 / 472
stomach	21%	0.94	77 / 359	16%	0.30	47 / 286
esophagus	19%	0.80	275 / 1445	19%	0.45	34 / 183
uterus	27%	1.36	46 / 170	9%	0.19	43 / 459
bladder	24%	1.90	5 / 21	12%	0.41	60 / 504
lymph node	0%	0	0 / 0	34%	0.62	10 / 29
adipose	22%	1.10	269 / 1204	0%	0	0 / 0
blood vessel	19%	1.00	254 / 1335	0%	0	0 / 0
heart	18%	0.78	157 / 861	0%	0	0 / 0
tonsil	0%	0	0 / 0	9%	0.12	4 / 45
muscle	4%	0.17	36 / 803	0%	0	0 / 0
eye	0%	0	0 / 0	4%	0.07	3 / 80
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0007631	Biological process	feeding behavior
GO_0048571	Biological process	long-day photoperiodism
GO_0008343	Biological process	adult feeding behavior
GO_0032868	Biological process	response to insulin
GO_0007218	Biological process	neuropeptide signaling pathway
GO_0060259	Biological process	regulation of feeding behavior
GO_0042755	Biological process	eating behavior
GO_2000253	Biological process	positive regulation of feeding behavior
GO_0007623	Biological process	circadian rhythm
GO_0060135	Biological process	maternal process involved in female pregnancy
GO_0009755	Biological process	hormone-mediated signaling pathway
GO_0005615	Cellular component	extracellular space
GO_0005796	Cellular component	Golgi lumen
GO_0043025	Cellular component	neuronal cell body
GO_0005102	Molecular function	signaling receptor binding
GO_0005184	Molecular function	neuropeptide hormone activity
GO_0070996	Molecular function	type 1 melanocortin receptor binding

Gene name	AGRP
Protein name	Agouti-related protein Agouti related protein homolog (Mouse) (Agouti-related protein)
Synonyms	ART hCG_28814 AGRT AgRP
Description	FUNCTION: Plays a role in weight homeostasis. Involved in the control of feeding behavior through the central melanocortin system. Acts as alpha melanocyte-stimulating hormone antagonist by inhibiting cAMP production mediated by stimulation of melanocortin receptors within the hypothalamus and adrenal gland. Has very low activity with MC5R (By similarity). Is an inverse agonist for MC3R and MC4R being able to suppress their constitutive activity. It promotes MC3R and MC4R endocytosis in an arrestin-dependent manner. .
Accessions	O00253 ENST00000290953.3 C6SUN5

AGRP report