LPA | OmnibusX

Name	Number of supported studies	Average coverage
hepatocyte	3 studies	41% ± 13%	Explore

sc-RNAseq data

Insufficient scRNA-seq data for expression of LPA at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
liver	100%	3755.85	226 / 226	84%	9.29	340 / 406
pancreas	98%	33.82	322 / 328	1%	0.01	1 / 178
prostate	95%	60.46	232 / 245	4%	0.06	19 / 502
kidney	83%	35.89	74 / 89	2%	0.03	16 / 901
ovary	80%	17.30	144 / 180	0%	0.00	1 / 430
bladder	67%	45.71	14 / 21	6%	0.13	30 / 504
adrenal gland	62%	13.00	161 / 258	5%	0.14	12 / 230
uterus	57%	9.84	97 / 170	6%	0.09	27 / 459
brain	56%	16.70	1491 / 2642	0%	0.00	1 / 705
thymus	48%	9.94	316 / 653	2%	0.04	13 / 605
lung	37%	5.74	213 / 578	2%	0.03	21 / 1155
esophagus	31%	5.79	450 / 1445	3%	0.04	6 / 183
intestine	32%	3.39	309 / 966	1%	0.04	3 / 527
skin	11%	1.05	190 / 1809	0%	0	0 / 472
adipose	9%	1.04	106 / 1204	0%	0	0 / 0
breast	8%	0.82	38 / 459	0%	0.00	2 / 1118
blood vessel	6%	0.45	75 / 1335	0%	0	0 / 0
stomach	5%	0.37	18 / 359	0%	0.00	1 / 286
muscle	3%	0.18	23 / 803	0%	0	0 / 0
heart	3%	0.41	22 / 861	0%	0	0 / 0
spleen	2%	5.39	6 / 241	0%	0	0 / 0
peripheral blood	2%	0.16	16 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
eye	0%	0	0 / 0	0%	0	0 / 80
gingiva	0%	0	0 / 0	0%	0	0 / 0
lymph node	0%	0	0 / 0	0%	0	0 / 29
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
tonsil	0%	0	0 / 0	0%	0	0 / 45
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0008015	Biological process	blood circulation
GO_0006629	Biological process	lipid metabolic process
GO_0006508	Biological process	proteolysis
GO_0006869	Biological process	lipid transport
GO_0005615	Cellular component	extracellular space
GO_0034358	Cellular component	plasma lipoprotein particle
GO_0005576	Cellular component	extracellular region
GO_0008201	Molecular function	heparin binding
GO_0004175	Molecular function	endopeptidase activity
GO_0004252	Molecular function	serine-type endopeptidase activity
GO_0004866	Molecular function	endopeptidase inhibitor activity
GO_0005102	Molecular function	signaling receptor binding
GO_0001968	Molecular function	fibronectin binding
GO_0005515	Molecular function	protein binding
GO_0034185	Molecular function	apolipoprotein binding

Gene name	LPA
Protein name	Lipoprotein, Lp(A) Apolipoprotein(a) (Apo(a)) (Lp(a)) (EC 3.4.21.-)
Synonyms
Description	FUNCTION: Apo(a) is the main constituent of lipoprotein(a) (Lp(a)). It has serine proteinase activity and is able of autoproteolysis. Inhibits tissue-type plasminogen activator 1. Lp(a) may be a ligand for megalin/Gp 330. .
Accessions	ENST00000316300.10 P08519 Q1HP67

LPA report