Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| endothelial cell | 10 studies | 27% ± 10% | |
| oligodendrocyte precursor cell | 9 studies | 27% ± 12% | |
| astrocyte | 7 studies | 29% ± 11% | |
| interneuron | 6 studies | 34% ± 22% | |
| microglial cell | 6 studies | 23% ± 6% | |
| epithelial cell | 6 studies | 34% ± 14% | |
| type II pneumocyte | 6 studies | 19% ± 5% | |
| GABAergic neuron | 6 studies | 39% ± 19% | |
| oligodendrocyte | 6 studies | 24% ± 7% | |
| macrophage | 6 studies | 25% ± 7% | |
| neuron | 5 studies | 26% ± 9% | |
| glutamatergic neuron | 5 studies | 50% ± 21% | |
| type I pneumocyte | 4 studies | 20% ± 5% | |
| endothelial cell of lymphatic vessel | 4 studies | 19% ± 4% | |
| classical monocyte | 3 studies | 17% ± 1% | |
| granule cell | 3 studies | 18% ± 3% | |
| myeloid cell | 3 studies | 19% ± 1% | |
| dendritic cell | 3 studies | 21% ± 4% | |
| ciliated cell | 3 studies | 24% ± 3% | |
| pericyte | 3 studies | 24% ± 3% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| brain | 8 studies | 35% ± 17% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| esophagus | 100% | 3305.90 | 1445 / 1445 | 100% | 43.38 | 183 / 183 |
| lung | 100% | 3551.92 | 578 / 578 | 100% | 32.90 | 1155 / 1155 |
| breast | 100% | 3076.41 | 459 / 459 | 100% | 37.19 | 1116 / 1118 |
| prostate | 100% | 3200.97 | 245 / 245 | 100% | 28.46 | 500 / 502 |
| ovary | 100% | 2199.83 | 180 / 180 | 100% | 21.52 | 428 / 430 |
| uterus | 100% | 2679.12 | 170 / 170 | 99% | 27.25 | 456 / 459 |
| brain | 99% | 1754.32 | 2617 / 2642 | 100% | 22.04 | 705 / 705 |
| pancreas | 100% | 1686.21 | 328 / 328 | 99% | 21.96 | 176 / 178 |
| thymus | 100% | 2748.34 | 653 / 653 | 99% | 21.95 | 598 / 605 |
| bladder | 100% | 3235.52 | 21 / 21 | 99% | 26.26 | 498 / 504 |
| intestine | 100% | 3397.97 | 966 / 966 | 98% | 27.73 | 519 / 527 |
| kidney | 100% | 2612.44 | 89 / 89 | 98% | 20.97 | 883 / 901 |
| stomach | 100% | 2661.08 | 359 / 359 | 98% | 29.14 | 280 / 286 |
| adrenal gland | 100% | 2987.75 | 258 / 258 | 97% | 17.18 | 222 / 230 |
| skin | 100% | 3110.32 | 1809 / 1809 | 94% | 24.58 | 444 / 472 |
| liver | 100% | 2367.10 | 226 / 226 | 92% | 13.83 | 372 / 406 |
| blood vessel | 100% | 3125.37 | 1335 / 1335 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 17.71 | 29 / 29 |
| muscle | 100% | 2235.84 | 803 / 803 | 0% | 0 | 0 / 0 |
| spleen | 100% | 2622.47 | 241 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 29.74 | 45 / 45 |
| ureter | 0% | 0 | 0 / 0 | 100% | 19.80 | 1 / 1 |
| adipose | 100% | 2947.00 | 1203 / 1204 | 0% | 0 | 0 / 0 |
| heart | 98% | 1814.14 | 846 / 861 | 0% | 0 | 0 / 0 |
| peripheral blood | 94% | 2128.52 | 877 / 929 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 66% | 8.00 | 53 / 80 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0007420 | Biological process | brain development |
| GO_0072583 | Biological process | clathrin-dependent endocytosis |
| GO_0031623 | Biological process | receptor internalization |
| GO_0008333 | Biological process | endosome to lysosome transport |
| GO_0090090 | Biological process | negative regulation of canonical Wnt signaling pathway |
| GO_0021860 | Biological process | pyramidal neuron development |
| GO_0010008 | Cellular component | endosome membrane |
| GO_0030136 | Cellular component | clathrin-coated vesicle |
| GO_0005794 | Cellular component | Golgi apparatus |
| GO_0005102 | Molecular function | signaling receptor binding |
| GO_0005515 | Molecular function | protein binding |
| GO_0005524 | Molecular function | ATP binding |
| GO_0004672 | Molecular function | protein kinase activity |
| Gene name | SCYL2 |
| Protein name | SCY1-like protein 2 (Coated vesicle-associated kinase of 104 kDa) SCY1 like pseudokinase 2 |
| Synonyms | CVAK104 KIAA1360 |
| Description | FUNCTION: Component of the AP2-containing clathrin coat that may regulate clathrin-dependent trafficking at plasma membrane, TGN and endosomal system (Probable). A possible serine/threonine-protein kinase toward the beta2-subunit of the plasma membrane adapter complex AP2 and other proteins in presence of poly-L-lysine has not been confirmed . By regulating the expression of excitatory receptors at synapses, plays an essential role in neuronal function and signaling and in brain development (By similarity). . |
| Accessions | H0YIK6 F8VSC5 ENST00000550251.2 F8VPW3 Q6P3W7 ENST00000635101.1 A0A0U1RQQ9 H0YI32 ENST00000548871.1 ENST00000360820.7 ENST00000548392.5 ENST00000549687.5 |