TESPA1 | OmnibusX

Name	Number of supported studies	Average coverage
mast cell	20 studies	31% ± 17%	Explore
CD4-positive, alpha-beta T cell	17 studies	27% ± 10%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	14 studies	24% ± 6%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	9 studies	23% ± 5%	Explore
CD4-positive, alpha-beta memory T cell	8 studies	21% ± 6%	Explore
T cell	8 studies	22% ± 5%	Explore
regulatory T cell	6 studies	21% ± 6%	Explore
hematopoietic stem cell	5 studies	27% ± 8%	Explore
T follicular helper cell	5 studies	23% ± 4%	Explore
glutamatergic neuron	5 studies	49% ± 14%	Explore
megakaryocyte-erythroid progenitor cell	4 studies	51% ± 15%	Explore
hematopoietic precursor cell	3 studies	28% ± 3%	Explore
effector memory CD4-positive, alpha-beta T cell	3 studies	28% ± 3%	Explore
CD8-positive, alpha-beta T cell	3 studies	27% ± 8%	Explore

Name	Number of supported studies	Average coverage
brain	4 studies	34% ± 8%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
lung	97%	358.92	562 / 578	72%	2.21	828 / 1155
prostate	72%	166.82	177 / 245	47%	1.01	234 / 502
uterus	72%	149.11	122 / 170	44%	1.03	202 / 459
bladder	71%	174.48	15 / 21	39%	1.00	195 / 504
ovary	91%	378.47	164 / 180	18%	0.31	79 / 430
stomach	51%	89.01	184 / 359	49%	1.31	141 / 286
lymph node	0%	0	0 / 0	100%	24.38	29 / 29
spleen	100%	900.14	241 / 241	0%	0	0 / 0
breast	33%	49.36	152 / 459	66%	2.42	737 / 1118
peripheral blood	99%	1596.58	919 / 929	0%	0	0 / 0
intestine	61%	319.43	593 / 966	37%	0.99	194 / 527
kidney	24%	68.97	21 / 89	71%	2.92	644 / 901
esophagus	55%	119.93	797 / 1445	40%	0.92	73 / 183
brain	49%	3302.84	1296 / 2642	43%	7.60	302 / 705
thymus	41%	112.13	266 / 653	50%	8.86	300 / 605
skin	30%	52.27	548 / 1809	51%	2.75	241 / 472
tonsil	0%	0	0 / 0	80%	3.34	36 / 45
pancreas	2%	1.80	5 / 328	65%	2.39	115 / 178
adipose	60%	117.85	728 / 1204	0%	0	0 / 0
liver	5%	5.86	11 / 226	19%	0.58	77 / 406
blood vessel	13%	28.69	175 / 1335	0%	0	0 / 0
adrenal gland	0%	0.43	1 / 258	9%	0.20	20 / 230
eye	0%	0	0 / 0	9%	0.24	7 / 80
heart	9%	13.80	75 / 861	0%	0	0 / 0
muscle	1%	1.49	9 / 803	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0033077	Biological process	T cell differentiation in thymus
GO_0033089	Biological process	positive regulation of T cell differentiation in thymus
GO_0050862	Biological process	positive regulation of T cell receptor signaling pathway
GO_0008104	Biological process	protein localization
GO_0036399	Biological process	TCR signalosome assembly
GO_0010387	Biological process	COP9 signalosome assembly
GO_0005737	Cellular component	cytoplasm
GO_0005829	Cellular component	cytosol
GO_0036398	Cellular component	TCR signalosome
GO_0008180	Cellular component	COP9 signalosome
GO_0005789	Cellular component	endoplasmic reticulum membrane
GO_0043274	Molecular function	phospholipase binding
GO_0005102	Molecular function	signaling receptor binding

Gene name	TESPA1
Protein name	Thymocyte expressed, positive selection associated 1 Protein TESPA1 (Thymocyte-expressed positive selection-associated protein 1)
Synonyms	HSPC257 KIAA0748
Description	FUNCTION: Required for the development and maturation of T-cells, its function being essential for the late stages of thymocyte development (By similarity). Plays a role in T-cell antigen receptor (TCR)-mediated activation of the ERK and NFAT signaling pathways, possibly by serving as a scaffolding protein that promotes the assembly of the LAT signalosome in thymocytes. May play a role in the regulation of inositol 1,4,5-trisphosphate receptor-mediated Ca(2+) release and mitochondrial Ca(2+) uptake via the mitochondria-associated endoplasmic reticulum membrane (MAM) compartment. .
Accessions	ENST00000525978.5 E9PHY9 ENST00000533446.5 ENST00000526532.5 ENST00000524668.5 ENST00000532804.5 [A2RU30-2] E9PPW8 A2RU30 E9PIN8 ENST00000449076.6 [A2RU30-1] H0YEX3 ENST00000316577.12 [A2RU30-1] E9PM24 ENST00000528240.1 E9PIT9 H0YDP3 ENST00000531122.5 [A2RU30-2] ENST00000533607.1 ENST00000532757.5 E9PN46 ENST00000524923.5 ENST00000524622.5 [A2RU30-2]

TESPA1 report