I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| astrocyte | 12 studies | 38% ± 17% | |
| ependymal cell | 3 studies | 41% ± 13% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| astrocyte | 12 studies | 38% ± 17% | |
| ependymal cell | 3 studies | 41% ± 13% |
Insufficient scRNA-seq data for expression of LAMA1 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| kidney | 100% | 1555.48 | 89 / 89 | 75% | 6.74 | 674 / 901 |
| thymus | 100% | 1428.03 | 652 / 653 | 69% | 5.39 | 420 / 605 |
| skin | 74% | 1337.08 | 1332 / 1809 | 72% | 15.14 | 340 / 472 |
| brain | 80% | 456.86 | 2114 / 2642 | 56% | 3.14 | 397 / 705 |
| ovary | 96% | 1026.14 | 172 / 180 | 32% | 2.72 | 139 / 430 |
| uterus | 82% | 372.91 | 139 / 170 | 26% | 3.24 | 120 / 459 |
| lung | 79% | 256.19 | 458 / 578 | 28% | 3.90 | 327 / 1155 |
| breast | 82% | 579.76 | 377 / 459 | 19% | 0.90 | 214 / 1118 |
| pancreas | 71% | 385.02 | 234 / 328 | 9% | 0.44 | 16 / 178 |
| adipose | 72% | 357.94 | 865 / 1204 | 0% | 0 | 0 / 0 |
| bladder | 57% | 176.05 | 12 / 21 | 14% | 1.23 | 70 / 504 |
| prostate | 60% | 160.39 | 146 / 245 | 3% | 0.25 | 15 / 502 |
| intestine | 47% | 160.94 | 458 / 966 | 7% | 0.50 | 37 / 527 |
| esophagus | 16% | 38.67 | 232 / 1445 | 27% | 3.38 | 50 / 183 |
| spleen | 39% | 101.69 | 95 / 241 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 21% | 0.96 | 17 / 80 |
| blood vessel | 18% | 51.54 | 243 / 1335 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 18% | 1.41 | 8 / 45 |
| heart | 15% | 43.29 | 127 / 861 | 0% | 0 | 0 / 0 |
| stomach | 5% | 9.36 | 17 / 359 | 5% | 1.46 | 14 / 286 |
| liver | 3% | 5.70 | 6 / 226 | 5% | 1.43 | 21 / 406 |
| muscle | 3% | 7.29 | 28 / 803 | 0% | 0 | 0 / 0 |
| adrenal gland | 1% | 2.23 | 2 / 258 | 2% | 0.18 | 5 / 230 |
| peripheral blood | 0% | 6.14 | 4 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0045198 | Biological process | establishment of epithelial cell apical/basal polarity |
| GO_0045995 | Biological process | regulation of embryonic development |
| GO_0002011 | Biological process | morphogenesis of an epithelial sheet |
| GO_0060445 | Biological process | branching involved in salivary gland morphogenesis |
| GO_0061304 | Biological process | retinal blood vessel morphogenesis |
| GO_0031175 | Biological process | neuron projection development |
| GO_0060441 | Biological process | epithelial tube branching involved in lung morphogenesis |
| GO_0051149 | Biological process | positive regulation of muscle cell differentiation |
| GO_2001046 | Biological process | positive regulation of integrin-mediated signaling pathway |
| GO_0007155 | Biological process | cell adhesion |
| GO_0045785 | Biological process | positive regulation of cell adhesion |
| GO_0030334 | Biological process | regulation of cell migration |
| GO_0110011 | Biological process | regulation of basement membrane organization |
| GO_0007166 | Biological process | cell surface receptor signaling pathway |
| GO_0005615 | Cellular component | extracellular space |
| GO_0005576 | Cellular component | extracellular region |
| GO_0016020 | Cellular component | membrane |
| GO_0062023 | Cellular component | collagen-containing extracellular matrix |
| GO_0031012 | Cellular component | extracellular matrix |
| GO_0005606 | Cellular component | laminin-1 complex |
| GO_0005911 | Cellular component | cell-cell junction |
| GO_0098637 | Cellular component | protein complex involved in cell-matrix adhesion |
| GO_0005604 | Cellular component | basement membrane |
| GO_0005608 | Cellular component | laminin-3 complex |
| GO_0005201 | Molecular function | extracellular matrix structural constituent |
| GO_0005102 | Molecular function | signaling receptor binding |
| GO_0043208 | Molecular function | glycosphingolipid binding |
| GO_0005515 | Molecular function | protein binding |
| Gene name | LAMA1 |
| Protein name | Laminin subunit alpha-1 (Laminin A chain) (Laminin-1 subunit alpha) (Laminin-3 subunit alpha) (S-laminin subunit alpha) (S-LAM alpha) Alternative protein LAMA1 LAMA1 protein |
| Synonyms | LAMA |
| Description | FUNCTION: Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. |
| Accessions | ENST00000389658.4 L8ECC5 L8E9C2 Q7Z5W6 P25391 Q6P6D3 |
